A Switched-Mode Breast Coil for 7 T MRI Using Forced-Current Excitation.

In high-field magnetic resonance imaging, the radio frequency wavelength within the human body is comparable to anatomical dimensions, resulting in B1 inhomogeneity and nonuniform sensitivity patterns. Thus, this relatively short wavelength presents engineering challenges for RF coil design. In this study, a bilateral breast coil for (1)H imaging at 7 T was designed and constructed using forced-current excitation. By forcing equal current through the coil elements, we reduce the effects of coupling between the elements to simplify tuning and to ensure a uniform field across both breasts. To combine the benefits of the higher power efficiency of a unilateral coil with the bilateral coverage of a bilateral coil, a switching circuit was implemented to allow the coil to be reconfigured for imaging the left, right, or both breasts.

A 16-channel receive, forced current excitation dual-transmit coil for breast imaging at 7T.

PURPOSE: To enable high spatial and temporal breast imaging resolution via combined use of high field MRI, array coils, and forced current excitation (FCE) multi channel transmit. MATERIALS AND METHODS: A unilateral 16-channel receive array insert was designed for use in a transmit volume coil optimized for quadrature operation with dual-transmit RF shimming at 7 T. Signal-to-noise ratio (SNR) maps, g-factor maps, and high spatial and temporal resolution in vivo images were acquired to demonstrate the utility of the coil architecture. RESULTS: The dual-transmit FCE coil provided homogeneous excitation and the array provided an increase in average SNR of 3.3 times (max 10.8, min 1.5) compared to the volume coil in transmit/receive mode. High resolution accelerated in vivo breast imaging demonstrated the ability to achieve isotropic spatial resolution of 0.5 mm within clinically relevant 90 s scan times, as well as the ability to perform 1.0 mm isotropic resolution imaging, 7 s per dynamics, with the use of bidirectional SENSE acceleration of up to R = 9. CONCLUSION: The FCE design of the transmit coil easily accommodates the addition of a sixteen channel array coil. The improved spatial and temporal resolution provided by the high-field array coil with FCE dual-channel transmit will ultimately be beneficial in lesion detection and characterization.

An eight-channel T/R head coil for parallel transmit MRI at 3T using ultra-low output impedance amplifiers.

Parallel transmit is an emerging technology to address the technical challenges associated with MR imaging at high field strengths. When developing arrays for parallel transmit systems, one of the primary factors to be considered is the mechanism to manage coupling and create independently operating channels. Recent work has demonstrated the use of amplifiers to provide some or all of the channel-to-channel isolation, reducing the need for on-coil decoupling networks in a manner analogous to the use of isolation preamplifiers with receive coils. This paper discusses an eight-channel transmit/receive head array for use with an ultra-low output impedance (ULOI) parallel transmit system. The ULOI amplifiers eliminated the need for a complex lumped element network to decouple the eight-rung array. The design and construction details of the array are discussed in addition to the measurement considerations required for appropriately characterizing an array when using ULOI amplifiers. B1 maps and coupling matrices are used to verify the performance of the system.

Quadrature transmit coil for breast imaging at 7 tesla using forced current excitation for improved homogeneity.

PURPOSE: To demonstrate the use of forced current excitation (FCE) to create homogeneous excitation of the breast at 7 tesla, insensitive to the effects of asymmetries in the electrical environment. MATERIALS AND METHODS: FCE was implemented on two breast coils: one for quadrature (1) H imaging and one for proton-decoupled (13) C spectroscopy. Both were a Helmholtz-saddle combination, with the saddle tuned to 298 MHz for imaging and 75 MHz for spectroscopy. Bench measurements were acquired to demonstrate the ability to force equal currents on elements in the presence of asymmetric loading to improve homogeneity. Modeling and temperature measurements were conducted per safety protocol. B1 mapping, imaging, and proton-decoupled (13) C spectroscopy were demonstrated in vivo. RESULTS: Using FCE to ensure balanced currents on elements enabled straightforward tuning and maintaining of isolation between quadrature elements of the coil. Modeling and bench measurements confirmed homogeneity of the field, which resulted in images with excellent fat suppression and in broadband proton-decoupled carbon-13 spectra. CONCLUSION: FCE is a straightforward approach to ensure equal currents on multiple coil elements and a homogeneous excitation field, insensitive to the effects of asymmetries in the electrical environment. This enabled effective breast imaging and proton-decoupled carbon-13 spectroscopy at 7T.

An insertable nonlinear gradient coil for phase compensation in SEA imaging.

In magnetic resonance imaging with array coils with many elements, as the radiofrequency (RF) coil dimensions approach the voxel dimensions, the phase gradient due to the magnetic field pattern of the coil causes signal cancellation within each voxel. In single echo acquisition (SEA) imaging with coil arrays, a gradient pulse can be applied to compensate for this effect. However, because RF coil phase varies with distance from the array and reverses on opposite sides of a dual-sided array, this method of phase compensation can be optimized for only a single slice at a time. In this study, a nonlinear gradient coil was implemented to provide spatially varying phase compensation to offset the coil phase with slice position for dual-sided arrays of narrow coils. This nonlinear gradient coil allows the use of one phase compensation pulse for imaging multiple slices through a slab, and, importantly, is shown to enable simultaneous SEA imaging from opposite sides of a sample using a dual-sided receive array.

A parallel imaging approach to wide-field MR microscopy.

Magnetic resonance microscopy, suggested in the earliest papers on MRI, has always been limited by the low signal-to-noise ratio resulting from the small voxel size. Magnetic resonance microscopy has largely been enabled by the use of microcoils that provide the signal-to-noise ratio improvement required to overcome this limitation. Concomitant with the small coils is a small field-of-view, which limits the use of magnetic resonance microscopy as a histological tool or for imaging large regions in general. This article describes initial results in wide field-of-view magnetic resonance microscopy using a large array of narrow, parallel coils, which provides a signal-to-noise ratio enhancement as well as the ability to use parallel imaging techniques. Comparison images made between a volume coil and the proposed technique demonstrate reductions in imaging time of more than 100 with no loss in signal-to-noise ratio or resolution.

An Improved Element Design for 64-Channel Planar Imaging.

Investigation of highly accelerated MRI has developed into a lively corner in the hardware and methodology arena in recent years. At the extreme of (one-dimensional) acceleration, our group introduced Single Echo Acquisition (SEA) imaging, in which the need to phase encode a 64×N(readout) image is eliminated and replaced with the well-localized spatial information obtained from an array of 64 very narrow, long, parallel coils. The narrow coil width (2mm) that facilitates this is accompanied by a concomitant constraint on the useful imaging depth. This note describes a 64-element planar array, constructed within the same 8×13cm total footprint as the original SEA array, still enabling full acceleration in one dimension, but with an element design modified to increase the imaging depth. This was accomplished by lowering the outer conducting legs of the planar pair with respect to the center conductor and adding a geometric decoupling configuration away from the imaging field of view. The element has been called a dual-plane pair in that the current carrying rungs in the imaging FOV function exactly as the planar pair, but are simply placed in two separate planes (sides of PCB in this case).

A desktop imaging system for teaching MR engineering.

This paper reports our results in developing a simple MRI system for teaching the basics of MR Engineering at the undergraduate or graduate level. LabVIEW data acquisition cards were used for generating and digitizing the RF signals and controlling gradients and transmit/receive and blanking switches. A very inexpensive and simple magnet reported previously by Sahakian was used to enable simple, projection reconstruction imaging. Students constructed the gradients, RF coils and did system level assembly and programming of the data acquisition system. At the end of the course students were tasked with identifying unknown imaging "phantoms" in their magnet, and then improving the image based on their knowledge.

Highly parallel transmit/receive systems for dynamic MRI.

Dynamic MRI continues to grow in interest and capability with the introduction of 64 and 128 channel receivers, and, more recently, 8 and 16 channel parallel transmitters. This talk will describe progress in developing a 64 channel transmitter and applications in high-speed MR imaging, reaching 1000 frames per second.

Single echo acquisition MRI using RF encoding.

Encoding of spatial information in magnetic resonance imaging is conventionally accomplished by using magnetic field gradients. During gradient encoding, the position in k-space is determined by a time-integral of the gradient field, resulting in a limitation in imaging speed due to either gradient power or secondary effects such as peripheral nerve stimulation. Partial encoding of spatial information through the sensitivity patterns of an array of coils, known as parallel imaging, is widely used to accelerate the imaging, and is complementary to gradient encoding. This paper describes the one-dimensional limit of parallel imaging in which all spatial localization in one dimension is performed through encoding by the radiofrequency (RF) coil. Using a one-dimensional array of long and narrow parallel elements to localize the image information in one direction, an entire image is obtained from a single line of k-space, avoiding rapid or repeated manipulation of gradients. The technique, called single echo acquisition (SEA) imaging, is described, along with the need for a phase compensation gradient pulse to counteract the phase variation contained in the RF coil pattern which would otherwise cause signal cancellation in each imaging voxel. Image reconstruction and resolution enhancement methods compatible with the speed of the technique are discussed. MR movies at frame rates of 125 frames per second are demonstrated, illustrating the ability to monitor the evolution of transverse magnetization to steady state during an MR experiment as well as demonstrating the ability to image rapid motion. Because this technique, like all RF encoding approaches, relies on the inherent spatially varying pattern of the coil and is not a time-integral, it should enable new applications for MRI that were previously inaccessible due to speed constraints, and should be of interest as an approach to extending the limits of detection in MR imaging.

Investigation of coil phase compensation in 3D imaging at very high acceleration factors.

PURPOSE: To investigate the confounding effect of the coil phase in highly accelerated parallel imaging with small coils, contextualize the effect in terms of single-echo acquisition (SEA) imaging, and show that it can be managed in the case of 3D imaging. MATERIALS AND METHODS: The effects of the coil phase variations in a 64-channel array of surface microcoils were modeled. Fully encoded 64 x 128 x 64 (N(phase enc) x N(readout) x N(slice enc)) 3D data sets were obtained, from which factor of 64 accelerated 3D image sets (1 x 128 x 64 each) were extracted from single phase-encoding lines, each representing a different phase compensation value. RESULTS: A comparison of the SEA images indicates that the choice of a compromise value for phase compensation successfully enabled a straightforward extension of SEA imaging to three dimensions. The use of the single compromise compensation value in the 3D acquisition resulted in a signal-to-noise ratio (SNR) penalty ranging from 6% to 41% through the slab when compared to the highest SNR possible using any phase compensation value. CONCLUSION: The coil-related phase shift issues inherent to highly accelerated imaging will require further study, but this work indicates the general nature of the problem and, more auspiciously, shows that it can be mitigated for at least this application.

Progress in visualizing turbulent flow using single-echo acquisition imaging.

MRI of flow remains a challenging problem despite significant improvements in imaging speeds. For periodic flow the acquisition can be gated, synchronizing data acquisition with the flow. However, this method fails to work if the flow is sufficiently fast that turbulence occurs, or when it is sufficiently fast that blurring occurs during the excitation of the spins or the acquisition of the signal. This paper describes recent progress in employing a very fast MR imaging technique, Single Echo Acquisition Imaging (SEA-MRI) and spin-tagging to visualize very rapid and turbulent flow patterns. Demonstrations are done on a separating channel phantom with input flow rates ranging from zero to over 100 cm/sec. Spin-tagging enables a "texture" to be placed on the spins, enabling clear visualization of the complex flow patterns, and in some cases measurement of the flow velocity.

64-channel array coil for single echo acquisition magnetic resonance imaging.

A 64-channel array coil for magnetic resonance imaging (MRI) has been designed and constructed. The coil was built to enable the testing of a new imaging method, single echo acquisition (SEA) MRI, in which an independent full image is acquired with every echo. This is accomplished by entirely eliminating phase encoding and instead using the spatial information obtained from an array of very narrow, long, parallel coils. The planar pair element design proved to be key in achieving well-localized field sensitivity patterns and isolated elements, the crucial requirements for performing SEA. The matching and tuning of the array elements were accomplished on the coil array printed circuit board using varactor diodes biased over the RF lines. The array was successfully used to obtain SEA images as well as conventional partially parallel images at unprecedented acceleration factors.