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Evaluation of the NucliSENS EasyQ KPC assay for detection of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae.

McEwan, A S; Derome, A; Meunier, D; Burns, P J; Woodford, N; Dodgson, A R.

J Clin Microbiol ; 51(6): 1948-50, 2013 Jun.

Article in English | MEDLINE | ID: mdl-23554195

ABSTRACT

The NucliSENS EasyQ KPC assay (bioMérieux SA, Marcy l'Etoile, France) was compared with a routinely used phenotypic method for detection of Enterobacteriaceae producing Klebsiella pneumoniae carbapenemase (KPC)-type carbapenemases, using 806 stool samples and rectal swabs. Compared with the phenotypic method, the EasyQ KPC assay had a sensitivity and specificity of 93.3% and 99.0%, respectively, in this setting, with diverse KPC producers not limited to ST258 Klebsiella pneumoniae.

Subject(s)

Bacterial Proteins/analysis , Bacterial Proteins/genetics , Enterobacteriaceae Infections/microbiology , Enterobacteriaceae/enzymology , Enterobacteriaceae/isolation & purification , beta-Lactamases/analysis , beta-Lactamases/genetics , Feces/microbiology , France , Humans , Rectum/microbiology , Sensitivity and Specificity

ABSTRACT

Subject(s)

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