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1.
Ear Nose Throat J ; 79(6): 456-9, 2000 Jun.
Article in English | MEDLINE | ID: mdl-10893837

ABSTRACT

We report the case of a 62-year-old woman who experienced pneumolabyrinth associated with a perilymphatic fistula. Her condition was diagnosed with the help of computed tomography, which detected the presence of an air bubble in the labyrinth, and middle ear exploration, which revealed that clear fluid was emanating from the round window niche in a manner consistent with the presence of a perilymphatic fistula. The niche was repaired with tragal perichondrium and bolstered with Gelfoam.


Subject(s)
Barotrauma/complications , Fistula/complications , Labyrinth Diseases/etiology , Cochlear Aqueduct , Ear, Inner/diagnostic imaging , Female , Fistula/surgery , Humans , Labyrinth Diseases/surgery , Middle Aged , Tomography, X-Ray Computed
2.
Am J Otol ; 20(6): 712-6, 1999 Nov.
Article in English | MEDLINE | ID: mdl-10565713

ABSTRACT

HYPOTHESIS: Gelfilm offers protection against fibrosis in the middle ear when used in combination with Gelfoam. BACKGROUND: Gelfoam is used routinely as a support structure in the middle ear cleft when ossicular reconstruction and tympanic membrane grafts are performed. It has been recognized that fibrosis may occur in this setting if the middle ear mucosa is denuded. Materials have been used to protect the mucosa in an attempt to prevent scar bands, adhesions, and fibrosis and its potential detriment on hearing. These materials have included Teflon, Silastic, and Gelfilm. Concerns have arisen regarding this mode of therapy and its benefit. METHODS: This study looks at the effects of implanting Gelfoam independently and Gelfoam and Gelfilm concurrently in the bulla cavity of the Mongolian Gerbil. The temporal bones were harvested and evaluated histologically using hemotoxylin and eosin staining for fibrosis. RESULTS: Results demonstrated a decrease in the amount of fibrosis in the animals in which Gelfilm was used to protect the denuded mucosa. No evidence of fibroblast ingrowth or scar bands penetrating the Gelfilm was identified. CONCLUSION: These results suggest that Gelfoam can be used safely in the middle ear cleft to support ossicular prosthesis and tympanic membrane grafts when Gelfilm is used to protect denuded mucosa.


Subject(s)
Disease Models, Animal , Ear, Middle/pathology , Gelatin Sponge, Absorbable/pharmacology , Hemostatics/pharmacology , Animals , Fibrosis/pathology , Fibrosis/prevention & control , Gerbillinae , Male
3.
Head Neck ; 19(8): 659-65, 1997 Dec.
Article in English | MEDLINE | ID: mdl-9406744

ABSTRACT

BACKGROUND: Osseointegrated implants allow patients with oromandibular defects to obtain complete or partial dentition via implant-assisted or implant-borne prostheses. Implants restore masticatory and occlusal function, improving oral intake and articulation. However, use of implants in head and neck cancer patients has been discouraged due to lack of data supporting their utility in these patients. This study attempts to establish the validity of using osseointegrated implants for dental restoration in head and neck cancer patients. METHODS: Six patients who underwent resection/reconstruction for head and neck cancer received osseointegrated implants. Integration was assessed clinically, radiographically, and mechanically at 4-8 months; oral intake, mastication, and articulation were evaluated 6-12 months after receiving the dental prosthesis. RESULTS: Osseointegration occurred in 92% (24/26) of the implants: 100% (14/14) in neomandibles and 83% (10/12) in native mandibles. One patient had implants (2/5) that failed to integrate. The remaining patients' implants were immobile, free of infection, with no osteoradionecrosis. These patients tolerated a regular diet and experienced weight gain and improved articulation. CONCLUSIONS: The advent of osseointegrated implants and their compatibility with native and neomandible allows the restoration of functional dentition in patients undergoing ablative surgery for head and neck cancer.


Subject(s)
Carcinoma, Squamous Cell/surgery , Dental Implantation, Endosseous , Mandibular Neoplasms/surgery , Mouth Neoplasms/surgery , Carcinoma, Squamous Cell/physiopathology , Carcinoma, Squamous Cell/radiotherapy , Combined Modality Therapy , Humans , Mandibular Neoplasms/physiopathology , Mandibular Neoplasms/radiotherapy , Mouth Neoplasms/physiopathology , Mouth Neoplasms/radiotherapy , Osseointegration
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