1.
Pediatr Nephrol
; 8(4): 489-91, 1994 Aug.
Article
in English
| MEDLINE
| ID: mdl-7947045
ABSTRACT
Two children who developed acute renal failure in the immediate post-renal transplantation period are presented. Each was immunosuppressed with cyclosporin and was also receiving oral acyclovir for prophylaxis against cytomegalovirus infection. Renal biopsy findings suggested drug toxicity. Discontinuation of acyclovir coincided with reversal of renal impairment. As cyclosporin levels were at the lower end of the therapeutic range, we believe acyclovir to be the likely causative agent.
Subject(s)
Acute Kidney Injury/chemically induced , Acyclovir/adverse effects , Kidney Transplantation , Acute Kidney Injury/pathology , Acute Kidney Injury/physiopathology , Acyclovir/therapeutic use , Administration, Oral , Adolescent , Biopsy , Child , Cytomegalovirus Infections/prevention & control , Female , Humans , Immunosuppressive Agents/therapeutic use , Kidney/pathology , Male , Premedication
2.
Ann Rheum Dis
; 32(3): 278-9, 1973 May.
Article
in English
| MEDLINE
| ID: mdl-4715549