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1.
Anesth Analg ; 111(4): 992-5, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20675412

ABSTRACT

Timely recognition and surgical decompression are crucial to minimize risk of permanent neurologic deficit from epidural hematoma. We present the case of a patient who developed acute back pain, sensory deficit, and ascending weakness 9 days after removal of a labor epidural catheter. Magnetic resonance imaging revealed a heterogeneous fluid collection extending from C6-7 through the lumbar region, with cord deformity at T9-11. Decompression laminectomy was performed within 4 hours of symptom onset. Twelve hours later, her motor function had fully recovered. Subsequent anatomic and hematologic workup was inconclusive. This presentation is atypical given the delayed presentation of symptoms after epidural placement.


Subject(s)
Analgesia, Epidural/adverse effects , Catheterization/adverse effects , Hematoma, Epidural, Spinal/diagnosis , Hematoma, Epidural, Spinal/etiology , Adult , Analgesia, Epidural/instrumentation , Female , Hematoma, Epidural, Spinal/surgery , Humans , Pregnancy , Time Factors
2.
Anesth Analg ; 103(5): 1147-54, 2006 Nov.
Article in English | MEDLINE | ID: mdl-17056947

ABSTRACT

Cigarette smokers have a greater risk of respiratory complications during anesthesia compared with nonsmokers. It is not known whether the relative pungency of an inhaled anesthetic further contributes to the smokers' increased rate of such complications. In the present study, we tested whether the use of a more pungent anesthetic (desflurane) would result in a higher rate of coughing, breath holding, laryngospasm, or desaturation among patients who smoke. We randomly assigned 110 smokers to anesthesia with desflurane (n = 55) or sevoflurane (n = 55), administered via a laryngeal mask airway. Five patients (9%) receiving desflurane and nine patients (16%) receiving sevoflurane coughed (P = 0.39). Most coughing occurred during induction (33%) or emergence (56%), in the setting of airway manipulation and low anesthetic concentration. The rate of breath holding, laryngospasm, and desaturation was similar between those receiving desflurane versus sevoflurane. A retrospective comparison of this cohort of 110 smokers to a previous group consisting of 100 nonsmokers and 27 smokers receiving an identical anesthetic regimen indicates that cigarette smoking, but not choice of anesthetic, places patients at increased risk of respiratory complications.


Subject(s)
Cough/physiopathology , Isoflurane/analogs & derivatives , Laryngeal Masks , Methyl Ethers/administration & dosage , Smoking/physiopathology , Adult , Cough/epidemiology , Cough/etiology , Desflurane , Female , Humans , Isoflurane/administration & dosage , Laryngeal Masks/adverse effects , Male , Middle Aged , Retrospective Studies , Sevoflurane , Smoking/adverse effects
3.
Anesth Analg ; 100(3): 697-700, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15728054

ABSTRACT

Patients given a more soluble inhaled anesthetic usually take longer to awaken from anesthesia than do patients given a less soluble anesthetic. In the present study, we tested whether such a delay in awakening was also associated with a delay in restoration of protective airway reflexes. Patients were randomly assigned to receive desflurane (n = 31) or sevoflurane (n = 33) via a laryngeal mask airway. Demographics did not differ between groups. The average minimum alveolar anesthetic concentration fraction for both groups was 0.62, and the mean (+/-sd) minimum alveolar anesthetic concentration hours was 1.00 +/- 0.68 for desflurane versus 0.95 +/- 0.57 for sevoflurane, although more patients given sevoflurane also received regional anesthesia (17 for sevoflurane and 8 for desflurane). The time from stopping anesthetic administration to appropriate response to command was longer after sevoflurane (5.5 +/- 3.1 versus 3.4 +/- 1.9 min; P < 0.01). In addition, the time from first response to command to ability to swallow 20 mL of water without coughing or drooling was longer after sevoflurane. At 2 min after responding to command, all patients given desflurane were able to swallow without coughing or drooling, whereas 55% of patients given sevoflurane coughed and/or drooled (P < 0.001). At 6 min after responding to command, 18% of patients given sevoflurane still could not swallow without coughing or drooling (P < 0.05). We conclude that desflurane allows an earlier return of protective airway reflexes.


Subject(s)
Anesthesia Recovery Period , Anesthetics, Inhalation/pharmacology , Isoflurane/analogs & derivatives , Isoflurane/pharmacology , Methyl Ethers/pharmacology , Reflex , Adult , Aged , Body Mass Index , Desflurane , Female , Humans , Male , Middle Aged , Sevoflurane
5.
Anesth Analg ; 96(4): 1191-1192, 2003 Apr.
Article in English | MEDLINE | ID: mdl-12651683

ABSTRACT

IMPLICATIONS: We report a case of upper airway obstruction after subclavian perivascular block in a patient with a preexisting unrecognized paralyzed vocal cord on the opposite side. We discuss the incidence of vocal cord paralysis after subclavian perivascular block and the risk of airway compromise if contralateral vocal cord paralysis is known or suspected.


Subject(s)
Brachial Plexus , Nerve Block/adverse effects , Respiratory Tract Diseases/chemically induced , Vocal Cord Paralysis/chemically induced , Aged , Anesthetics, Local/adverse effects , Bupivacaine/adverse effects , Carcinoma, Squamous Cell/surgery , Epinephrine/adverse effects , Female , Humans , Oxygen Inhalation Therapy , Respiratory Sounds/drug effects , Respiratory Tract Diseases/physiopathology , Tongue Neoplasms/surgery , Vasoconstrictor Agents/adverse effects , Vocal Cord Paralysis/physiopathology
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