ABSTRACT
OBJECTIVE: To report the case of a female who presented in childhood with symptoms and signs of hyperandrogenism secondary to an extraovarian steroid cell tumor. DESIGN: Case report. SETTING: Endocrine investigation unit of a university teaching hospital. PATIENT(S): An 11-year-old female presented with symptoms and signs of hyperandrogenism. INTERVENTION(S): Ultrasonography, MRI imaging, bilateral adrenal and ovarian venous sampling, laparoscopy, and laparotomy. MAIN OUTCOME MEASURE(S): Ultrasonography, laboratory tests. RESULT(S): Hyperandrogenism was due to an extraovarian steroid cell tumor located in the broad ligament. The tumor was successfully removed at laparotomy with biochemical and clinical resolution of the hyperandrogenism. CONCLUSION(S): Extraovarian steroid cell tumor is a rare cause of hyperandrogenism.
Subject(s)
Broad Ligament/pathology , Neoplasms, Gonadal Tissue/pathology , Soft Tissue Neoplasms/pathology , Virilism/etiology , Androgens/metabolism , Child , Female , Humans , Neoplasms, Gonadal Tissue/metabolism , Ovary , Soft Tissue Neoplasms/metabolismABSTRACT
Hungry bone syndrome is a complication of parathyroid surgery where the correction of primary hyperparathyroidism is associated with rapid bone remineralization, causing severe and prolonged hypocalcaemia [1]. We present a case of hungry bones where although there was rapid bone formation, the serum calcium was maintained within normal limits owing to the development of secondary hyperparathyroidism.