1.
Chem Commun (Camb)
; 57(5): 615-618, 2021 Jan 21.
Article
in English
| MEDLINE
| ID: mdl-33346255
ABSTRACT
We developed a superior class of light-activatable molecular beacons with photo-tethered loop regions. Two simple modifications and probe cyclisation prevent the molecular beacon from hybridising with the target RNA before light-activation. Full activity of the molecular beacon is elicited upon illumination with 365 nm light.