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1.
Phys Rev Lett ; 132(15): 155101, 2024 Apr 12.
Article in English | MEDLINE | ID: mdl-38682996

ABSTRACT

The sheared-flow-stabilized Z pinch concept has been studied extensively and is able to produce fusion-relevant plasma parameters along with neutron production over several microseconds. We present here elevated electron temperature results spatially and temporally coincident with the plasma neutron source. An optical Thomson scattering apparatus designed for the FuZE device measures temperatures in the range of 1-3 keV on the axis of the device, 20 cm downstream of the nose cone. The 17-fiber system measures the radial profiles of the electron temperature. Scanning the laser time with respect to the neutron pulse time over a series of discharges allows the reconstruction of the T_{e} temporal response, confirming that the electron temperature peaks simultaneously with the neutron output, as well as the pinch current and inductive voltage generated within the plasma. Comparison to spectroscopic ion temperature measurements suggests a plasma in thermal equilibrium. The elevated T_{e} confirms the presence of a plasma assembled on axis, and indicates limited radiative losses, demonstrating a basis for scaling this device toward net gain fusion conditions.

2.
Rev Sci Instrum ; 94(2): 023508, 2023 Feb 01.
Article in English | MEDLINE | ID: mdl-36859043

ABSTRACT

We report the first optical Thomson scattering measurements inside a high electron temperature (≳1 keV) and moderate electron density (mid 1016 cm-3) plasma. This diagnostic has been built to provide critical plasma parameters, such as electron temperature and density, for Advanced Research Projects Agency-Energy-supported fusion-energy concepts. It uses an 8 J laser at 532 nm in 1.5 ns to measure the high frequency feature of the Thomson scattering profile at 17 locations along the probe axis. It is able to measure electron density from 5 × 1017 cm-3 to several 1019 cm-3 and electron temperatures from tens of eV to several keV. Here, we describe the design, deployment, and analysis on the sheared flow stabilized Z-pinch machine at Zap Energy named FuZE. The probe beam is aimed at an axial distance of 20 cm from the central electrode and is timed within the temporal envelope of neutron emission. The high temperature and moderate density plasmas generated on FuZE lie in an unconventional regime for Thomson scattering as they are between tokamaks and laser-produced plasmas. We described the analysis considerations in this regime, show that the electron density was below 5 × 1016 cm-3 at all times during these measurements, and present a sample shot where the inferred electron temperature varied from 167 ± 16 eV to 700 ± 85 eV over 1.6 cm.

3.
Phys Rev E ; 105(5-2): 055206, 2022 May.
Article in English | MEDLINE | ID: mdl-35706166

ABSTRACT

Laser-accelerated proton beams are applicable to several research areas within high-energy density science, including warm dense matter generation, proton radiography, and inertial confinement fusion, which all involve transport of the beam through matter. We report on experimental measurements of intense proton beam transport through plastic foam blocks. The intense proton beam was accelerated by the 10ps, 700J OMEGA EP laser irradiating a curved foil target, and focused by an attached hollow cone. The protons then entered the foam block of density 0.38g/cm^{3} and thickness 0.55 or 1.00mm. At the rear of the foam block, a Cu layer revealed the cross section of the intense beam via proton- and hot electron-induced Cu-K_{α} emission. Images of x-ray emission show a bright spot on the rear Cu film indicative of a forward-directed beam without major breakup. 2D fluid-PIC simulations of the transport were conducted using a unique multi-injection source model incorporating energy-dependent beam divergence. Along with postprocessed calculations of the Cu-K_{α} emission profile, simulations showed that protons retain their ballistic transport through the foam and are able to heat the foam up to several keV in temperature. The total experimental emission profile for the 1.0mm foam agrees qualitatively with the simulated profile, suggesting that the protons indeed retain their beamlike qualities.

4.
Fungal Genet Biol ; 144: 103439, 2020 11.
Article in English | MEDLINE | ID: mdl-32768603

ABSTRACT

In this research we report that the sepG1 mutation in Aspergillus nidulans resides in gene AN9463, which is predicted to encode an IQGAP orthologue. The genetic lesion is predicted to result in a G-to-R substitution at residue 1637 of the 1737-residue protein in a highly conserved region of the RasGAP-C-terminal (RGCT) domain. When grown at restrictive temperature, strains expressing the sepGG1637R (sepG1) allele are aseptate, with reduced colony growth and aberrantly formed conidiophores. The aseptate condition can be replicated by deletion of AN9463 or by downregulating its expression via introduced promoters. The mutation does not prevent assembly of a cortical contractile actomyosin ring (CAR) at putative septation sites, but tight compaction of the rings is impaired and the rings fail to constrict. Both GFP::SepG wild type and the GFP-tagged product of the sepG1 allele localize to the CAR at both permissive and restrictive temperatures. Downregulation of myoB (encoding the A. nidulans type-II myosin heavy chain) does not prevent formation of SepG rings at septation sites, but filamentous actin is required for CAR localization of SepG and MyoB. We identify fourteen probable IQ-motifs (EF-hand protein binding sites) in the predicted SepG sequence. Two of the A. nidulans EF-hand proteins, myosin essential light chain (AnCdc4) and myosin regulatory light chain (MrlC), colocalize with SepG and MyoB at all stages of CAR formation and constriction. However, calmodulin (CamA) appears at septation sites only after the CAR has become fully compacted. When expression of sepG is downregulated, leaving MyoB as the sole IQ-motif protein in the pre-compaction CAR, both MrlC and AnCdc4 continue to associate with the forming CAR. When myoB expression is downregulated, leaving SepG as the sole IQ-motif protein in the CAR, AnCdc4 association with the forming CAR continues but MrlC fails to associate. This supports a model in which the IQ motifs of MyoB bind both MrlC and AnCdc4, while the IQ motifs of SepG bind only AnCdc4. Downregulation of either mrlC or Ancdc4 results in an aseptate phenotype, but has no effect on association of either SepG or MyoB with the CAR.


Subject(s)
Actomyosin/genetics , Aspergillus nidulans/genetics , Contractile Proteins/genetics , ras GTPase-Activating Proteins/genetics , Actin Cytoskeleton/genetics , Binding Sites , Calmodulin/genetics , Constriction , Cytokinesis/genetics , Mutation/genetics , Myosin Light Chains/genetics , Myosin Type II/genetics , Protein Binding/genetics
5.
Sci Rep ; 10(1): 9415, 2020 Jun 10.
Article in English | MEDLINE | ID: mdl-32523004

ABSTRACT

Proton beams driven by chirped pulse amplified lasers have multi-picosecond duration and can isochorically and volumetrically heat material samples, potentially providing an approach for creating samples of warm dense matter with conditions not present on Earth. Envisioned on a larger scale, they could heat fusion fuel to achieve ignition. We have shown in an experiment that a kilojoule-class, multi-picosecond short pulse laser is particularly effective for heating materials. The proton beam can be focussed via target design to achieve exceptionally high flux, important for the applications mentioned. The laser irradiated spherically curved diamond-like-carbon targets with intensity 4 × 1018 W/cm2, producing proton beams with 3 MeV slope temperature. A Cu witness foil was positioned behind the curved target, and the gap between was either empty or spanned with a structure. With a structured target, the total emission of Cu Kα fluorescence was increased 18 fold and the emission profile was consistent with a tightly focussed beam. Transverse proton radiography probed the target with ps order temporal and 10 µm spatial resolution, revealing the fast-acting focussing electric field. Complementary particle-in-cell simulations show how the structures funnel protons to the tight focus. The beam of protons and neutralizing electrons induce the bright Kα emission observed and heat the Cu to 100 eV.

6.
Rev Sci Instrum ; 90(8): 083302, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31472598

ABSTRACT

Calibrated diagnostics for energetic particle detection allow for the systematic study of charged particle sources. The Fujifilm BAS-TR imaging plate (IP) is a reusable phosphorescent detector for radiation applications such as x-ray and particle beam detection. The BAS-TR IP has been absolutely calibrated to many low-Z (low proton number) ions, and extending these calibrations to the mid-Z regime is beneficial for the study of laser-driven ion sources. The Texas Petawatt Laser was used to generate energetic ions from a 100 nm titanium foil, and charge states Ti10+ through Ti12+, ranging from 6 to 27 MeV, were analyzed for calibration. A plastic detector of CR-39 with evenly placed slots was mounted in front of the IP to count the number of ions that correspond with the IP levels of photo-stimulated luminescence (PSL). A response curve was fitted to the data, yielding a model of the PSL signal vs ion energy. Comparisons to other published response curves are also presented, illustrating the trend of PSL/nucleon decreasing with increasing ion mass.

7.
Phys Rev Lett ; 122(15): 155002, 2019 Apr 19.
Article in English | MEDLINE | ID: mdl-31050520

ABSTRACT

The rapid heating of a thin titanium foil by a high intensity, subpicosecond laser is studied by using a 2D narrow-band x-ray imaging and x-ray spectroscopy. A novel monochromatic imaging diagnostic tuned to 4.51 keV Ti Kα was used to successfully visualize a significantly ionized area (⟨Z⟩>17±1) of the solid density plasma to be within a ∼35 µm diameter spot in the transverse direction and 2 µm in depth. The measurements and a 2D collisional particle-in-cell simulation reveal that, in the fast isochoric heating of solid foil by an intense laser light, such a high ionization state in solid titanium is achieved by thermal diffusion from the hot preplasma in a few picoseconds after the pulse ends. The shift of Kα and formation of a missing Kα cannot be explained with the present atomic physics model. The measured Kα image is reproduced only when a phenomenological model for the Kα shift with a threshold ionization of ⟨Z⟩=17 is included. This work reveals how the ionization state and electron temperature of the isochorically heated nonequilibrium plasma are independently increased.

8.
Phys Rev Lett ; 122(13): 135001, 2019 Apr 05.
Article in English | MEDLINE | ID: mdl-31012637

ABSTRACT

The sheared-flow stabilized Z pinch has demonstrated long-lived plasmas with fusion-relevant parameters. We present the first experimental results demonstrating sustained, quasi-steady-state neutron production from the fusion Z-pinch experiment, operated with a mixture of 20% deuterium/80% hydrogen by pressure. Neutron emissions lasting approximately 5 µs are reproducibly observed with pinch currents of approximately 200 kA during an approximately 16 µs period of plasma quiescence. The average neutron yield is estimated to be (1.25±0.45)×10^{5} neutrons/pulse and scales with the square of the deuterium concentration. Coincident with the neutron signal, plasma temperatures of 1-2 keV and densities of approximately 10^{17} cm^{-3} with 0.3 cm pinch radii are measured with fully integrated diagnostics.

9.
Sci Rep ; 8(1): 17538, 2018 Dec 03.
Article in English | MEDLINE | ID: mdl-30510273

ABSTRACT

Intense lasers can accelerate protons in sufficient numbers and energy that the resulting beam can heat materials to exotic warm (10 s of eV temperature) states. Here we show with experimental data that a laser-driven proton beam focused onto a target heated it in a localized spot with size strongly dependent upon material and as small as 35 µm radius. Simulations indicate that cold stopping power values cannot model the intense proton beam transport in solid targets well enough to match the large differences observed. In the experiment a 74 J, 670 fs laser drove a focusing proton beam that transported through different thicknesses of solid Mylar, Al, Cu or Au, eventually heating a rear, thin, Au witness layer. The XUV emission seen from the rear of the Au indicated a clear dependence of proton beam transport upon atomic number, Z, of the transport layer: a larger and brighter emission spot was measured after proton transport through the lower Z foils even with equal mass density for supposed equivalent proton stopping range. Beam transport dynamics pertaining to the observed heated spot were investigated numerically with a particle-in-cell (PIC) code. In simulations protons moving through an Al transport layer result in higher Au temperature responsible for higher Au radiant emittance compared to a Cu transport case. The inferred finding that proton stopping varies with temperature in different materials, considerably changing the beam heating profile, can guide applications seeking to controllably heat targets with intense proton beams.

10.
Rev Sci Instrum ; 89(10): 10F122, 2018 Oct.
Article in English | MEDLINE | ID: mdl-30399802

ABSTRACT

Here we propose a pump-probe X-ray absorption spectroscopy temperature measurement technique appropriate for matter having temperature in the range of 10 to a few 100 eV and density up to solid density. Atomic modeling simulations indicate that for various low- to mid-Z materials in this range the energy and optical depth of bound-bound and bound-free absorption features are sensitive to temperature. We discuss sample thickness and tamp layer considerations. A series of experimental investigations was carried out using a range of laser parameters with pulse duration ≤5 ps and various pure and alloyed materials to identify backlighter sources suitable for the technique.

11.
Epidemiol Infect ; 146(8): 954-960, 2018 06.
Article in English | MEDLINE | ID: mdl-29655383

ABSTRACT

Studies estimating the human health impact of the foodborne disease often include estimates of the number of gastroenteritis hospitalisations. The aims of this study were to examine the degree to which hospital discharge data underreport hospitalisations due to bacterial gastroenteritis and to estimate the frequency of stool sample submission among patients presenting with gastroenteritis. Using linked laboratory and hospital discharge data from a healthcare organisation and its affiliated hospital, we examined the International Classification of Disease (ICD-9-CM) diagnosis codes assigned to hospitalised adults with culture-confirmed Campylobacter, Salmonella, or Escherichia coli O157 infections and determined the frequency of stool sample submission. Among 138 hospitalised patients with culture-confirmed infections, 43% of Campylobacter patients, 56% of Salmonella patients and 35% of E. coli O157 patients had that pathogen-specific code listed on the discharge record. Among patients without their infection listed as a diagnosis, 65% were assigned a nonspecific gastroenteritis code. Submitting a specimen for culture ⩾3 days before discharge was significantly associated with having the pathogen-specific diagnosis listed. Of 6181 patients assigned a nonspecific gastroenteritis code, 69% had submitted a stool sample for bacterial culture. This study can be used to understand differences and adjust for the underreporting and underdiagnosed of Campylobacter, Salmonella and E. coli O157 in hospital discharge and surveillance data, respectively.


Subject(s)
Campylobacter Infections/epidemiology , Escherichia coli Infections/epidemiology , Foodborne Diseases/epidemiology , Gastroenteritis/epidemiology , Hospitalization/statistics & numerical data , Population Surveillance/methods , Salmonella Infections/epidemiology , Campylobacter/physiology , Campylobacter Infections/microbiology , Escherichia coli Infections/microbiology , Escherichia coli O157/physiology , Foodborne Diseases/microbiology , Gastroenteritis/microbiology , Salmonella/physiology , Salmonella Infections/microbiology , Wisconsin/epidemiology
12.
Rev Sci Instrum ; 88(6): 063502, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28668008

ABSTRACT

Simultaneous monochromatic crystal imaging at 4.5 and 8.0 keV with x-rays produced by a single short-pulse laser is presented. A layered target consisting of thin foils of titanium and copper glued together is irradiated by the 50 TW Leopard short-pulse laser housed at the Nevada Terawatt Facility. Laser-accelerated MeV fast electrons transmitting through the target induce Kα fluorescence from both foils. Two energy-selective curved crystals in the imaging diagnostic form separate monochromatic images on a single imaging detector. The experiment demonstrates simultaneous two-color monochromatic imaging of the foils on a single detector as well as Kα x-ray production at two different photon energies with a single laser beam. Application of the diagnostic technique to x-ray radiography of a high density plasma is also presented.

13.
Phys Rev Lett ; 118(20): 205001, 2017 May 19.
Article in English | MEDLINE | ID: mdl-28581770

ABSTRACT

Collimated transport of ultrahigh intensity electron current was observed in cold and in laser-shocked vitreous carbon, in agreement with simulation predictions. The fast electron beams were created by coupling high-intensity and high-contrast laser pulses onto copper-coated cones drilled into the carbon samples. The guiding mechanism-observed only for times before the shock breakout at the inner cone tip-is due to self-generated resistive magnetic fields of ∼0.5-1 kT arising from the intense currents of fast electrons in vitreous carbon, by virtue of its specific high resistivity over the range of explored background temperatures. The spatial distribution of the electron beams, injected through the samples at different stages of compression, was characterized by side-on imaging of hard x-ray fluorescence.

14.
Rev Sci Instrum ; 88(4): 043110, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28456236

ABSTRACT

We have built an absolutely calibrated, highly efficient, Bragg crystal spectrometer in von Hamos geometry. This zinc von Hamos spectrometer uses a crystal made from highly oriented pyrolytic graphite that is cylindrically bent along the non-dispersive axis. It is tuned to measure x-ray spectra in the 7-10 keV range and has been designed to be used on a Ten Inch Manipulator for the Omega and OmegaEP target chambers at the Laboratory for Laser Energetics in Rochester, USA. Significant shielding strategies and fluorescence mitigation have been implemented in addition to an imaging plate detector making it well suited for experiments in high-intensity environments. Here we present the design and absolute calibration as well as mosaicity and integrated reflectivity measurements.

15.
Phys Rev Lett ; 116(15): 155001, 2016 04 15.
Article in English | MEDLINE | ID: mdl-27127972

ABSTRACT

The interaction of a multipicosecond, kilojoule laser pulse with a surface of a solid target has been shown to produce electrons with energies far beyond the free-electron ponderomotive limit m_{e}c^{2}a_{0}^{2}/2. Particle-in-cell simulations indicate that an increase in the pulse duration from 1 to 10 ps leads to the formation of a low-density shelf (about 10% of the critical density). The shelf extends over 100 µm toward the vacuum side, with a nonstationary potential barrier forming in that area. Electrons reflected from the barrier gain superponderomotive energy from the potential. Some electrons experience an even greater energy gain due to ponderomotive acceleration when their "dephasing rate" R=γ-p_{x}/m_{e}c drops well below unity, thus increasing acceleration by a factor of 1/R. Both 1D and 2D simulations indicate that these mechanisms are responsible for the generation of extensive thermal distributions with T_{e}>10 MeV and a high-energy cutoff of hundreds of MeV.

16.
Phys Rev Lett ; 114(9): 095004, 2015 Mar 06.
Article in English | MEDLINE | ID: mdl-25793822

ABSTRACT

Energy loss in the transport of a beam of relativistic electrons in warm dense aluminum is measured in the regime of ultrahigh electron beam current density over 2×10^{11} A/cm^{2} (time averaged). The samples are heated by shock compression. Comparing to undriven cold solid targets, the roles of the different initial resistivity and of the transient resistivity (upon target heating during electron transport) are directly observable in the experimental data, and are reproduced by a comprehensive set of simulations describing the hydrodynamics of the shock compression and electron beam generation and transport. We measured a 19% increase in electron resistive energy loss in warm dense compared to cold solid samples of identical areal mass.

17.
Article in English | MEDLINE | ID: mdl-26764843

ABSTRACT

The consequences of small scale-length precursor plasmas on high-intensity laser-driven relativistic electrons are studied via experiments and simulations. Longer scale-length plasmas are shown to dramatically increase the efficiency of electron acceleration, yet, if too long, they reduce the coupling of these electrons into the solid target. Evidence for the existence of an optimal plasma scale-length is presented and estimated to be from 1 to 5µm. Experiments on the Trident laser (I=5×10(19)W/cm(2)) diagnosed via Kα emission from Cu wires attached to Au cones are quantitively reproduced using 2D particle-in-cell simulations that capture the full temporal and spatial scale of the nonlinear laser interaction and electron transport. The simulations indicate that 32%±8%(6.5%±2%) of the laser energy is coupled into electrons of all energies (1-3 MeV) reaching the inner cone tip and that, with an optimized scale-length, this could increase to 35% (9%).

18.
Nat Commun ; 5: 5785, 2014 Dec 12.
Article in English | MEDLINE | ID: mdl-25503788

ABSTRACT

The advent of high-intensity lasers enables us to recreate and study the behaviour of matter under the extreme densities and pressures that exist in many astrophysical objects. It may also enable us to develop a power source based on laser-driven nuclear fusion. Achieving such conditions usually requires a target that is highly uniform and spherically symmetric. Here we show that it is possible to generate high densities in a so-called fast-ignition target that consists of a thin shell whose spherical symmetry is interrupted by the inclusion of a metal cone. Using picosecond-time-resolved X-ray radiography, we show that we can achieve areal densities in excess of 300 mg cm(-2) with a nanosecond-duration compression pulse--the highest areal density ever reported for a cone-in-shell target. Such densities are high enough to stop MeV electrons, which is necessary for igniting the fuel with a subsequent picosecond pulse focused into the resulting plasma.

19.
Article in English | MEDLINE | ID: mdl-24730954

ABSTRACT

Refluxing of fast electrons generated by high-intensity, short-pulse lasers was investigated by measuring electron-induced Kα x rays from a buried tracer layer. Using planar foils of Au/Cu/CH, the 150-J, 0.7-ps TITAN short-pulse laser was focused on the gold foil to generate fast electrons and the 3-ns, 300-J long pulse beam irradiated on the CH side to create expanding plasma as a conducting medium. By delaying the short-pulse beam timing from the long pulse laser irradiation, the plasma size was varied to change electron refluxing in the target rear. The total yields and two-dimensional images of 8.05-keV Cu-Kα x ray were recorded with an x-ray spectrometer and two monochromatic crystal imagers. The measurements show that the integrated yields decrease by a factor of 10 from refluxing to the nonrefluxing limit. Similar radial profiles of the Kα images in the rear were observed at all delays. Hybrid-particle-in-cell simulations using plasma profiles calculated by a radiation-hydrodynamic code HYDRA agree well with the measured Kα yields. The simulations suggest that conducting plasma with the size of ∼300 µm in the laser direction and ∼600 µm in the lateral direction at the density of 2 × 1020 1/cm3 is sufficiently large to prevent electrons from refluxing in the target. The parameters found in this study can be useful in designing experiments utilizing a Kα x-ray source in refluxing regime or a tracer layer in nonrefluxing regime.

20.
Rev Sci Instrum ; 84(2): 023704, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23464215

ABSTRACT

A Kirkpatrick-Baez X-ray microscope has been developed for use on the Titan laser facility at the Lawrence Livermore National Laboratory in Fast Ignition experiments. It was developed as a broadband alternative to narrow band Bragg crystal imagers for imaging Kα emission from tracer layers. A re-entrant design is employed which allows for alignment from outside the chamber. The mirrors are coated with Pt and operate at a grazing incident angle of 0.5° providing higher resolution than an equal brightness pinhole and sufficient bandwidth to image thermally shifted characteristic Kα emission from heated Cu tracer layers in Fast Ignition experiments. The superpolished substrates (<1 Å rms roughness) had a final visible wavelength roughness of 1.7 Å after coating, and exhibited a reflectivity corresponding to an X-ray wavelength roughness of 7 ± 1 Å. A unique feature of this design is that during experiments, the unfiltered direct signal along with the one-dimensional reflections are retained on the detector in order to enable a live indication of alignment and incident angle. The broad spectral window from 4 to 9 keV enables simultaneous observation of emission from several spectral regions of interest, which has been demonstrated to be particularly useful for cone-wire targets. An experimentally measured resolution of 15 µm has been obtained at the center of the field of view.

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