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1.
Surg Neurol ; 9(3): 211-3, 1978 Mar.
Article in English | MEDLINE | ID: mdl-635770

ABSTRACT

Inasmuch as prolonged halothane anesthesia is often associated with hypotension, the effects of pressor agents possibly employed to adjust this hypotension on cerebral blood flow are of interest. In dogs, after prolonged halothane anesthesia, there was a marked difference in the effects of phenylephrine and angiotensin on cerebral blood flow at dosages which promote moderate rises in blood pressure. Phenylephrine had no effect whereas angiotensin had a significantly enhancing effect on cerebral blood flow.


Subject(s)
Anesthesia, Inhalation , Angiotensin II/pharmacology , Blood Pressure/drug effects , Cerebrovascular Circulation/drug effects , Halothane , Animals , Dogs , Homeostasis , Phenylephrine/pharmacology
5.
Surg Neurol ; 5(3): 147-9, 1976 Mar.
Article in English | MEDLINE | ID: mdl-1257884

ABSTRACT

Significant reduction of experimentally induced cerebral infarction was associated in the canine model with the administration of pentobarbital at one hour postocclusion but not thereafter.


Subject(s)
Cerebrovascular Disorders/prevention & control , Disease Models, Animal , Animals , Dogs , Time Factors
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