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1.
Br J Rheumatol ; 27(5): 399-402, 1988 Oct.
Article in English | MEDLINE | ID: mdl-3179631

ABSTRACT

A patient with definite polymyositis responded clinically to prednisolone in combination with azathioprine, with improvement in muscle strength and normalization of muscle enzyme levels. After 7 weeks' treatment the patient developed chest pain and fatal ventricular arrhythmias. An autopsy showed inflammatory myocarditis, but marked improvement in the skeletal muscle histology. This case illustrates that myocarditis may be a late complication of polymyositis despite immunosuppressive therapy.


Subject(s)
Arrhythmias, Cardiac/etiology , Myocarditis/complications , Myositis/complications , Acute Disease , Aged , Female , Humans , Myositis/drug therapy
2.
Gut ; 22(6): 452-5, 1981 Jun.
Article in English | MEDLINE | ID: mdl-6114898

ABSTRACT

Sperm analysis of 21 patients taking sulphasalazine for inflammatory bowel disease revealed that 86% had abnormal semen analysis and 72% had oligospermia.


Subject(s)
Infertility, Male/chemically induced , Sulfasalazine/adverse effects , Adolescent , Adult , Colitis, Ulcerative/drug therapy , Crohn Disease/drug therapy , Humans , Infertility, Male/epidemiology , Male , Middle Aged , Spermatozoa/drug effects , Sulfasalazine/therapeutic use
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