ABSTRACT
The medical records of 34 dogs (median age, eight years) with colorectal mucosal lesions were reviewed. Hematochezia was the most common (82%) presenting sign. Most dogs (79%) presented with solitary masses located in the rectum. After histological review, 12 masses were classified as adenomatous polyps and 22 as carcinoma in situ. Recurrence of clinical signs were common (41%), and malignant transformation of the tumor was documented in 18% of the cases. A higher recurrence rate and malignant transformation occurred in dogs presented with multiple masses or diffuse disease and in dogs initially diagnosed with carcinoma in situ.
Subject(s)
Adenoma/veterinary , Carcinoma in Situ/veterinary , Colorectal Neoplasms/veterinary , Dog Diseases/diagnosis , Polyps/veterinary , Adenoma/diagnosis , Adenoma/pathology , Animals , Carcinoma in Situ/diagnosis , Carcinoma in Situ/pathology , Cell Transformation, Neoplastic/pathology , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/pathology , Dog Diseases/epidemiology , Dog Diseases/pathology , Dogs , Female , Male , Neoplasm Recurrence, Local/veterinary , Polyps/diagnosis , Polyps/pathology , Prevalence , Retrospective StudiesABSTRACT
Globule leukocyte tumor involving the distal portion of the jejunum and proximal portion of the ileum caused chronic vomiting and weight loss in a 3-year-old cat. The intestinal mass was resected during exploratory laparotomy. The histologic appearance of the mass was characterized by inclusion of numerous intracytoplasmic eosinophilic granules. Similar cells were found in the mesenteric lymph node and were suggestive of metastasis. Tumor recurrence was not detected until 13.5 months after the surgery. The malignant but slow-growing nature of this tumor allowed a disease-free interval that exceeded 1 year, despite incomplete tumor resection.
Subject(s)
Cat Diseases , Granular Cell Tumor/veterinary , Ileal Neoplasms/veterinary , Jejunal Neoplasms/veterinary , Anastomosis, Surgical/veterinary , Animals , Cat Diseases/diagnosis , Cat Diseases/pathology , Cat Diseases/surgery , Cats , Cysts/diagnosis , Cysts/pathology , Cysts/surgery , Cysts/veterinary , Cytoplasmic Granules/pathology , Female , Follow-Up Studies , Granular Cell Tumor/diagnosis , Granular Cell Tumor/pathology , Granular Cell Tumor/surgery , Ileal Neoplasms/diagnosis , Ileal Neoplasms/pathology , Ileal Neoplasms/surgery , Jejunal Neoplasms/diagnosis , Jejunal Neoplasms/pathology , Jejunal Neoplasms/surgery , Lymphatic Metastasis , Neoplasm Recurrence, Local/veterinary , Postoperative Complications/veterinaryABSTRACT
Half-pin (type 1) external skeletal fixators with four, three, and two fixation pins and an intramedullary pin, and four-pin external skeletal fixators without an intramedullary pin were applied to prepared canine femurs. Load to failure, load to yield, safe load, and stiffness under compressive and torsional loads were calculated. When tested in compression, all measurements for the four-pin fixators with an intramedullary pin were significantly higher than for the two-pin fixators with an intramedullary pin. The values for all parameters except load to yield were significantly higher for the four-pin fixators with an intramedullary pin than for the four-pin fixators without an intramedullary pin. When tested in torsion, all measurements for the four-pin fixators with an intramedullary pin were significantly higher than for the two or three-pin fixators with an intramedullary pin.
