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1.
Occup Environ Med ; 65(2): 141-6, 2008 Feb.
Article in English | MEDLINE | ID: mdl-17704194

ABSTRACT

OBJECTIVES: To investigate patterns of use of personal protective equipment (PPE) to reduce pesticide exposure in a sample of Australian farmers and also to assess the influence of possible predictive factors. METHODS: A cross-sectional survey of 1102 farmers recruited through the Victorian Farmers Federation (VFF) was conducted. A written questionnaire was filled out by participants at VFF meetings attended by a visiting research assistant. Participants answered questions about frequency of pesticide use and PPE items they usually used when doing two different pesticide-related tasks, mixing and application, of each of four classes of pesticides. They also answered questions about personal characteristics, farm characteristics, farming activities, career and health. RESULTS: Nearly all surveyed farmers had ever used pesticides, and over 87% had used Herbicides or Animal Health Products in the previous 12 months. Non-use of PPE was frequently reported, with up to 10-40% of farmers routinely using no PPE at all when using pesticides. Across all pesticide classes, PPE use was higher for pesticide mixing than for application. In multivariate analyses PPE use appeared to be most strongly associated with younger age and farm chemical training. CONCLUSIONS: PPE use across all pesticide classes was poor, indicating the possibility of clinically significant pesticide exposure in many farmers. Given that PPE use was found to be associated with farm chemical training, the authors suggest that training is likely to be an important intervention for reducing farmers' pesticide exposure. Poor uptake of farm chemical training by farmers and the aging farming workforce are causes for concern in the light of these findings.


Subject(s)
Agricultural Workers' Diseases/prevention & control , Agriculture , Occupational Health , Pesticides , Protective Devices , Adult , Aged , Aged, 80 and over , Australia , Cross-Sectional Studies , Edible Grain , Female , Gloves, Protective , Humans , Logistic Models , Male , Middle Aged , Occupational Exposure , Protective Clothing , Respiratory Protective Devices , Surveys and Questionnaires
2.
Xenobiotica ; 22(5): 599-607, 1992 May.
Article in English | MEDLINE | ID: mdl-1413875

ABSTRACT

1. Phosphine progressively converts oxyhaemoglobin to methaemoglobin and hemichrome species, with the product formed being time- and concentration-dependent. 2. The reaction of phosphine with oxyhaemoglobin leads to the formation of phosphite and phosphate. 3. Incubation of rat erythrocytes with various concentrations of phosphine results in the progressive uptake of phosphine by the erythrocytes in a temperature-dependent first-order process. 4. Uptake of phosphine by erythrocytes causes crenation, but conversion of oxyhaemoglobin to methaemoglobin and hemichrome could not be demonstrated.


Subject(s)
Erythrocytes/drug effects , Hemoglobins/drug effects , Insecticides/toxicity , Phosphines/toxicity , Animals , Biotransformation , Erythrocytes/metabolism , Hemoglobins/metabolism , Hemolysis , Oxyhemoglobins/metabolism , Phosphines/blood , Phosphines/pharmacokinetics , Rats , Rats, Sprague-Dawley , Spectrophotometry
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