ABSTRACT
BACKGROUND: Multiple currently accepted treatments for non melanoma skin cancer (NMSC) are now available. PURPOSE: To present multimodality treatment for NMSCs and to report any side effects or recurrence during three years follow-up period. MATERIAL AND METHODS: This is a prospective study including 120 patients with NMSCs. Patients were subjected to different treatment modalities with follow-up for three years. RESULTS: 103 Patients (85.8%) were treated by surgery with or without post operative radiotherapy, 8 patients (5%) received only radiation therapy, 7 patients (5.8%) treated by shave excision followed by medical treatment (intralesional interferon for 3 months, systemic retinoids and cyclo-oxygenase inhibitor for 6 months), and 2 patients (1.7%) escaped the treatment. All patients treated by shave excision followed by medical treatment showed complete healing of all lesions 6 months after completing the course of treatment. CONCLUSION: Alternatives to the surgical management of NMSC may be preferred under certain circumstances. KEY WORDS: BCC - Interferon - Retinoids - SCC.
ABSTRACT
PURPOSE: The aim of this study was to reevaluate the role and effectiveness of pedicled myocutanous and myofascial flaps in reconstruction after resection of head and neck cancer. PATIENTS AND METHODS: This study represents the authors own experience using pedicled myocutanous and myofascial flaps in reconstruction after resection of malignant tumors of different sites in the head and neck. The study included 121 patients with head and neck cancer operated upon at the National Cancer Institute, Cairo University and Alminia Cancer Center over 3 years duration, between July 2005 and the end of July 2008. Four types of flaps were used namely the Pectoralis major (Group I), lower trapezius (Group II), Latissimus dorsi (Group III), and the temporalis ((Group IV) flaps. Utility of the different types of these flaps was reevaluated in terms of indications, advantages, and postoperative complications. RESULTS: This study included 121 patients, 83 males and 38 females. The mean age was 56 years (range, 14- 65 years). Oral malignancies represented most of the cases (71 cases). Pectoralis major myocutaneous (PMMC) flap was the most commonly used flap (84 cases) and its main indication was oral and pharyngeal defects. Lower trapezius and Latissimus dorsi myocutaneous flaps were used in 14 and 12 cases respectively. Their main indications were tumors in the occiput, ear pinna, parotid and neck regions. The Latissimus dorsi myocutaneous flap was also used for reconstruction of oral and pharyngeal defects in 7 female patients with large breasts and for salvage reconstruction after failure of reconstruction by (PMMC) flap in one patient and for reconstruction after excision of local recurrence on top of previous (PMMC) flap in another patient. Temporalis myofascial flap was used in 12 cases and the main indication was orbital defects. The overall postoperative complications was 19.8% (24/121). It was 20% (17/84) in group I, 28.6% (4/14) in group II, and 25% (3/12) in group III. No flap related complications were reported in group IV. All complications were successfully managed except for one case in (Group I), in which a major flap loss developed and was successfully salvaged by pedicled latissimus dorsi myocutaneous flap. CONCLUSION: Pedicled myocutanous and myofascial flaps are still indicated in composite head and neck reconstruction. Their reliability, safety, and high degree of resistance to infection make them essential specially the (PMMC) flap previously described as the spare wheel of head and neck reconstructive surgery. It is suitable for lateral mandibular defects in edentulous patients and in partial pharyngeal defects in irradiated patients. Other pedicled myocutaneous flaps are still valid in certain occasions and sites. KEY WORDS: Head and neck cancer - Pectoralis major - Trapezius - Latissimus dorsi - Temporalis myocutaneous - Myofascial flaps - Reconstruction.
