ABSTRACT
The fermentation-group is largely employed to produce pharmaceuticals by means of biotechnology techniques. The operative functions of these plants are surely kept under control by the validation process, while its cleaning is less investigated. The aim of this work is the cleaning validation of a fermentation-group. Furthermore, Standard Operative Procedures (SOPs) have been validated relating to the production necessities and to the allowed safety limits.
Subject(s)
Biotechnology/methods , Fermentation , Biotechnology/standards , Reproducibility of ResultsABSTRACT
The results of a research about dental age assessment and its relationships with skeletal age are presented. Using a method based on eight stages of tooth formation, as visualized on panoramic radiography, a sample of 327 patients between 3 and 13 and 1/2 was investigated. Data were analyzed splitting into sex and skeletal Class groups and following the steps: 1) description: by charts and percentages; 2) analysis: by contingency tables and independence statistical tests; 3) synthesis of association: by a proper index.