1.
Biochem Pharmacol
; 29(4): 597-601, 1980 Feb 15.
Article
in English
| MEDLINE
| ID: mdl-6245656
Subject(s)
Anti-Bacterial Agents/adverse effects , Hearing Disorders/chemically induced , Membranes, Artificial , Phosphatidylinositols , Aminoglycosides/adverse effects , Animals , Chemical Phenomena , Chemistry, Physical , Cochlea/drug effects , Guinea Pigs , Male , Membrane Potentials/drug effects , Surface Properties
2.
Acta Otolaryngol
; 88(1-2): 56-60, 1979.
Article
in English
| MEDLINE
| ID: mdl-474121
ABSTRACT
The influence of neomycin and streptomycin on the calcium metabolism of the otolithic membranes was investigated in the guinea pig. After chronic treatment with either drug, animals were injected intraperitoneally with radioactive calcium. Retention of calcium in the serum was unaffected by drug treatment, as was the incorporation of radioactivity into bone (femur and otic capsule). Both drugs inhibited the calcium uptake into saccular and utricular otolithic membranes by 30 to 40%.
