ABSTRACT
BACKGROUND: Acute aortic syndrome is the modern term that includes aortic dissection, intramural hematoma, and symptomatic aortic ulcer. Iatrogenic coronary artery dissection extending to the aorta during percutaneous coronary intervention is a very rare but life-threatening complication. Despite some reports of spontaneous recovery, most of these patients are treated surgically as a spontaneous aortic dissection, especially if there is a complication of the aortic lesion. CASE REPORT: A 52-year-old white female was submitted to an angioplasty in the right coronary without success and the procedure was complicated by a dissection in aortic root with progressive extension to the ascending aorta. This lesion deformed the aortic valve, leaving it with an acute moderate regurgitation. Because of current use of clopidogrel and clinical stability of the patient, the local Heart Team decided to withdrawn this antiplatelet for 5 days before surgery despite the risk related to the aortic syndrome. A new echocardiogram 3 days later showed that the hematoma was reabsorbed with improvement of the aortic insufficiency. An angiotomography confirmed the reabsorption of the hematoma. The surgery was canceled and the patient was maintained in a conservative treatment and discharged. Seventeen months later, she was re-evaluated and was still asymptomatic without aortic regurgitation in the echocardiogram and showing progressive regression of the aortic hematoma in the tomography. CONCLUSIONS: Despite the conservative treatment, this case of iatrogenic aortic dissection complicated by an acute aortic regurgitation had a good evolution in a follow-up of 17 months.
Subject(s)
Acute Coronary Syndrome/surgery , Aortic Aneurysm, Thoracic/etiology , Aortic Dissection/etiology , Aortic Valve Insufficiency/complications , Percutaneous Coronary Intervention/adverse effects , Acute Disease , Aortic Dissection/diagnosis , Aortic Aneurysm, Thoracic/diagnosis , Aortic Valve Insufficiency/diagnosis , Coronary Angiography , Echocardiography, Transesophageal , Female , Humans , Middle Aged , Remission, Spontaneous , Syndrome , Tomography, X-Ray ComputedABSTRACT
O presente caso relata uma anomalia congênita (1:14.000 necropsias) e de difícil diagnóstico, visto que os portadores dessa anomalia, geralmente são assintomaticos: a agenesia do pericárdio. O diagnóstico baseado no tripé: radiografia de tórax, ecodopplercardiograma e tomografia computadorizada ou ressonância magnética de tórax deve ser sempre lembrando, uma vez que a patologia oferece risco de evolução para evento cardíaco agudo potencialmente letal, quando de sua apresentação parcial.
Subject(s)
Humans , Male , Child , Heart Defects, Congenital/genetics , Echocardiography/methods , Echocardiography , Magnetic Resonance Spectroscopy , Pericardium/abnormalities , Radiography, Thoracic , TomographySubject(s)
Echocardiography , Echocardiography/instrumentation , Echocardiography/standards , Echocardiography/methods , Echocardiography, Transesophageal/instrumentation , Echocardiography, Transesophageal/standards , Humans , Ultrasonography, Prenatal/instrumentation , Ultrasonography, Prenatal/standardsABSTRACT
Arterial compliance is determined by structural factors, such as collagen and elastin, and functional factors, such as vasoactive neurohormones. To determine whether angiotensin II contributes to decreased arterial compliance in patients with heart failure, this study tested the hypothesis that administration of an angiotensin-converting enzyme inhibitor improves arterial compliance. Arterial compliance and stiffness were determined by measuring carotid artery diameter, using high-resolution duplex ultrasonography, and blood pressure in 23 patients with heart failure secondary to idiopathic dilated cardiomyopathy. Measurements were made before and after intravenous administration of enalaprilat (1 mg) or vehicle. Arterial compliance was inversely related to both baseline plasma angiotensin II (r = -0.52; P = 0.015) and angiotensin-converting enzyme concentrations (r = -0.45; P = 0.041). During isobaric conditions, enalaprilat increased carotid artery compliance from 3.0 +/- 0.4 to 5.0 +/- 0.4 x 10(-10) N(-1). m(4) (P = 0.001) and decreased the carotid artery stiffness index from 17.5 +/- 1.8 to 10.1 +/- 0.6 units (P = 0.001), whereas the vehicle had no effect. Thus angiotensin II is associated with reduced carotid arterial compliance in patients with congestive heart failure, and angiotensin-converting enzyme inhibition improves arterial elastic properties. This favorable effect on the pulsatile component of afterload may contribute to the improvement in left ventricular performance that occurs in patients with heart failure treated with angiotensin-converting enzyme inhibitors.
Subject(s)
Angiotensin II/metabolism , Angiotensin-Converting Enzyme Inhibitors/administration & dosage , Enalaprilat/administration & dosage , Heart Failure/drug therapy , Heart Failure/physiopathology , Adult , Brachial Artery/drug effects , Brachial Artery/physiology , Carotid Arteries/drug effects , Carotid Arteries/physiology , Compliance/drug effects , Elasticity/drug effects , Female , Humans , Male , Manometry , Middle AgedABSTRACT
Eighty patients with tight and pliable mitral stenosis were randomized in a prospective trial comparing percutaneous balloon valvuloplasty and open commissurotomy. Mitral valve area increased significantly in both groups immediately after the procedures. However, a decrease in mitral valve area occurred in both groups at 6, 12 and 24 months during the follow-up. There was no death in either group. Two patients had significant mitral regurgitation after percutaneous balloon valvuloplasty. After 24 months, all patients in the commissurotomy group and 97.4% of the patients in the balloon valvuloplasty group were in New York Heart Association functional class I or II.
Subject(s)
Cardiac Surgical Procedures , Cardiopulmonary Bypass , Catheterization , Mitral Valve Stenosis/surgery , Adolescent , Adult , Echocardiography, Doppler , Female , Follow-Up Studies , Humans , Male , Middle Aged , Mitral Valve Stenosis/diagnostic imaging , Mitral Valve Stenosis/physiopathology , Outcome Assessment, Health Care , Prospective Studies , Severity of Illness Index , Time FactorsABSTRACT
A 21-year-old white man presented with cardiogenic shock and refractory pulmonary congestion. At the transthoracic echocardiogram a subvalvar left ventricular aneurysm of the inferior wall with severe mitral regurgitation was observed. The outcome was favorable after surgical correction of the mitral regurgitation and of the subvalvar aneurysm. We emphasize that, whenever possible, valvar repair is better than mitral replacement, since annulus tissue fragility causes suturing of the mitral prosthesis to be difficult.
Subject(s)
Humans , Male , Adult , Heart Aneurysm/complications , Mitral Valve Insufficiency/etiology , Electrocardiography , Heart Aneurysm/surgery , Mitral Valve Insufficiency/surgery , Heart VentriclesABSTRACT
OBJETIVO - Avaliar os efeitos agudos da ibopamina (IBO) sobre a mecânica e a contrabilidade miocárdica em pacientes com insuficiência cardíaca congestiva (ICC)refratária secundária à cardiomiopatia dilatada idiopática.MÉTODOS- Foram estudados 10 pacientes (idade= 43+-7anos) do sexo masculino, em ritmo sinusal, com cardiomiopatia dilatada idiopática e ICC refratária.Foram realizados estudos ecocardiográficos e hemodinâmicos (cateter micro-tip) simultâneos, antes (basal) e após (20,40 e 60min) à administraçäo de um comprimido de 200mg de IBO.Para cada fase obtidas as relaçöes pressäo/diâmetro e esforço/de formaçäo do ventrículo esquerdo (VE).A partir destas relaçöes foram analisados:frequência cardíaca (FC-bpm), débito cardíaco (DC-L/m), pressäo diastólica final (PDF-mmHg); fraçäo de encurtamento (D por cento); elastância máxima (E máx - mmHg/cm/s);esforços sistólico final (ESF-g/cm2) e diastólito final (EDF-g/cm2); rididez da cavidade (Kp-mmHg/cm) e do músculo cardíaco (Km-g/cm2);e tempo da constante de relaxamento (Tau-ms).RESULTADOS- Na condiçäo basal e aos 20,40 e 60min após a administraçäo da IBO, näo houve variaçäo significante na FC (99+-7;99+-8e99+-10), e foram observados aumentos signifacantes do DC (4,13+-1,28;4,95+-1,38;5,13+-1,86;5,18+-1,57), do D por cento (13,7+-2,4;15,4+-2,8;15,9+-1,8;16,1+-2,0), e da E máx (14,8+-3,2;16+-3,6;17,7+-4,2;17,6+-4,2).Houve mudanças significativas, com aumento transitório inicial seguido de diminuiçäo da PDF ( 26,3+-4,2;30,6+-6,4;24,6+-5,6;22,3+-4,6) do EDF (79,7+-22,8;91,7+-29,6;79+-31;63+-17,3) e do Kp (27,2+-12,6;60+-26,7;27,9+-11,7;28+-11).CONCLUSAO - A IBO produziu efeito benéfico na funçäo sistólica e diastólica do VE, bem como aumentou a contratilidade em pacientes com insuficiência cardíaca severa devido à cardiomiopatia dilatada idiopática
Purpose - The effects of ibopamine (IBO) on left ventricular (LV) mechanics and contractility have not been described. The aim of this study was to test the hypothesis that IBO has a contractile effect at a dose of 200mg. Methods - Ten male patients (43±7 years) with refractory heart failure due to idiopathic dilated cardiomyopathy were studied. The patients were submitted to simultaneous echo-Doppler and hemodynamic (microtip catheter) studies, before (B) and after (20, 40 and 60 minutes) a dose of 200mg of IBO. LV pressure/diameter and stress/strain relations were obtained. Subsequently, heart rate (HR-bpm), cardiac output (CO-L/m), end-diastolic pressure (EDPmmHg); fractional shortening (FS-%); maximal elastance (Emax-mmHg/cm/s); end systolic (ESS-g/cm2) and enddiastolic (EDS-g/cm2) stress; chamber (Kp-mmHg/cm) andmuscle (Km-g/cm2) stiffness, and the time of constant relaxation (Tau-ms) were analyzed. Results - Results were presented as mean ± standard deviation for conditions before and after IBO (20, 40 and 60 minutes) respectively. There was no change in HR (99±7; 100±7; 99±8; 99±10). Significant increa ses were observed in CO (4.13±1.28; 4.95±1.38; 5.13±1.86;5.18±1.57), FS (13.7±2.4; 15.4±2.8; 15.9±1.8; 16.1±2.0), and Emax (14.8±3.2; 16±3.6; 17.7±4.2; 17.6±4.2). A transient (20 minutes) increase followed by a decrease (40 and 60 minutes) ocurred in EDP (26.3±4.2; 30.6±6.4; 24.6±5.6; 22.3±4.6), EDS (79.7±22.8; 91.7±29.6; 79±31; 63±17.3), and Kp (27.2±12.6; 60±26.7; 27.9±11.7; 28.1±11). Conclusion - IBO has a beneficial effect on LV systolic and diastolic function as well as on contractility in patients with heart failure due to idiopathic dilated cardiomyopathy
Subject(s)
Humans , Male , Adult , Middle Aged , Cardiomyopathies , Myocardial Contraction , Ventricular Function , Heart FailureABSTRACT
Objetivo - Avaliar os resultados da valvoplastia mitral por cateter baläo (VMCB) a curto e a médio prazos. Métodos - Cento e quatro procedimentos em 103 pacientes, 89 (87%) mulheres e média etária de 33 anos. O diagnóstico foi estenose mitral (EM) em 95 (91%), reestenose mitral em 7 (7%) e bioprótese estenótica em 2(2%). Doze pacientes (10%) estavam em classe funcional (CF) II (NYHA), 73 (70%) em CF III e 19 (18%) em CF IV. Noventa e três (89%) estavam em ritmo sinusal, 10 (10%) em fibrilaçäo atrial e 1 (1%) em ritmo funcional. Em 99% dos casos a técnica empregada foi transeptal. Resultados hemodinâmicos comparativos entre pré X pós VMCB imediato foram: área valvar mitral (cm2) 0,75 ñ 0,27 x 1,68 ñ 0m48 (p < 0,0001), gradiente AE-VE médio (mmHg) 19,52 ñ 8,03 x 5,44 ñ 4,38 p < 0,0001); pressäo média de AE (mmHg) 24,72 ñ 8,76 x 9,63 ñ 6,11 (p < 0,0001); índice cardíaco (L/min/m*) 2,55 ñ 0,69 x 2,92 ñ 0,77 (p < 0,0001); pressäo média de AP (mmHg) 40,17 ñ 16,52 x 25,65 ñ 13,77 (p < 0,0001). Ao ecocardiograma os resultados comparativos entre pré-VMCB, pós-VMCB, controle de 6 meses e 12 meses pós-VMCB foram respectivamente: área valvar mitral (cm*) 0,89 ñ 0,23 x 1,87 ñ 0,41 x 1,72 ñ 0,43 x 1,64 ñ 0,44 e gradiente transvalvar mitral (mmHg) 13,12 ñ 4,66 x 6,44 ñ 2,93 x 7,72 ñ 3,24 x 8,30 ñ 4,17. Houve um óbito imediato pós-VMCB em paciente portadora de tromboembolismo pulmonar, 4 (4%) pacientes com insuficiência mitral importante (1 óbito no pós-operatório imediato) e 2 pacientes com reestenose mitral. Conclusäo - A VMCB mostra-se método eficaz e seguro ocorrendo persistência de bons resultados no período de 1 ano de acompanhamento
Purpose - To evaluate percutaneous mitral balloon valvuloplasty (PMBV) results immediately and one yearfollow-up. Methods - One hundred andfour procedures in 103 patients, 89 (87%) were women and mean age was 33. Ninety five (91%) had mitral stenosis, 7 (7%) mitral restenosis and 2 (2%) stenotic bioprosthesis. Twelve (10%) patients were in functional class (FC) II (NYHA), 73 (70%) in FC III and 19 (18%) in FC IV. Ninety three (89%) were in sinusal rhythm, 10 (10%) had atrialfibrilation and 1 (1%) junctional rhythm. In 99% cases the transeptal access was used. Results - The comparative haemodinamic results late x immediately after-PMBV were mitral valve area (cm2) 0.75 ± 0.27 x 1.68 ±0.48 (p < 0.0001), gradiente AE-VE average (mmHg) 19.52 ± 8.03 x 5.44 ± 4.38 (p < 0.0001); average pressure AE (mmHg) 24.72 ± 8.76 x 9.63 ± 6.11 (p < 0.0001), cardiac inde x (L/ min/m2) 2.55 ± 0.69 x 2.92 ± 0.77 (p < 0.0001); average pressure PA (mmHg) 40.17 ± 16.52 x 25.65 ± 13.77 (p < 0.0001). The echocardiography results pré-PMBV, post-PMBV, 6 and 12 months after PMBV were respectively: mitral valve area (cm2) 0.89 ± 0.23 x 1.87 ± 0.41 x 1.72 ± 0.43 x 1.64 ± 0.44 and mitral transvalvar gradient (mmHg) 13.12 ± 4.66 x 6.44 ± 2.93 x 7.72 ± 3.24 x 8.30 ± 4.17. There was one death immediately after-PMBV in a patient with pulmonar thromboembolism. Four (4%) had severe mitral regurgitation and went to surgery (1 death). There were 2 mitral reestenosis. Conclusion - For selected patients PMBVis a safe method and the good results are maintained in 1 year follow-up
