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1.
Med Mal Infect ; 39(12): 906-8, 2009 Dec.
Article in French | MEDLINE | ID: mdl-19118962

ABSTRACT

INTRODUCTION: Metronidazole is a widely prescribed treatment for amoebic and anaerobic germ infections. Its neurologic toxicity is rare but can be serious. CASE REPORT: We report the case of a 27-year-old male patient, treated with metronidazole for a cerebral abscess. He presented with a cerebellar syndrome and peripheral neuropathy at a cumulative metronidazole dose of 60g. The MRI aspect of the cerebellar lesions in addition to their reversibility after treatment cessation led to the diagnosis of metronidazole induced neurologic toxicity. CONCLUSION: The occurrence of neurologic disorders in patients treated with metronidazole must suggest drug toxicity and lead to cessation of treatment.


Subject(s)
Brain Abscess/drug therapy , Cerebellar Diseases/chemically induced , Metronidazole/adverse effects , Peripheral Nervous System Diseases/chemically induced , Adult , Cerebellar Diseases/diagnosis , Consciousness Disorders/chemically induced , Humans , Magnetic Resonance Imaging , Male , Metronidazole/therapeutic use , Sensation Disorders/chemically induced
2.
Ann Saudi Med ; 21(1-2): 49-52, 2001.
Article in English | MEDLINE | ID: mdl-17264590
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