1.
Med Mal Infect
; 39(12): 906-8, 2009 Dec.
Article
in French
| MEDLINE
| ID: mdl-19118962
ABSTRACT
INTRODUCTION: Metronidazole is a widely prescribed treatment for amoebic and anaerobic germ infections. Its neurologic toxicity is rare but can be serious. CASE REPORT: We report the case of a 27-year-old male patient, treated with metronidazole for a cerebral abscess. He presented with a cerebellar syndrome and peripheral neuropathy at a cumulative metronidazole dose of 60g. The MRI aspect of the cerebellar lesions in addition to their reversibility after treatment cessation led to the diagnosis of metronidazole induced neurologic toxicity. CONCLUSION: The occurrence of neurologic disorders in patients treated with metronidazole must suggest drug toxicity and lead to cessation of treatment.
Subject(s)
Brain Abscess/drug therapy , Cerebellar Diseases/chemically induced , Metronidazole/adverse effects , Peripheral Nervous System Diseases/chemically induced , Adult , Cerebellar Diseases/diagnosis , Consciousness Disorders/chemically induced , Humans , Magnetic Resonance Imaging , Male , Metronidazole/therapeutic use , Sensation Disorders/chemically induced
2.
3.
Presse Med
; 29(33): 1842, 2000 Nov 04.
Article
in French
| MEDLINE
| ID: mdl-11109442