ABSTRACT
BACKGROUND: Helicobacter pylori (H. pylori) is the main etiologic agent of chronic gastritis and it is an important cause of gastric damage. The celiac disease can affect the morphology and the function of the gastrointestinal tract from the stomach to the colon and it is frequently associated with chronic gastritis. AIM: to assess the presence of H. pylori in gastric biopsies and in feces of pediatric patients with celiac disease and to relate it with the symptoms. PATIENTS AND METHODS: Pediatric patients with celiac disease attending the Gastroenterology Service at the "Avelino Castelán" Hospital in Resistencia (Argentina) were included in the study. Gastric biopsies samples were obtained by endoscopy for histological studies, the symptoms and socio-epidemiological characteristics were recorded and the polimerase chain reaction(PCR) was applied in feces in order to detect the presence of H. pylori. RESULTS: Thirty one patients with celiac disease were studied (16 female and 15 male; age range:1-14 years; median 6.7 years); 14 (45.2%) were positive for H. pylori in gastric biopsy and among them, only 2 (14.2%) were positive for H. pylori in stool samples. There were not significant differences between symptoms between H. pylori positive and negative patients. CONCLUSION: 45.2% of the patients with celiac disease were infected by H. pylori. There was no correlation between the frequencies of bacterial detection in feces and in gastric biopsies. The clinical manifestations of celiac disease did not increase in children infected with H. pylori.
Subject(s)
Celiac Disease/microbiology , Feces/microbiology , Helicobacter pylori/isolation & purification , Stomach/microbiology , Stomach/pathology , Adolescent , Biopsy , Celiac Disease/diagnosis , Child , Child, Preschool , Female , Humans , Infant , Male , Prospective StudiesABSTRACT
This study is a multifactorial analysis of the risk factors for low birthweight in a group of newborns in an urban area of Brazil. A total of 1023 infants born in four maternity units in Salvador, Bahia, between July 1987 and February 1988 were included in the study. The sources of information were clinical histories and interviews with the mothers in the maternity units. The analysis was by means of logistic regression. In the final model the risk factors were the following: maternal age less than 21 years or more than 35; gestational age less than 38 weeks; unfavorable outcome of an earlier pregnancy; interval of 12 months or less since prior birth; tobacco smoking; and hypertension. The population attributable risk values for the risk factors included in the final model are presented. These factors should be used to identify pregnant women at high risk of giving birth to a low-birthweight baby, in order to provide them with more prenatal care.
Subject(s)
Infant, Low Birth Weight , Brazil , Humans , Infant, Newborn , Regression Analysis , Risk FactorsABSTRACT
Con el objeto de determinar las caracteristicas clinico-evoluativas y terapeuticas los casos de histiocitosis X vistos en el Instituto Nacional de Pediatria DIF, de la ciudad de Mexico, se revisa el periodo 1970-1979. Se encuentran 45 casos de histiocitosis S (frecuencia 1:4333 pacientes pediatricos; y 1:388 pacientes dermatologicos) en sus tres formas clinicas: Enfermedad de Letterer-Siwe 15. Enfermedad de Hand-Schuller-Christian 22, y granuloma eosinofilo del hueso 8. Habia lesiones cutaneas en el 57% de los casos, pero su frecuencia variada con las formas clinicas Asi estaban presentes en el 93% de los casos de E.L.S. y en el 63% de los E.H.S.C.; y ausentes en los de granuloma eosinofilo del hueso.Los cuadros simulando dermatitis seborreica fueron los habituales, siguiendoles las purpuras, intertrigos y ulceraciones. En ningun paciente estas lesiones precedieron al cuadro clinico general
Subject(s)
Infant , Child, Preschool , Child , Humans , Male , Female , Histiocytosis, Langerhans-Cell , Skin ManifestationsABSTRACT
Con el objeto de determinar las caracteristicas clinico-evoluativas y terapeuticas los casos de histiocitosis X vistos en el Instituto Nacional de Pediatria DIF, de la ciudad de Mexico, se revisa el periodo 1970-1979. Se encuentran 45 casos de histiocitosis S (frecuencia 1:4333 pacientes pediatricos; y 1:388 pacientes dermatologicos) en sus tres formas clinicas: Enfermedad de Letterer-Siwe 15. Enfermedad de Hand-Schuller-Christian 22, y granuloma eosinofilo del hueso 8. Habia lesiones cutaneas en el 57% de los casos, pero su frecuencia variada con las formas clinicas Asi estaban presentes en el 93% de los casos de E.L.S. y en el 63% de los E.H.S.C.; y ausentes en los de granuloma eosinofilo del hueso.Los cuadros simulando dermatitis seborreica fueron los habituales, siguiendoles las purpuras, intertrigos y ulceraciones. En ningun paciente estas lesiones precedieron al cuadro clinico general
