ABSTRACT
Gastroesophageal reflux disease is a widespread among population in economically developed countries including Russia. It was analyzed the results of 34 903 endoscopic examinations of upper gastrointestinal tract in ethnically and socially homogeneous population of Leningrad region with symptoms of gastric dispepsia. Procedures were performed for the period 2007-2013. Prevalence of erosive esophagitis was 4.9%. Peptic esophageal strictures due to chronic reflux-associated inflammation were revealed in 0.2% of examined patients (3.7% of patients with erosive esophagitis). Obtained data allow to considergastroesophageal reflux disease as a socially significant problem in Russia requiring close attention and further study.
Subject(s)
Esophageal Stenosis/epidemiology , Esophagitis, Peptic/epidemiology , Peptic Ulcer/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Endoscopy, Gastrointestinal , Esophageal Stenosis/diagnosis , Esophageal Stenosis/etiology , Esophagitis, Peptic/diagnosis , Esophagus/pathology , Female , Humans , Male , Middle Aged , Peptic Ulcer/complications , Peptic Ulcer/diagnosis , Prevalence , Retrospective Studies , Russia/epidemiology , Young AdultABSTRACT
The article presents an analysis of 34.903 esophagoscopy results performed for population of Leningrad region at the period from 2007 to 2013. A prevalence of erosive esophagitis was 4.9%, peptic strictures--0.18%, columnar-celled metaplasias--1.43% and esophageal adenocarcinoma--0.645%. The data obtained showed a high prevalence of GERD-associated syndromes with injury of mucous coat of esophagus in the local population of Russians.
Subject(s)
Esophageal Diseases , Esophagoscopy/statistics & numerical data , Esophagus/pathology , Gastroesophageal Reflux , Adult , Esophageal Diseases/diagnosis , Esophageal Diseases/epidemiology , Esophageal Diseases/etiology , Female , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/epidemiology , Humans , Male , Prevalence , Russia/epidemiologyABSTRACT
This article presents the analysis of 24384 endoscopic investigations of the upper gastrointestinal tract in population of Leningrad region with symptoms of dyspepsia during the period 2007-2011.The results revealed erosive esophagitis in 5.4%, peptic strictures of the esophagus--0.2%, the columnar-lining esophagus (Barrett's esophagus)--1.1%, and esophageal adenocarcinoma--0.045%. This data shows a high prevalence of esophageal complications of GERD in a local population of Russians.
Subject(s)
Adenocarcinoma , Barrett Esophagus , Esophageal Neoplasms , Esophagitis, Peptic , Gastroesophageal Reflux , Adenocarcinoma/epidemiology , Adenocarcinoma/etiology , Barrett Esophagus/epidemiology , Barrett Esophagus/ethnology , Esophageal Neoplasms/epidemiology , Esophageal Neoplasms/etiology , Esophagitis, Peptic/epidemiology , Esophagitis, Peptic/etiology , Female , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/epidemiology , Humans , Male , Russia/epidemiologyABSTRACT
The article presents an analysis of results of 24 384 endoscopic examinations of the upper gastrointestinal tract in population of the Leningrad oblast with symptoms of gastric dyspepsia during the period from 2007 to 2011. The detection of the columnar-celled metaplasia was 1.1%, adenocarcinoma of the esophagus--0.045%. Esophageal adenocarcinoma occurred in 3.95% of cases of the column-celled esophagus. Barrett's esophagus was revealed in males more often than in women (56.5% and 54.5% respectively). The peak incidence of esophageal adenocarcinoma in males was at the age from 46 to 60 years (36.4% of patients), in females--from 61 to 75 years (27.3% of patients). Intestinal metaplasia was detected in 72.7% of cases with esophageal adenocarcinoma: The diagnosis of long and short segment of column-celled esophagus revealed no significant difference in the development of esophageal adenocarcinoma.
Subject(s)
Adenocarcinoma/pathology , Barrett Esophagus/pathology , Endoscopy, Digestive System/methods , Esophageal Neoplasms/pathology , Esophagus/pathology , Adult , Aged , Barrett Esophagus/epidemiology , Diagnosis, Differential , Disease Progression , Esophageal Neoplasms/epidemiology , Female , Humans , Incidence , Male , Metaplasia/epidemiology , Metaplasia/pathology , Middle Aged , Retrospective Studies , Russia/epidemiologyABSTRACT
The pathomorphological picture of 17 lungs resected for various forms of chronic nonspecific diseases of the lungs was compared with results of preoperative radioisotope studies. It was found that greater degree of decreased capillary blood flow in the lungs was followed by progressive growth of destructive, sclerotic alterations in the altered part of the lung, rearrangement of the vascular bed from the network type to the major vessel type took place. Similar comparison can help the clinic physician to disclose the real picture of the pathological process in the lungs.
Subject(s)
Bronchiectasis/surgery , Lung/pathology , Pneumonia/surgery , Pulmonary Fibrosis/surgery , Bronchiectasis/diagnostic imaging , Bronchiectasis/pathology , Chronic Disease , Female , Humans , Lung/diagnostic imaging , Male , Pneumonia/diagnostic imaging , Pneumonia/pathology , Pulmonary Fibrosis/diagnostic imaging , Pulmonary Fibrosis/pathology , Radionuclide Imaging , SclerosisABSTRACT
A typical case of Niemann-Pick disease in a 22-month boy is presented. The disease was associated with a CNS lesion, as well as with the impairment of macrophagal-histiocytic system. The study of native material in the polarized light with subsequent confirmation by histochemical methods is considered as a method of choice for diagnosis of lingering diseases beginning in the postnatal period and with a suspicion of thesaurismosis, sphingomyelinosis, in particular.
