ABSTRACT
Results of surgical treatment of 1085 patients with lumbar disc herniation operated from 1999 to 2009 were analyzed. It was shown, that frequency of LIII-IV and LIV-V herniated discs increases and that of LV-SI, decreases with ageing.
Subject(s)
Intervertebral Disc Displacement/epidemiology , Intervertebral Disc Displacement/surgery , Adolescent , Adult , Age Factors , Aged , Female , Humans , Male , Middle Aged , Retrospective StudiesSubject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Cyclooxygenase Inhibitors/therapeutic use , Ketorolac/therapeutic use , Pain, Postoperative/prevention & control , Piroxicam/analogs & derivatives , Adolescent , Adult , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/economics , Cyclooxygenase Inhibitors/administration & dosage , Cyclooxygenase Inhibitors/economics , Female , Humans , Ketorolac/administration & dosage , Ketorolac/economics , Male , Middle Aged , Models, Economic , Neurosurgery , Pain Measurement , Pain, Postoperative/diagnosis , Pain, Postoperative/drug therapy , Pain, Postoperative/economics , Patient Selection , Piroxicam/administration & dosage , Piroxicam/economics , Piroxicam/therapeutic use , Time Factors , Treatment OutcomeSubject(s)
Gastroenterology , General Surgery , Antineoplastic Agents/therapeutic use , Chemotherapy, Adjuvant , Cholecystectomy, Laparoscopic , Combined Modality Therapy , Commonwealth of Independent States , Gallbladder Diseases/diagnosis , Gallbladder Diseases/surgery , Humans , Liver Diseases/diagnosis , Liver Diseases/surgery , Liver Neoplasms/diagnosis , Liver Neoplasms/drug therapy , Liver Neoplasms/surgery , Pancreatic Diseases/diagnosis , Pancreatic Diseases/surgery , Postoperative Care , Postoperative Complications , RussiaSubject(s)
Abscess/etiology , Appendicitis/complications , Cecal Diseases/etiology , Shock, Septic/etiology , Abscess/diagnosis , Abscess/surgery , Acute Disease , Adult , Aged , Appendicitis/diagnosis , Appendicitis/surgery , Cecal Diseases/diagnosis , Cecal Diseases/surgery , Colectomy , Female , Gangrene , Humans , Male , Reoperation , Shock, Septic/diagnosis , Shock, Septic/surgerySubject(s)
Ileal Diseases/complications , Intestinal Obstruction/etiology , Peritonitis/etiology , Shock, Septic/etiology , Sigmoid Diseases/complications , Acute Disease , Colon, Sigmoid/pathology , Colon, Sigmoid/surgery , Combined Modality Therapy , Humans , Ileal Diseases/pathology , Ileal Diseases/surgery , Ileum/pathology , Ileum/surgery , Intestinal Obstruction/pathology , Intestinal Obstruction/surgery , Male , Middle Aged , Necrosis , Peritonitis/pathology , Peritonitis/surgery , Reoperation , Shock, Septic/pathology , Shock, Septic/surgery , Sigmoid Diseases/pathology , Sigmoid Diseases/surgeryABSTRACT
On the basis of experimental and clinical investigations the authors showed immunity depression in complicated forms of cholelithiasis. Thymogene appeared to be efficient for immunocorrection that permitted to lower the frequency of postoperative complications and lethality.
Subject(s)
Adjuvants, Immunologic/therapeutic use , Cholelithiasis/therapy , Dipeptides , Peptides/therapeutic use , Acute Disease , Animals , Antibody Formation/drug effects , Cats , Cholecystectomy , Choledochostomy , Cholelithiasis/complications , Cholelithiasis/immunology , Combined Modality Therapy , Drug Evaluation , Drug Evaluation, Preclinical , Humans , Immunity, Cellular/drug effects , Postoperative Care , Postoperative Complications/prevention & controlABSTRACT
In 165 patients with the different forms of cholelithiasis, a level of the circulating immune complexes (CIC) was measured in the blood serum and bile from the common bile duct at the postoperative period. In associated purulent-resorptive and cholemic intoxication, the CIC level in the blood serum and bile increases. This, in turns, enhances the likelihood of the development of purulent-septic complications at the postoperative period, and requires performance of target immunocorrection.
Subject(s)
Antigen-Antibody Complex/metabolism , Bile/metabolism , Gallstones/metabolism , Postoperative Complications/metabolism , Acute Disease , Chronic Disease , Female , Gallstones/immunology , Gallstones/surgery , Humans , Male , Middle AgedSubject(s)
Adenosine/administration & dosage , Hemodynamics/drug effects , Inosine Diphosphate/administration & dosage , Liver/drug effects , Peritonitis/drug therapy , Animals , Cats , Female , Hemodynamics/physiology , Injections, Intravenous , Liver/physiopathology , Male , Peritonitis/physiopathology , Portal VeinABSTRACT
The authors made an analysis of early operations on 6076 patients. This tactics used in 84.3% of the patients allowed to reduce postoperative lethality up to 2.5%.
Subject(s)
Cholecystectomy/methods , Cholecystitis/surgery , Acute Disease , Aged , Cholecystectomy/mortality , Cholecystitis/mortality , Emergencies , Humans , Middle Aged , Time FactorsABSTRACT
It was determined that tumor necrosis factor (TNF) is capable of decreasing the local brain's blood flow on 45.6% (in the concentration of 6 micrograms/kg); to make a spasm of the pial arteries on 39.6%. In vitro experiments TNF increased the amplitude of the rhythmical and the tonic contractions of the brain's arteries smooth muscles (3.6 X 10(-8) M). The direct action of the TNF in the vascular wall is endothelium-dependent.
Subject(s)
Cerebral Arteries/drug effects , Cerebrovascular Circulation/drug effects , Tumor Necrosis Factor-alpha/pharmacology , Animals , Female , In Vitro Techniques , Male , Muscle Tonus/drug effects , Muscle, Smooth, Vascular/drug effects , Neovascularization, Pathologic , Pia Mater/blood supply , RabbitsABSTRACT
The reactivity and functional heterogeneity of cerebral arteries are maintained by the participation of the endothelium in the regulation of the smooth muscles and by the influence of vasoactive peptides upon the neurotransmitter mechanisms. The initial level of the basal tone plays a major role, too.
