ABSTRACT
INTRODUCTION: Malignant primary tumours occurring in the thorax encompass a large group of tumours which may arise from the lung, mediastinal structures, the pleura or the chest wall. OBSERVATION: We report the case of a 37 year old patient, who presented with left sided chest pain. On clinical examination a right sided chest wall mass was identified. Chest X Ray showed a left sided upper mediastinal opacity, associated with a left sided pleural opacity. Thoracic CT scan revealed a large mass arising from the chest wall and infiltrating the mediastinum associated with a second chest wall mass at the level of the 8(th) and 9(th) right ribs. The biopsy of the chest wall mass revealed it to be a parietal synovialosarcoma. The patient responded to chemotherapy based on ifosfamid and doxorubicin as well as mediastino-pulmonary radiotherapy. There was an improvement in the patient's clinical and radiological state but the patient died by pulmonary embolism after the 3(rd) cause of treatment. CONCLUSION: Chest wall synovialosarcoma has a poor prognosis, however, its chemosensitivity means that treatment may initially be effective.
Subject(s)
Sarcoma, Synovial/pathology , Thoracic Neoplasms/pathology , Thoracic Wall/pathology , Adult , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Chemotherapy, Adjuvant , Chest Pain/etiology , Combined Modality Therapy , Doxorubicin/administration & dosage , Fatal Outcome , Humans , Ifosfamide/administration & dosage , Male , Postoperative Complications , Pulmonary Embolism/complications , Radiotherapy, Adjuvant , Sarcoma, Synovial/drug therapy , Sarcoma, Synovial/radiotherapy , Sarcoma, Synovial/surgery , Thoracic Neoplasms/drug therapy , Thoracic Neoplasms/radiotherapy , Thoracic Neoplasms/surgery , Thoracic Wall/surgery , Tomography, X-Ray ComputedABSTRACT
Idiopathic pulmonary haemosiderosis is a rare disease of unknown etiopathogeny which is characterized by hemoptysis due to alveolar haemorrhage. We report the case of a 16 years-old girl with idiopathic pulmonary haemosiderosis, diagnosed through clinical, radiological, cytological and histopathological data. The finding of myeloperoxydase-anti-neutrophil cytoplasmic antibodies (ANCA) positivity led us to suspect an associated vasculitis which was not further demonstrated.
Subject(s)
Antibodies, Antineutrophil Cytoplasmic/blood , Hemosiderosis/immunology , Lung Diseases/immunology , Adolescent , Anti-Inflammatory Agents/administration & dosage , Anti-Inflammatory Agents/therapeutic use , Biopsy , Enzyme-Linked Immunosorbent Assay , Female , Fluorescent Antibody Technique, Indirect , Follow-Up Studies , Hemoptysis/etiology , Hemorrhage/etiology , Hemosiderosis/diagnosis , Hemosiderosis/diagnostic imaging , Hemosiderosis/drug therapy , Hemosiderosis/pathology , Humans , Lung/pathology , Lung Diseases/diagnosis , Lung Diseases/diagnostic imaging , Lung Diseases/drug therapy , Lung Diseases/pathology , Prednisone/administration & dosage , Prednisone/therapeutic use , Pulmonary Alveoli , Radiography, Thoracic , Time Factors , Treatment OutcomeABSTRACT
INTRODUCTION: Hydatid disease of bone is very rare accounting for 0.5% - 3% of all localisations. CASE REPORT: We report the case of a woman of 30 years who presented with posterior chest pain. The chest radiograph showed an extra-pulmonary mass associated with a lytic rib lesion. Thoracic ultrasound revealed a multiloculated soft tissue and fluid mass. CT scan showed a fluid filled costo-vertebral cyst. MRI identified extension into the spinal canal. Pathological examination of the surgically resected material confirmed the diagnosis. CONCLUSIONS: This observation emphasises the role of MRI in assessing the extent of hydatid cysts of the posterior chest wall and in particular invasion of the spinal canal.
