ABSTRACT
Objetivo: Evaluar la fiabilidad y validez de un cuestionario de calidad de vida en pacientes con cáncer de vejiga no músculo invasivo. Materiales y métodos: Se incluyeron 180 pacientes. Se elaboró un cuestionario de 21 preguntas agrupadas en 5 áreas que los pacientes cumplimentaban. A su vez, los pacientes cumplimentaban el cuestionario Functional Assessment of Cancer Therapy- Bladder Cancer (FACT-BL). Para estudiar la fiabilidad se calculó el coeficiente Alfa de Cronbach y el Índice Kappa. Para estudiar la validez de criterio se estudió, con el coeficiente de correlación de Pearson, la asociación entre las puntuaciones obtenidas por el nuevo cuestionario y el FACT-BL. Para estudiar la validez de constructo (factorial y discriminante) se realizó análisis factorial, comparándose con la «t» de Student, las puntuaciones según características tumorales objetivas de peor calidad de vida (por ejemplo localización en trígono). Resultados: El Alfa de Cronbach fue 0,83 y los Índices Kappa oscilaron entre 0,7 y 1. En el estudio de asociación del nuevo cuestionario y FACT-BL se obtuvo una r = 0,82 para la puntuación global, y entre una r = 0,68 (enfermedad) y una r = 0,97 (vida sexual) en las diferentes dimensiones. En el análisis factorial se obtuvo KMO = 0,77 y test de Barlett p < 0,001. La comparación de las puntuaciones en presencia o ausencia de determinadas características tumorales han obtenido peores resultados de calidad de vida en presencia de las mismas, en la mayoría de ocasiones, estadísticamente significativas (p < 0.05). Conclusión: El cuestionario elaborado para medir la calidad de vida de los pacientes con cáncer de vejiga no músculo invasivo es fiable y válido
Objective: To determine the reliability and validity of a quality-of-life survey for patients with nonmuscle-invasive bladder cancer. Material and methods: A total of 180 patients were included in the study. We developed a survey with 21 questions grouped into 5 areas. The patients filled in this survey and the Functional Assessment of Cancer Therapy - Bladder Cancer (FACT-BL) survey. To assess reliability, we calculated Cronbach's alpha coefficient and the kappa index. To determine criterion validity, we studied the association between the scores obtained from our survey and those from the FACT-BL survey using the Pearson correlation coefficient. To determine the construct validity (factorial and discriminatory), we performed a factor analysis, comparing it with Student's t-test for the scores obtained according to the tumour characteristics of reduced quality of life (e.g., malignancies located at the trigone of the bladder). Results: Cronbach's alpha reliability coefficient was .83, and the kappa index varied between .7 and 1. For the association study between the new survey and the FACT-BL survey, we measured an r = .82 for the overall score and between r = .68 (disease) and r = .97 (sex life) in the various measures. In the factor analysis, we measured a Kaiser-Meyer-Olkin index of .77 and performed the Barlett test (P < .001). The comparison between the scores, in the presence or absence of certain tumour characteristics, has shown a reduced quality of life when those characteristics are present, which was statistically significant (P < .05) in the majority of cases. Conclusion: Our survey to measure the quality of life of patients with nonmuscle-invasive bladder cancer is reliable and valid
Subject(s)
Humans , Aged, 80 and over , Urinary Bladder Neoplasms/diagnosis , Quality of Life , Self Concept , Neoplasm Invasiveness , Reproducibility of ResultsABSTRACT
OBJECTIVE: To determine the reliability and validity of a quality-of-life survey for patients with nonmuscle-invasive bladder cancer. MATERIAL AND METHODS: A total of 180 patients were included in the study. We developed a survey with 21 questions grouped into 5 areas. The patients filled in this survey and the Functional Assessment of Cancer Therapy - Bladder Cancer (FACT-BL) survey. To assess reliability, we calculated Cronbach's alpha coefficient and the kappa index. To determine criterion validity, we studied the association between the scores obtained from our survey and those from the FACT-BL survey using the Pearson correlation coefficient. To determine the construct validity (factorial and discriminatory), we performed a factor analysis, comparing it with Student's t-test for the scores obtained according to the tumour characteristics of reduced quality of life (e.g., malignancies located at the trigone of the bladder). RESULTS: Cronbach's alpha reliability coefficient was .83, and the kappa index varied between .7 and 1. For the association study between the new survey and the FACT-BL survey, we measured an r=.82 for the overall score and between r=.68 (disease) and r=.97 (sex life) in the various measures. In the factor analysis, we measured a Kaiser-Meyer-Olkin index of .77 and performed the Barlett test (P<.001). The comparison between the scores, in the presence or absence of certain tumour characteristics, has shown a reduced quality of life when those characteristics are present, which was statistically significant (P<.05) in the majority of cases. CONCLUSION: Our survey to measure the quality of life of patients with nonmuscle-invasive bladder cancer is reliable and valid.
Subject(s)
Quality of Life , Self Report , Urinary Bladder Neoplasms , Humans , Neoplasm Invasiveness , Reproducibility of Results , Urinary Bladder Neoplasms/diagnosisABSTRACT
OBJECTIVE: To describe a case of rupture of the deep dorsal vein of the penis during sexual intercourse. METHODS: A 21-year-old patient consulted at the emergency services for acute penis after vigorous sexual intercourse, with clinical features suggestive of rupture of the corpora cavernosa. RESULTS: Surgery demonstrated complete rupture of the deep dorsal vein of the penis, which was repaired. Examination showed no injury to the corpora cavernosa. CONCLUSIONS: Early surgical management is advocated in acute penis, since it will permit us to make the correct diagnosis and treat the underlying cause to avoid future sequelae. Rupture of the deep dorsal vein of the penis is another condition that should be considered in the differential diagnosis of acute penis. Its clinical features are similar to those of cavernosal rupture. Ultrasound and cavernosography are not diagnostic.
Subject(s)
Hematoma/etiology , Penile Diseases/etiology , Penis/blood supply , Penis/injuries , Adult , Coitus , Humans , Male , Rupture , Veins/injuriesABSTRACT
Presentation of one case of seminoma on cryptorchid testicle which presented with torsion of spermatic cord clinically mimicking an inguinal incarcerated hernia. Despite the infrequency of the picture, the high association rate of neoplastic disease in cryptorchid testis which become twisted and force the adoption of oncological criteria for their treatment is highlighted.
Subject(s)
Cryptorchidism/diagnosis , Seminoma/diagnosis , Spermatic Cord Torsion/diagnosis , Testicular Neoplasms/diagnosis , Cryptorchidism/complications , Cryptorchidism/surgery , Diagnosis, Differential , Emergencies , Hernia, Inguinal/diagnosis , Humans , Male , Middle Aged , Orchiectomy , Seminoma/etiology , Seminoma/surgery , Spermatic Cord Torsion/etiology , Spermatic Cord Torsion/surgery , Testicular Neoplasms/etiology , Testicular Neoplasms/surgeryABSTRACT
Presentation of 9 cases of synergistic genitalia and perineum necrosing fascitis treated in our service over the last 5 years. The contents of the disease and its terminology has been reviewed by the light of the existing literature. In our series, patients mean age was 65 years. Three of our 9 patients had diabetes mellitus, and also 3 had liver disease due to alcohol. The initial septic focus was found in 8 cases, and in 4 it was urological, basically urethra's stricture. The most frequently involved germs were aerobe-anaerobe associations. Mortality was 11%.
Subject(s)
Fasciitis , Genital Diseases, Male , Perineum/pathology , Adult , Aged , Aged, 80 and over , Fasciitis/diagnosis , Fasciitis/microbiology , Fasciitis/pathology , Fasciitis/therapy , Genital Diseases, Male/diagnosis , Genital Diseases, Male/microbiology , Genital Diseases, Male/pathology , Genital Diseases, Male/therapy , Humans , Male , Middle Aged , NecrosisABSTRACT
We report on 10 cases of bladder wall calcification after mitomycin C instillation. The cystoscopic and microscopic features of these lesions are described. In our view, these lesions can be ascribed to the use of mitomycin C instillation therapy immediately after TUR. Because they are asymptomatic and occasionally present features of tumor recurrence, biopsy is advocated to determine the true nature of these lesions.
Subject(s)
Calcinosis/chemically induced , Carcinoma, Transitional Cell/drug therapy , Mitomycin/adverse effects , Urinary Bladder Diseases/chemically induced , Urinary Bladder Neoplasms/drug therapy , Administration, Intravesical , Calcinosis/diagnosis , Carcinoma, Transitional Cell/surgery , Chemotherapy, Adjuvant , Combined Modality Therapy , Diagnosis, Differential , Humans , Mitomycin/administration & dosage , Mitomycin/therapeutic use , Neoplasm Recurrence, Local/diagnosis , Neoplasm Recurrence, Local/prevention & control , Urinary Bladder Diseases/diagnosis , Urinary Bladder Neoplasms/surgeryABSTRACT
During a period spanning 11 years, 392 patients diagnosed as having tumor of the bladder were treated at our department. Of these, 9 were patients under age 40. We compared the anatomopathological features and course of the disease. The foregoing condition was suspected on the basis of the urographic findings. We emphasize the need to perform endoscopic inspection and urinary cytology before discarding the presence of a bladder tumor. The anatomopathologic conditions of anaplasia and infiltration are frequently more favourable in this younger patient group, indicating a better prognosis. However, the natural history of tumors with histopathologically similar features is not influenced by age.
Subject(s)
Carcinoma, Transitional Cell , Urinary Bladder Neoplasms , Adult , Carcinoma, Transitional Cell/epidemiology , Carcinoma, Transitional Cell/pathology , Female , Humans , Male , Neoplasm Recurrence, Local/epidemiology , Retrospective Studies , Urinary Bladder Neoplasms/epidemiology , Urinary Bladder Neoplasms/pathologyABSTRACT
A case of orbital metastasis from Whitmore stage D adenocarcinoma of the prostate is described. Clinically, it presented as rapidly progressing exophthalmos of the right eye with elevation (ptosis) and abduction paralysis. The associated clinical picture of a one-year history of prostatism prompted patient referral to our department. When a patient presents with an orbital tumor and a history of cancer localized to another site, the metastatic origin of the condition should be suspected and metastasis to other sites sought. A negative finding warrants performing orbital biopsy to confirm the diagnosis. Although excision of single metastatic tumors in this site has been described, coexisting metastasis to bone and lymph nodes, the hormone dependence that these present and prostatic cancer contraindicate resection of the orbital metastatic tumor. Following bilateral orchiectomy and hormone therapy with antiandrogens micturitional symptomatology improved, tumor size was reduced, and exophthalmos disappeared. The case described herein is not the first case of this type of metastatic lesion reported in the literature; 28 cases have been reported to date. This uncommon clinical presentation with extraurological manifestations gives us an idea of the broad clinical spectrum the biological behaviour of this tumor type can adopt.
Subject(s)
Adenocarcinoma/secondary , Exophthalmos/etiology , Orbital Neoplasms/secondary , Prostatic Neoplasms/complications , Adenocarcinoma/complications , Adenocarcinoma/therapy , Aged , Antineoplastic Agents/therapeutic use , Cyproterone/analogs & derivatives , Cyproterone/therapeutic use , Cyproterone Acetate , Humans , Male , Orbital Neoplasms/complications , Orchiectomy , Palliative Care , Prostatic Neoplasms/therapyABSTRACT
Sarcomas of the prostate are rare tumors and are predominantly rhabdomyosarcoma in children and leiomyosarcoma in the young adult (less than 50 years). We report on a rare case of prostate sarcoma in a 49-year-old patient whose presenting features were those of rapidly evolving prostatism and dyschezia (rectal constipation). The diagnosis was established histopathologically by cytology and biopsy. Despite the initial chemotherapeutic treatment, the course of the disease was fulminant and the patient died from multiple lymphatic metastases. We discuss its embryonal origin, clinical features, differential diagnosis and underscore the need for sequential combined treatment with chemotherapy, surgery and post-operative radiotherapy.
