Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Osteoporos Int ; 24(8): 2335-43, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23460234

ABSTRACT

UNLABELLED: Vitamin D deficiency is a major public health problem, needing immediate attention. We studied the effect of vitamin D fortification of milk in school children. Our results show that fortification of milk is safe and effective strategy to deal with widespread vitamin D deficiency. INTRODUCTION: Vitamin D deficiency among school children and adolescents is a well-documented major public health problem, needing immediate attention. To assess the effect of vitamin D fortified milk on serum 25 hydroxy vitamin D [S.25(OH)D] levels, we carried out a prospective double-blind randomized control trial in apparently healthy school children, aged 10-14 years. METHODS: Of 776 subjects recruited out of 796 who consented, 713 (boys-300; girls-413) completed the study. Subjects were randomized into three groups. Group A (n = 237) received 200 ml of unfortified milk per day while group B (n = 243) and group C (n = 233) received 200 ml of milk fortified with 600 IU (15 µg) and 1,000 IU (25 µg) of vitamin D per day for 12 weeks. Serum calcium, phosphate, alkaline phosphatase, S.25(OH)D, and urinary calcium/creatinine ratio were estimated at baseline and after supplementation. RESULTS: Hypovitaminosis D [25(OH)D < 20 ng/ml] was observed in 92.3 % subjects with mean S.25(OH)D level of 11.69 ± 5.36 ng/ml. There was no significant difference in S.25(OH)D levels among the three groups at baseline. The mean percentage change in S.25(OH)D level in groups B (137.97 %) and C (177.29 %.) were significantly greater than group A (-5.25 %). The percentage of subjects having S.25(OH)D levels >20 ng/ml following supplementation were 5.9 % in group A, 69.95 % in group B, and 81.11 % in group C in comparison to 6.32 %, 4.9 % and 12 %, respectively, at baseline. CONCLUSION: Fortification of milk with vitamin D is an effective and safe strategy in improving S.25(OH)D levels in children aged 10-14 years.


Subject(s)
Cholecalciferol/therapeutic use , Food, Fortified , Milk/chemistry , Vitamin D Deficiency/diet therapy , Adolescent , Animals , Child , Cholecalciferol/administration & dosage , Double-Blind Method , Female , Humans , India/epidemiology , Male , Prospective Studies , Treatment Outcome , Vitamin D/analogs & derivatives , Vitamin D/blood , Vitamin D Deficiency/blood , Vitamin D Deficiency/epidemiology
2.
Indian Pediatr ; 50(9): 859-66, 2013 Sep.
Article in English | MEDLINE | ID: mdl-23502670

ABSTRACT

CONTEXT: Increased prevalence of obesity in childhood and adolescence, defined by the use of body mass index (BMI), has drawn attention towards direct measurement of body fat. OBJECTIVE: To develop age-and sex-specific reference distribution of body fat in apparently healthy North-Indian children in the age group of 7-17 years and to assess agreement between obesity (defined by BMI) and excess body fat. DESIGN: Study subjects for this cross sectional study included 1640 apparently healthy school children (825 boys; 815 girls) aged 7-17 years. Total body fat was measured by dual energy X-rays absorptiometry (DXA). The excess body fat by DXA was defined by two methods, prevalence matching and with the use of 85th and 95th centile cutoffs. RESULTS: The mean ± SD, 3rd, 10th, 25th, 50th, 75th, 90th and 97th centile values of percentage body fat (PBF) are presented. PBF was highly correlated with BMI in both boys and girls (all boys: r=0.76, P<0.0001; all girls r=0.81, P<0.0001). There was no significant difference noted in PBF between boys and girls at the age of 7-8 years. From 9 years onwards, girls had significantly higher PBF than boys. Moderate degree of agreement was observed between BMI and PBF by DXA by both methods. CONCLUSIONS: Smoothened reference distribution of PBF for North-Indian children and adolescents in Delhi are provided. Indian children accumulate more body fat during peri-pubertal years in comparison with US children.


Subject(s)
Adipose Tissue/physiology , Body Composition/physiology , Body Mass Index , Students/statistics & numerical data , Adolescent , Child , Cross-Sectional Studies , Female , Humans , India/epidemiology , Male , Obesity/epidemiology , Reference Values
3.
Appl Opt ; 39(28): 5214-20, 2000 Oct 01.
Article in English | MEDLINE | ID: mdl-18354518

ABSTRACT

The surface-plasmon resonance (SPR) technique is used to study the growth rate and the nature of Ag(2)S films formed on a silver (Ag) film exposed to an atmosphere containing 50% H(2)S for different times. The thickness of the Ag(2)S layer formed, estimated from shifts in the experimental SPR curves, showed a saturation tendency after an initial linear increase. Theoretical analysis of the curves when Ag and Ag(2)S are treated as two uniform layers and Ag-Ag(2)S as a composite layer showed that radiation damping is mainly responsible for the increase of half-width and dip reflectance, indicating that the Ag(2)S film formed is rough and discontinuous.

SELECTION OF CITATIONS
SEARCH DETAIL
...