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Am J Emerg Med ; 30(1): 265.e3-5, 2012 Jan.
Article in English | MEDLINE | ID: mdl-21295430

ABSTRACT

Inhalant abuse is the intentional inhalation of chemical vapors or volatile substance to achieve a euphoric effect. Although no statistical data are reported yet, inhalant abuse is potentially life-threatening and has resulted in a wide range of toxic effects such as central nervous system depression, seizures, aspiration, cardiac arrhythmia, asphyxiation, hypoxia, metabolic acidosis, and sudden death among others. We are reporting a 25-year-old white man who was brought to the emergency department after inhaling aerosolized computer-cleaning spray composed of difluoroethane. He was found to have marked upper and lower lip facial swelling consistent with angioedema. The patient also had a prolonged QT interval, mild inspiratory stridor, but no urticaria. In this case, we believe the difluoroethane-related angioedema represents either idiopathic or bradykinin-induced angioedema.


Subject(s)
Angioedema/chemically induced , Detergents/adverse effects , Hydrocarbons, Fluorinated/adverse effects , Inhalant Abuse/complications , Adult , Angioedema/physiopathology , Electrocardiography , Heart/drug effects , Heart/physiopathology , Humans , Male
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