1.
Pediatr Dermatol
; 18(5): 415-6, 2001.
Article
in English
| MEDLINE
| ID: mdl-11737688
ABSTRACT
Waxy keratoses of childhood is a rare genodermatosis previously noted in both familial and isolated presentations. Three previous cases have been described in which the lesions appeared over the trunk and extremities. We report a case in which the waxy keratoses of childhood lesions appeared in a segmental distribution along a single lower extremity, differing from the more extensive patterns reported previously. We suggest a possible postzygotic mutation hypothesis for this unique segmental distribution, addressing both the possibility of a genomic mosaicism and loss of heterozygosity.
Subject(s)
Keratosis/genetics , Child , Diagnosis, Differential , Female , Humans , Keratosis/diagnosis , Keratosis/pathology
2.
Postgrad Med
; 108(6): 147-9, 2000 Nov.
Article
in English
| MEDLINE
| ID: mdl-11098265