[Studies on the chemical constituents from Daphne tangutica].

OBJECTIVE: To research the chemical constituents from Daphne tangutica. METHODS: Column chromatography with silica gel, ODS-C18, Sephadex LH-20 and re-crystallization were employed to isolate and purify the constituents. According to physical and chemical properties and spectral data to identify the structure of compounds. RESULTS: Eight compounds were isolated and identified as palmitic acid (1), laurostearic acid(2), beta-sitosterol(3), 7-methoxy-8-hydroxycumarin(4), daphnetin(5), genkwanin(6), hydroxygenkwanin(7), p-hydroxybenzoic acid(8). CONCLUSION: Compounds 1,2,7 and 8 are isolated from Daphne tangutica for the first time.