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Relationship between phenotypic and genotypic florfenicol resistance in Escherichia coli.
Singer, Randall S; Patterson, Sheila K; Meier, Anne E; Gibson, Jessica K; Lee, Hannah L; Maddox, Carol W.
Antimicrob Agents Chemother ; 48(10): 4047-9, 2004 Oct.
Article in English | MEDLINE | ID: mdl-15388477

ABSTRACT

This study evaluated the relationship between florfenicol resistance and flo genotypes in 1,987 Escherichia coli isolates from cattle. The flo gene was detected in 164 isolates, all of which expressed resistance to florfenicol at MICs of >/=256 microg/ml. The florfenicol MICs for all isolates that lacked flo were

Subject(s)
Anti-Bacterial Agents/pharmacology , Escherichia coli/drug effects , Escherichia coli/genetics , Thiamphenicol/analogs & derivatives , Thiamphenicol/pharmacology , Animals , Cattle , Cattle Diseases/microbiology , Chloramphenicol Resistance/genetics , Conjugation, Genetic , DNA Primers , Escherichia coli Infections/microbiology , Escherichia coli Infections/veterinary , Feces/microbiology , Genotype , Microbial Sensitivity Tests , Phenotype , Plasmids/genetics , Reverse Transcriptase Polymerase Chain Reaction
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