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Pathologie (Heidelb) ; 45(3): 218-222, 2024 May.
Article in German | MEDLINE | ID: mdl-38472383

ABSTRACT

A radiologically diagnosed tumor in a 29-year-old woman with a fever of around 39 °C was operated on under the suspicion of cholecystitis or a liver abscess. A solid tumor was found in the adrenal gland and resected. The frozen section findings did not reveal a clear diagnosis of entity and assignment. Histologically, the tumor was found to consist of densely clustered large histiocyte-like cells with expression of vimentin, CD68, and CD163 as well as negativity for keratin, langerin, and SMA. We diagnosed xanthogranulomatous adrenalitis and discussed the differential diagnoses (Langerhans cell histiocytosis, Rosai-Dorfman disease, malakoplakia, Erdheim-Chester disease).


Subject(s)
Adrenal Gland Neoplasms , Xanthomatosis , Humans , Adult , Female , Diagnosis, Differential , Adrenal Gland Neoplasms/diagnosis , Adrenal Gland Neoplasms/pathology , Adrenal Gland Neoplasms/surgery , Xanthomatosis/diagnosis , Xanthomatosis/pathology , Xanthomatosis/surgery , Granuloma/diagnosis , Granuloma/pathology , Granuloma/surgery , Adrenal Gland Diseases/diagnosis , Adrenal Gland Diseases/pathology , Erdheim-Chester Disease/diagnosis , Erdheim-Chester Disease/pathology , Histiocytosis, Sinus/diagnosis , Histiocytosis, Sinus/pathology , Histiocytosis, Sinus/surgery
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