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[New ways of correcting metabolic acidosis in experimental periodontitis]. / Novi mozhlivosti korektsii metabolichnogo atsidozu za umov eksperimental'nogo parodontitu.

Biloklits'ka, G F; Pakhomova, V O; Mel'nichuk, D O; Protunkevich, O O; Peti, A O; Sandiga, L G.

Fiziol Zh (1994) ; 46(5): 77-82, 2000.

Article in Ukrainian | MEDLINE | ID: mdl-11269858

ABSTRACT

Established prevention of atrophy of osseous cloth alveolar rats jaws sprouts and correction of metabolic acidosis of mineral concentrate "VITA" attached to modeling parodontit by dint of creation in them of fortune compensated metabolic acidosis. Mineral concentrate realizes normalization redoksfortune, thiol-disulphid system, lowering of relations SH/SS-group, multiplies maintenance oxidized and lowers maintenance restored of nicotinamid copherments, normalize relation HA[symbol: see text]/HA[symbol: see text]H in osseous jaws cloth of experimental rats attached to modeling in them metabolic acidosis and parodontit in distinction from fortune of alkalosis. Mineral complex will normalize in rats maintenance of regulators and orientation of exchange processes in cloths attached to parodontit, whereat indicates lowering of activity key gluconeogenesis processes enzyme fructosodiphosphatasa of liver cloths, mucous gum and alveolar sprouts of jaws.

Subject(s)

Acidosis/drug therapy , Periodontitis/drug therapy , Acidosis/metabolism , Alveolar Bone Loss/prevention & control , Animals , Disulfides/metabolism , Fructose-Bisphosphatase/metabolism , Gluconeogenesis/physiology , Minerals/therapeutic use , NAD/metabolism , Rats , Rats, Wistar , Water/chemistry

[Interrelation of fetal metabolism and late pregnancy in animals]. / Deiaki aspekti vzaiemozv'iazku obminu rechovin u vagitnykh tvarin ta ïkh plodiv

Tupits'ka, O M; Zakharenko, M O; Mel'nichuk, D O; Zasiekin, D A; Smovzh, S A.

Ukr Biokhim Zh (1978) ; 69(2): 35-40, 1997.

Article in Ukrainian | MEDLINE | ID: mdl-9463237

ABSTRACT

Parameters of were determined for acid-alkali state of blood, energy, nitrogen, protein and mineral metabolism in fetuses and animals at the last period of pregnancy. It was established that one can observe the state of compensated acidosis, intensification of glycolytic and inhibition ot aerobic processes in animals with late pregnancy; that is evidenced by changes in the content of glucose, the level and the value of correlation of the components of lactate-, malate- and glutamate dehydrogenase systems, activity of lactate dehydrogenase, alkali phosphatase, alanine- and aspartate aminotransferase as well as electrolyte composition of the organism tissues. Analogous changes in metabolism are observe in the fetus tissues in late antenatal period of development.

Subject(s)

Energy Metabolism , Fetus/metabolism , Pregnancy, Animal/metabolism , Alanine Transaminase/blood , Alkaline Phosphatase/blood , Animals , Aspartate Aminotransferases/blood , Embryonic and Fetal Development , Female , Glutamate Dehydrogenase/blood , Hydrogen-Ion Concentration , L-Lactate Dehydrogenase/blood , Malate Dehydrogenase/blood , Minerals/metabolism , Nitrogen/metabolism , Pregnancy , Pregnancy, Animal/blood , Proteins/metabolism , Rats , Rats, Wistar , Water-Electrolyte Balance

[Dependence of biosynthetic processes in rabbits on carboxylation reactions]. / Zalezhnist' biosyntetychnykh protsessiv vid reaktsii karboksyliuvannia u kroliv.

Gulin, M F; Mel'nichuk, D O; Mal'ko, V A.

Ukr Biokhim Zh ; 44(1): 34-7, 1972.

Article in Ukrainian | MEDLINE | ID: mdl-5052760

Subject(s)

Carboxy-Lyases/antagonists & inhibitors , Liver/metabolism , Muscles/metabolism , Animals , Carbon Dioxide/metabolism , Carbon Isotopes , Lipids/biosynthesis , Liver Glycogen/metabolism , Protein Biosynthesis , Rats

[Carboxylation in the formed elements of blood from rabbits cows and chickens]. / Pro naiavnist' protsesiv karboksyliuvannia u formenykh elementakh krovi kroliv, koriv ta kurei.

Gulii, M F; Mel'nichuk, D O; Mal'ko, V A; Shevchenko, M I.

Ukr Biokhim Zh ; 43(4): 498-502, 1971.

Article in Ukrainian | MEDLINE | ID: mdl-5154545

Subject(s)

Blood Cells/metabolism , Carbon Dioxide/blood , Adenosine Triphosphate/pharmacology , Animals , Cattle , Chickens , Glucose/pharmacology , Ketoglutaric Acids/pharmacology , Pyruvates/pharmacology , Rabbits

[Effect of sodium bicarbonate, Mn++, Mg++ and Zn++ on intensity of renewal of proteins, glycogen and lipids in rabbit liver and muscles]. / Vplyv bikarbonatu matriiu, Mn, Mg I Zn na intensyvnist' onovlennia bilkiv, hlikohenu ta lipidiv u pechintsi ta m'iazakh kroliv.

Gulyi, M F; Mel'nichuk, D O; Klimenko, M D.

Ukr Biokhim Zh ; 40(2): 167-72, 1968.

Article in Ukrainian | MEDLINE | ID: mdl-5696398

Subject(s)

Bicarbonates/pharmacology , Glycogen/metabolism , Lipids/biosynthesis , Liver/metabolism , Manganese/pharmacology , Muscles/metabolism , Protein Biosynthesis , Zinc/pharmacology , Acetates/metabolism , Animals , Carbon Dioxide/metabolism , Carbon Isotopes , Glycogen/biosynthesis , Liver Glycogen/biosynthesis , Liver Glycogen/metabolism , Muscle Proteins/biosynthesis , Rabbits , Sodium , Stimulation, Chemical , Sulfates

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