ABSTRACT
This study included 160 patients (mean age 53.4 +/- 1.32 years) with type 2 diabetes mellitus of whom 99 (61.8%) had adequately compensated metabolic disorders and the remaining ones suffered uncompensated disease. All the patients were allocated to 4 groups differing in terms of dietary therapy (two treatment and two control groups). It was shown that treatment with the high-fiber diet (46-55 g/day) in combination with mineral water markedly accelerated normalization of blood glucose level and lipid metabolism, reduction of body weight and arterial pressure; moreover, it improved general efficiency of therapy.
Subject(s)
Diabetes Mellitus, Type 2/diet therapy , Dietary Fiber/administration & dosage , Mineral Waters/administration & dosage , Blood Glucose/metabolism , Blood Pressure/drug effects , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/pathology , Diabetes Mellitus, Type 2/physiopathology , Female , Humans , Lipid Metabolism/drug effects , Male , Middle Aged , Weight Loss/drug effectsABSTRACT
The word deals with the results obtained in the study of the reactogenicity and immunological activity of concentrated and inactivated tissue-culture tick-borne encephalitis vaccine, manufactured by the Chumakov Institute of Poliomyelitis and Viral Encephalitides, in the immunization of children and adolescents. The vaccine proved to be moderately reactogenic and exhibited pronounced immunological activity. In 91.5% of the immunized children the fourfold increase of the antibody level was observed. On the basis of the data obtained in this study the tick-borne encephalitis vaccine was recommended for use in medical practice for the prophylaxis of tick-borne encephalitis among children and adolescents.
Subject(s)
Encephalitis Viruses, Tick-Borne/immunology , Encephalitis, Tick-Borne/prevention & control , Immunization/methods , Viral Vaccines/immunology , Adolescent , Analysis of Variance , Antibodies, Viral/blood , Austria , Child , Humans , Immunization/statistics & numerical data , Immunization, Secondary/methods , Immunization, Secondary/statistics & numerical data , Russia , Time Factors , Vaccines, Inactivated/adverse effects , Vaccines, Inactivated/immunology , Viral Vaccines/adverse effectsABSTRACT
The authors have performed combined therapy of 300 patients with acute and subacute neurosensory hypoacusis varying in etiology, 45 patients with acute and subacute disorders of the olfactory analyzer caused by previous infections, emotional stress, inhalation of irritants. The treatment included a 10-day course of reflex therapy, antihypoxic and vasoactive drugs. As a result, a positive trend was observed in acoustic, vestibular and olfactory functions in the majority of cases. The scheme is proposed for routine otorhinolaryngological practice.
Subject(s)
Hearing Loss, Sensorineural/therapy , Neural Analyzers , Olfaction Disorders/therapy , Reflexotherapy , Smell , Humans , Olfaction Disorders/etiology , Time FactorsABSTRACT
Factors responsible for barotraumas of the middle and internal ear of divers are discussed. A rapid, uncontrollable change in the intratympanic pressure upon diving may cause tympanum perforation, injury and displacement of auditory ossicles which, in turn, may lead to excitation of vestibular receptors. Barotraumas of the middle ear may also be produced by exostoses of the auditory meatus. The present work describes follow-up data of two divers who were grounded due to external and middle ear problems. One of them was operated on to remove bone exostoses that obturated the auditory meatus. The other diver underwent surgery to close the tympanic "barometric" perforation. After reconstructive surgery both divers resumed their professional activities. Both cases were followed-up for over three years.
Subject(s)
Barotrauma/surgery , Diving/adverse effects , Ear, Inner/surgery , Ear, Middle/surgery , Occupational Diseases/surgery , Adult , Barotrauma/etiology , Barotrauma/rehabilitation , Ear, Inner/injuries , Ear, Middle/injuries , Humans , Male , Occupational Diseases/etiology , Occupational Diseases/rehabilitation , Postoperative Period , Retrospective StudiesABSTRACT
Forty patients with acute neurosensory hypoacusis of vascular genesis were exposed to combined treatment that included hyperbaric oxygenation (HBO) and drug therapy to improve microcirculation, vasodilation and metabolism. In order to control HBO side effects (vasoconstriction), the patients were subdivided into two subgroups of 20 subjects each. Group 1 patients were treated with HBO immediately before drug administration and Group 2 patients were treated with HBO immediately after drug administration. Good effects in Group 2 patients were twice as large. This was achieved by elimination of HBO side effects due to drug administration immediately before hyperbaric exposure.
Subject(s)
Hearing Loss, Sensorineural/therapy , Hyperbaric Oxygenation , Adult , Cerebrovascular Disorders/complications , Female , Hearing Loss, Sensorineural/drug therapy , Hearing Loss, Sensorineural/etiology , Humans , Male , Middle AgedABSTRACT
The frequency and extent of lymphogenic dissemination of cervical carcinoma versus histologic type, growth pattern and degree of local spread of tumor were studied on the basis of clinico-roentgenological data on 131 cases. Regional metastases developed in external and general iliac lymph nodes. Locally disseminated T1b, T2a and T3 tumors made the case for lymphography because it provided data necessary for radiation treatment planning. Roentgenologic follow-up and repeated lymphography were instrumental in evaluating the effectiveness of radiation treatment and detected lymphogenic metastases in 7.3% of cases.
Subject(s)
Uterine Cervical Neoplasms/diagnostic imaging , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/pathology , Adult , Aged , Carcinoma in Situ/diagnostic imaging , Carcinoma in Situ/pathology , Carcinoma, Squamous Cell/diagnostic imaging , Carcinoma, Squamous Cell/pathology , Female , Humans , Lymphatic Metastasis , Lymphography , Middle Aged , Neoplasm Staging , Uterine Cervical Neoplasms/pathologySubject(s)
Brachytherapy/adverse effects , Radiation Injuries/epidemiology , Rectum/radiation effects , Uterine Cervical Neoplasms/complications , Brachytherapy/instrumentation , Female , Humans , Radiation Injuries/therapy , Radioisotope Teletherapy/adverse effects , Time Factors , Uterine Cervical Neoplasms/radiotherapySubject(s)
Contrast Media/metabolism , Lymph Nodes/metabolism , Lymphography , Adult , Female , Humans , Lymphatic Metastasis , Middle Aged , Radiotherapy Dosage , Time Factors , Uterine Cervical Neoplasms/metabolism , Uterine Cervical Neoplasms/therapy , Uterine Neoplasms/metabolism , Uterine Neoplasms/therapyABSTRACT
The state of urinary organs was examined in 126 patients when using for an associated radiotherapy of cervical cancer a high-dose-rate pipe apparatus "Agat-B" together with moving distant gamma-therapy. Early radiation cystitis was noted in 31 (24.6%) patients, which was not the cause of development of late radiation injuries. Late radiation catarrhal cystitis was revealed in 26 (21.7%) patients, ulcerous--in 17 (13.8%), during the first year radiation cystitis being noted in 12 (11.2%) patients, following two years--in 21 (22.6%), following three years--in 11 (14.5%) among the examined patients. Reduced functioning in the upper urinary tract more frequently occurred during the first year after the therapy, as noted in 50 (59.6%) patients. No increase was found in the number of complications on the part of urinary organs while employing this method of associated radiotherapy compared with other technics.