ABSTRACT
In otorhinolaryngology, the relationship between gastroesophageal reflux (GER) and pharyngolaryngeal disorders is well-known. In fact, many patients with GER debut with head and neck symptoms or are first seen by an otolaryngologist. We proposed to identify the ENT symptoms most frequently associated with GER, to differentiate between physiological and pathological GER, and to confirm the effectiveness of antacid treatment. Our study included 20 ambulatory patients who presented pharygolaryngeal symptoms and clinical manifestations of GER (heartburn and regurgitation). The patients underwent a complete ENT examination and were referred to a gastroenterologist for esophagoscopy, manometry, and 24-hour pH monitoring. All patients received antireflux therapy for one month (ranitidine 150 mg given twice daily). We conclude that GER produces a variety of manifestations, but the most frequent pharyngolaryngeal symptoms and physical findings were globus pharyngeus and erythema of the arytenoids, respectively. Pathological GER was found in only one third of our patients and 90% responded well to treatment.
Subject(s)
Anti-Ulcer Agents/therapeutic use , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/drug therapy , Laryngeal Diseases/etiology , Pharyngeal Diseases/etiology , Ranitidine/therapeutic use , Humans , Laryngeal Diseases/diagnosis , Laryngoscopy/methods , Manometry/methods , Pharyngeal Diseases/diagnosisABSTRACT
The rate of occurrence of neoplasma arising from the parapharyngeal space is scarce, about 0.5 percent of neck and face tumors. In the paper is reported our 10-year experience on its clinical diagnosis and therapeutical management as well. We have found 13 percent (3/23) malignancies and 87 percent (20/30) benign growth. 35 percent were paragangliomas and 22 percent represent salivary tumors. Diagnostic procedures, ways of approach and surgical complications are considered.
Subject(s)
Pharyngeal Neoplasms/pathology , Pharynx/pathology , Salivary Gland Neoplasms/pathology , Salivary Glands/pathology , Adolescent , Adult , Female , Humans , Male , Middle Aged , Pharyngeal Neoplasms/diagnosis , Pharyngeal Neoplasms/surgery , Pharynx/surgery , Postoperative Complications , Salivary Gland Neoplasms/diagnosis , Salivary Gland Neoplasms/surgery , Salivary Glands/surgery , Tomography, X-Ray ComputedABSTRACT
We analyzed the DNA nuclear content and cellular cycle distribution of the healthy laryngeal tissues without any laryngeal disease (healthy) and that of from patients afflicted with laryngeal epidermoid carcinoma (healthy/Ca). We have carried out studies on fresh samples, unfixed samples, and analysing them immediately after their extraction in the flow cytometer, using human peripheral blood lymphocytes as control of the ploidy in each case. In the study effected, we did not find any differences in the DNA content of the healthy laryngeal tissues and those macroscopically healthy from patients with epidermoid carcinoma of the larynx. However, the laryngeal tissues show a significantly higher DNA content than the human peripheral blood lymphocytes used as check.
Subject(s)
DNA/chemistry , Flow Cytometry , Larynx/physiology , Carcinoma, Squamous Cell/chemistry , Carcinoma, Squamous Cell/pathology , Culture Techniques , Female , Humans , Larynx/chemistry , Larynx/pathology , Lymphocytes/chemistry , MaleABSTRACT
We present a case of intracranial Tuberculoma of the cerebellopontine angle and discuss the problems to set up the preoperative etiological diagnosis. Finally we make a review of the literature of the subject.
Subject(s)
Brain Diseases/diagnosis , Cerebellopontine Angle/diagnostic imaging , Tuberculoma/diagnosis , Brain Diseases/diagnostic imaging , Humans , Male , Middle Aged , Radiography , Tuberculoma/diagnostic imagingABSTRACT
We carried out a clinical study on the manifestations of various connective tissue pathologies of the head and neck. The need to suspect the presence of these pathological entities from non-specific ENT symptoms and performing early diagnoses of cochleovestibular diseases on the basis of a clinical and examination protocol is emphasized.
Subject(s)
Collagen Diseases/complications , Otorhinolaryngologic Diseases/etiology , Adult , Aged , Arthritis, Rheumatoid/complications , Female , Humans , Lupus Erythematosus, Systemic/complications , Male , Middle Aged , Mixed Connective Tissue Disease/complications , Polychondritis, Relapsing/complications , Scleroderma, Systemic , Sjogren's Syndrome/complicationsABSTRACT
The AA. present a review of the expansive processes of the cerebellopontine angle (CPA) diagnosed at their Department, during the six last years. Emphasis is made upon the clinic findings gained through neuro-otological explorations and imaging, both helpful for preoperative diagnosis of the nature of the tumor.
Subject(s)
Cerebellar Neoplasms/diagnosis , Cerebellopontine Angle , Meningeal Neoplasms/diagnosis , Meningioma/diagnosis , Neuroma, Acoustic/diagnosis , Abducens Nerve , Adult , Aged , Cerebellar Diseases/diagnosis , Cholesteatoma/diagnosis , Cranial Nerve Neoplasms/diagnosis , Diagnosis, Differential , Facial Nerve , Female , Humans , Male , Middle Aged , Neurilemmoma/diagnosis , Tomography, X-Ray ComputedABSTRACT
We present a case of rhinocerebral mucormycosis in a 47 years old woman without diabetic or immunodepression past. The diagnosis was confirmed through a histological study of the material obtained after surgery. The treatment with amphotericin B and radical surgery showed ineffective. The patient died two weeks after entrance. We make an evaluation of the etiopathological, clinical and therapeutic aspects and also a revision of the relevant literature.
