ABSTRACT
In a series of 230 patients admitted to hospital with a stroke, the frequency and significance of epileptic seizures at onset was assessed. Thirteen (5.7%) suffered single or multiple witnessed seizures at the onset of their stroke. Seizures were evenly distributed among all pathological stroke sub-types but were restricted to lesions in the carotid artery territory. They indicated a poorer prognosis over the first 2 days. Six of the 13 presenting with stroke and seizures had prior seizures and, if they survived, continued to have fits. The five patients surviving with stroke and a first seizure were all fit-free after 30 months follow-up.
Subject(s)
Cerebrovascular Disorders/complications , Epilepsy/etiology , Adult , Aged , Cerebral Hemorrhage/complications , Cerebral Infarction/complications , Female , Humans , Ischemic Attack, Transient/complications , Male , Middle Aged , PrognosisABSTRACT
We report a family in which the father and all three children had symptomless chronic renal failure and, in the case of the children, normocytic, normochromic anaemia. None had hypertension, proteinuria, or abnormality of urinary deposit. Renal biopsy specimens showed microcysts confined to the renal cortex; some cysts contained vestigial glomerular tufts. This family appears to represent the first known example of hereditary cortical microcystic disease. The distribution of the disease suggests dominant inheritance without sex linkage.
Subject(s)
Kidney Cortex , Polycystic Kidney Diseases/genetics , Adolescent , Adult , Anemia/genetics , Anemia/metabolism , Child , Female , Genes, Dominant , Humans , Kidney Cortex/pathology , Kidney Failure, Chronic/genetics , Kidney Failure, Chronic/metabolism , Kidney Failure, Chronic/pathology , Male , Polycystic Kidney Diseases/metabolism , Polycystic Kidney Diseases/pathology , SyndromeABSTRACT
A 57-year-old man with splenic abscess, demonstrated by isotope scanning, ultrasonography and computerized axial tomography (CAT scan) during the course of a septicaemic illness resulting from culture-positive bacterial endocarditis, was successfully treated with antibiotics alone, resolution of the abscess being confirmed by 2 further scans. This is the second case report of successful conservative treatment of splenic abscess.
