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Fertil Steril ; 56(4): 778-80, 1991 Oct.
Article in English | MEDLINE | ID: mdl-1915958

ABSTRACT

Recurrence of heavy vaginal bleeding and massive necrosis of a uterine leiomyosarcoma are reported in a 41-year-old female who was being treated with GnRH-a for a presumed uterine fibroid. The pathogenic mechanisms of such an event are reviewed and discussed in light of the available literature on the subject of GnRH-a and the treatment of uterine smooth muscle neoplasms.


Subject(s)
Leiomyosarcoma/pathology , Leuprolide/therapeutic use , Uterine Neoplasms/pathology , Adult , Female , Humans , Leiomyosarcoma/complications , Leuprolide/adverse effects , Necrosis , Uterine Hemorrhage/etiology , Uterine Neoplasms/complications , Uterus/pathology
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