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1.
Genome Announc ; 5(20)2017 May 18.
Article in English | MEDLINE | ID: mdl-28522705

ABSTRACT

We present here the draft genome sequences of two colistin-resistant mcr-1-carrying Escherichia coli strains belonging to sequence type 74 (ST74) and ST1850, isolated from commercial chicken meat in Brazil. Assembly of this draft genome resulted in 5,022,083 and 4,950,681 bp, respectively, revealing the presence of the IncX4 plasmid-mediated mcr-1 gene responsible for resistance to colistin.

2.
Article in English | MEDLINE | ID: mdl-28193665

ABSTRACT

The detection and rapid spread of colistin-resistant Enterobacteriaceae carrying the mcr-1 gene has created an urgent need to strengthen surveillance. In this study, eight clonally unrelated colistin-resistant Escherichia coli isolates carrying mcr-1 and blaCTX-M or blaCMY-2 genes were isolated from commercial chicken meat in Brazil. Most E. coli strains carried IncX4 plasmids, previously identified in human and animal isolates. These results highlight a new reservoir of mcr-1-harboring E. coli strains in South America.


Subject(s)
Anti-Bacterial Agents/pharmacology , Chickens/microbiology , Colistin/pharmacology , Drug Resistance, Bacterial/genetics , Escherichia coli Proteins/genetics , Escherichia coli/genetics , Meat Products/microbiology , Animals , Brazil , Escherichia coli/drug effects , Escherichia coli/isolation & purification , Escherichia coli Infections/drug therapy , Foodborne Diseases/drug therapy , Foodborne Diseases/microbiology , Foodborne Diseases/prevention & control , Humans , Plasmids/genetics , beta-Lactamases/genetics
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