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1.
Rev Esp Enferm Dig ; 95(10): 730-2, 727-9, 2003 Oct.
Article in English, Spanish | MEDLINE | ID: mdl-14588067

ABSTRACT

UNLABELLED: Percutaneous ethanol injection is a useful option in the treatment of hepatocellular carcinoma which are not amenable to resection or transplantation. We describe a case of cholecystitis and tumour infiltration of the gallbladder after percutaneous ethanol injection, a complication not previously described in literature. The patient was a 70-year-old woman with a history of asymptomatic HCV+ hepatopathy and a 6 cm hepatocellular carcinoma nodule in segment V which had been treated two months before by percutaneous ethanol injection in another center. She attended our center due to febrile syndrome. Imaging studies suggested cholecystitis with an abscess on the wall of the gallbladder, purulent material obtained by means of a CT-guided puncture. Surgery revealed purulent and neoplasic material inside the gallbladder, with tumor invasion of the posterior wall; a partial cholecystectomy was therefore performed and a drainage inserted. The patient showed no post-operative complications and was discharged after seven days. CONCLUSION: we believe that the percutaneous ethanol injection of hepatocellular carcinomas located close to the gallbladder may occasionally lead to complications in the form of cholecystitis with neoplasic infiltration of the gallbladder. A case of cholecystitis secondary to radiofrequency treatment of a similarly-located tumor has previously been described and, therefore, the use of percutaneous local destructive treatments for tumors close to the gallbladder would seem unadvisable.


Subject(s)
Carcinoma, Hepatocellular/drug therapy , Cholecystitis, Acute/chemically induced , Ethanol/adverse effects , Liver Neoplasms/drug therapy , Administration, Cutaneous , Aged , Carcinoma, Hepatocellular/diagnostic imaging , Carcinoma, Hepatocellular/pathology , Cholecystectomy , Cholecystitis, Acute/diagnostic imaging , Cholecystitis, Acute/therapy , Female , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/pathology , Neoplasm Invasiveness , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography
2.
Rev. esp. enferm. dig ; 95(10): 727-729, oct. 2003. ilus
Article in Spanish | IBECS | ID: ibc-137000

ABSTRACT

La alcoholización percutánea es una opción útil en el tratamiento de los hepatocarcinomas no candidatos a resección o trasplante. Describimos un caso de colecistitis e infiltración tumoral intravesicular tras alcoholización, complicación no descrita hasta el momento. Paciente de 70 años con el antecedente de hepatopatía VHC+ bien compensada y un nódulo de hepatocarcinoma de 6 cm en segmento V que, dos meses antes, recibió tratamiento mediante alcoholización percutánea en otro centro. Acudió a nuestro centro por síndrome febril. Las pruebas de imagen sugirieron colecistitis con abscesificación yuxtavesicular, obteniéndose material purulento mediante la punción guiada por TAC. Se decidió intervención quirúrgica, hallándose un contenido intravesicular purulento y neoplásico, con invasión tumoral de su pared posterior, por lo que se realizó una colecistectomía parcial dejando un drenaje. La paciente no presentó incidencias postoperatorias y fue dada de alta a los 7 días. Conclusión: consideramos que la alcoholización de los hepatocarcinomas localizados cerca de la vesícula biliar puede producir como complicación excepcional una colecistitis con infiltración neoplásica intravesicular. Se ha descrito un caso de colecistitis secundaria al tratamiento mediante radiofrecuencia de un tumor de similar localización, por lo que consideramos desaconsejable la realización de tratamientos destructivos locales por vía percutánea en tumores ubicados cerca de la vesícula biliar (AU)


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Subject(s)
Aged , Female , Humans , Carcinoma, Hepatocellular/drug therapy , Cholecystitis, Acute/chemically induced , Cholecystitis, Acute , Cholecystitis, Acute/therapy , Ethanol/adverse effects , Liver Neoplasms/drug therapy , Administration, Cutaneous , Carcinoma, Hepatocellular/pathology , Carcinoma, Hepatocellular , Cholecystectomy , Liver Neoplasms/pathology , Liver Neoplasms , Neoplasm Invasiveness , Tomography, X-Ray Computed , Treatment Outcome
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