1.
BMJ Case Rep
; 14(3)2021 Mar 17.
Article
in English
| MEDLINE
| ID: mdl-33731397
ABSTRACT
Disulfiram has been widely used for over six decades in the treatment of alcohol dependence, as an aversive therapeutic agent. Despite having very few side effects when taken without concurrent alcohol consumption, some of these may underlie serious clinical complications. Epileptic seizure induction is a rare adverse effect of disulfiram and its aetiological mechanism is unknown. We present a hospitalised 47-year-old male patient with two episodes of generalised tonic-clonic seizures during treatment with disulfiram while abstinent from alcohol.
Subject(s)
Epilepsies, Partial , Epilepsy, Generalized , Epilepsy, Tonic-Clonic , Anticonvulsants/adverse effects , Carbamazepine/therapeutic use , Disulfiram/adverse effects , Epilepsy, Generalized/drug therapy , Humans , Male , Middle Aged , Seizures/chemically induced , Seizures/drug therapy
2.
Asian J Psychiatr
; 54: 102383, 2020 Dec.
Article
in English
| MEDLINE
| ID: mdl-33271692