The influence of a diet based on flaxseed, an omega-3 source, during different developmental periods, on the blood pressure of rats submitted to stress.

OBJECTIVE: This study aimed to investigate a flaxseed diet during different developmental periods, and its effect on the blood pressure of rats submitted to stress. METHODS: Fifty-six male rats (F1), born from 14 rats (F0), were divided into seven groups (n = 8): flaxseed group (FG); flaxseed group gestation and lactation (FG-GL); flaxseed group weaning (FG-W); flaxseed group weaning and stress (FG-WS); flaxseed group stress (FG-S); flaxseed group gestation lactation and weaning (FG-GLW), and control Group (CG). Stress protocol was undertaken for 1 month. Blood pressure was analysed before and after the stress protocol. The left adrenal glands and serum corticosterone levels were analysed. RESULTS: Systolic blood pressure before stress was lower in all groups with flaxseed diet compared with the CG (p = .00001). After stress, CG showed higher blood pressure compared with FG, FG-GL, and FG-GLW (p = .004). The levels of corticosterone were lower in the FG between all groups (p < .000001) and the CG showed higher compared with FG-W, FG-WS, FG-GL, and FG-GLW (p < .0001). The adrenal gland did not show differences. CONCLUSIONS: Results suggest a possible factor from a flaxseed diet against the effects of stress on a blood pressure in all periods of life but especially in the gestation and lactation periods.

Estudo de recuperação de danos neurológicos em ratos submetidos à hipoxia com o uso da semente de linhaça somado ao enriquecimento ambiental / Recovery study of neurological damage in rats submitted to hypoxia with the use of flaxseed added to environmental enrichment

A semente de linhaça possui uma alta concentração de ômega 3 e seu consumo associado a um ambiente enriquecido pode promover resultados distintos sobre uma lesão hipóxica. O objetivo deste trabalho foi avaliar o efeito neuroprotetor de uma dieta a base a base de ômega 3 com o enriquecimento ambiental em uma lesão cerebral de ratos neonatos...Apenas a linhaça pareceu ser papel crucial no aumento do peso cerebral relativo, sugerindo maior agregação desses ácidos graxos no sistema nervoso. Os resultados dos testes sugeriram que uma dieta a base de linhaça pode aumentar o fator neuroprotetor apresentado pelo enriquecimento ambiental.