1.
Org Biomol Chem
; 20(8): 1642-1646, 2022 02 23.
Article
in English
| MEDLINE
| ID: mdl-35108719
ABSTRACT
Catalytic construction of oxindoles bearing all-carbon-quaternary centers attracts wide attention from the synthetic chemistry community. Herein, we report a palladium-catalyzed sequential Heck coupling/C-C bond activation of aryl halide-tethered alkenes with benzocyclobutenols affording a series of oxindole-derived compounds in good to excellent yields, as well as the preliminary enantioselectivity results.