Determinants of speech and language delay among children aged 12 months to 12 years at Yekatit 12 Hospital, Addis Ababa, Ethiopia: a case-control study.

BACKGROUND: Speech and language delay among children can result in social interaction problems, attention difficulties, decreased writing and reading abilities, and poor cognitive and behavioral development. Despite the mounting prevalence of speech and language delays in Ethiopia, there is a lack of literature addressing the factors contributing to this delay. Consequently, this study aims to identify determinants of speech and language delay among children aged 12 months to 12 years at Yekatit 12 Hospital in Addis Ababa, Ethiopia. METHODS: We conducted an institutional-based at Yekatit 12 Hospital, unmatched case-control study with 50 cases and 100 controls aged 12 months to 12 years. Interviewer-administered questionnaires were used to collect data from the parents or caregivers of the participating children. Epi Info v7 was used for sample calculation, and SPSS v26 was used for analysis. The chi-square test was performed to determine the relationship between speech and language delay and determining factors, which was then followed by logistic regression. The significant determining factors were identified based on the adjusted odds ratio (AOR), with a 95% CI and p-value (< 0.05). RESULTS: Case group constituted 23 males and 27 females, totaling 50 children. Upon completing the multivariate analysis, birth asphyxia [AOR = 4.58, 95CI (1.23-16.99)], bottle-feeding [AOR = 4.54, 95CI (1.29-16.04)], mother-child separation [AOR = 2.6, 95CI (1.05-6.43)], multilingual family [AOR = 2.31, 95CI (1.03-5.18)], and screen time greater than two hours [AOR = 3.06, 95CI (1.29-7.28)] were found to be statistically significant determinants of speech and language delay. CONCLUSIONS: Our study found that birth asphyxia, bottle-feeding, mother-child separation, being from a multilingual family, and excessive screen time contribute significantly to speech and language delay. As a result, it is important to develop interventions that target these modifiable factors, while also ensuring that early diagnosis and treatment options are readily accessible.

Prevalence of compassion fatigue, burnout, compassion satisfaction, and associated factors among nurses working in cancer treatment centers in Ethiopia, 2020.

BACKGROUND: Overuse of compassion for those under the care may threaten their professional life. In Ethiopia, there is limited study on the consequences of compassionate care. Therefore, the study assessed the effects of compassionate care among nurses. OBJECTIVE: To quantify the prevalence of compassion satisfaction, burnout, compassion fatigue, and associated factors among Nurses. METHODS: Institution-based quantitative cross-sectional design was conducted in five randomly selected public hospitals in Ethiopia, from May to April 2020. All the nurses who were working in the cancer treatment centers of the five hospitals were included in the study. Data were collected using a standard self-administer structured question using the Professional Quality of Life Scale (PROQOL) instrument version 5. The data were analyzed by using the SPSS 21version. Descriptively: frequency, mean, standard deviation, and inferential statistics: t-Test and one-way analysis of variance (ANOVA), and multiple linear regression analysis were computed. RESULT: The majority of respondents 154 (67.0%) were female. The age of the participants ranges from 20 to 65 (32.06 + 7.45) years. The mean (SD) scores for the dimensions of compassion satisfaction, burnout, and compassion fatigue were 34.41 (6.74), 27.70 (4.24), and 35.83 (7.78) respectively. Neuroticism personality trait had positivity related to compassion fatigue (P = 0.001). Nurses who received low monthly income had significantly lower scores for compassion fatigue (P = 0.002). We found friend support, openness, sex, and agreeableness explained 32.7% (p < 0.024) of the variances in compassion satisfaction. CONCLUSION: In general the study found high compassion fatigue and low compassion satisfaction. Further, having low income and neuroticism personality were related to compassion fatigue, while agreeableness, consciousness, and openness personality were related to compassion satisfaction. Therefore, attention should be given to nurses working in cancer centers to ensure positive energy.

The pattern of orthopedic fractures and visceral injury in road traffic crash victims, Addis Ababa, Ethiopia.

BACKGROUND: Road Traffic crash injury is one of the main public health problems resulting in premature death and disability particularly in low-income countries. However, there is limited evidence on the crash fractures in Ethiopia. OBJECTIVE: The study was conducted to assess the magnitude of road traffic crash fractures and visceral injuries. METHODS: A hospital-based cross-sectional study was conducted on 420 fracture patients. Participants were randomly selected from Addis Ababa City hospitals. The study was carried out between November 2019 and February 2020. Data were collected using a questionnaire and record of medical findings. Multilevel logistic regression analysis was carried out. Ethical clearance was obtained from the Addis Ababa University, College of Health Sciences Institutional Review Board. Confidentiality of participants' information was maintained. RESULTS: The study found out that the majority 265 (63. 1%) of fracture cases were younger in the age group of 18 to 34 years. Males were more affected-311(74.0%). The mortality rate was 59(14.1%), of those 50(85.0%) participants were males. The major road traffic victims were pedestrians-220(52.4%), mainly affected by simple fracture type -105(53.3%) and compound fracture type-92(46. 7%). Drivers mainly suffered from compound fracture type -23 (59.0%). One hundred eighty-two (43.3%) of fracture patients had a visceral injury. Homeless persons who sit or sleep on the roadside had a higher risk of thoracic visceral injury compared to traveler pedestrians (AOR = 4.600(95%CI: 1.215-17.417)); P = 0.025. CONCLUSION: Visceral injury, simple and compound fractures were the common orthopedic injury types reported among crash victims. Males, pedestrians, and young age groups were largely affected by orthopedic fracture cases. Homeless persons who sited or slept on the roadside were significant factors for visceral injury. Therefore, preventing a harmful crash and growing fracture care should be considered to reduce the burden of crash fracture.

Survival and Predictors of Mortality Among Adult HIV/AIDS Patients Initiating Highly Active Antiretroviral Therapy in Debre-Berhan Referral Hospital, Amhara, Ethiopia: A Retrospective Study.

BACKGROUND: Acquired immune deficiency syndrome is one of the most destructive epidemics the world has ever witnessed. An estimated 36.9 million people were living with HIV in 2017. HIV/AIDS is the major contributing factor for morbidity and mortality in low- and middle-income countries. Although different studies on survival and predictors of mortality among HIV/AIDS patients after initiation of antiretroviral therapy were conducted, there are inconsistencies in the findings of those studies. Furthermore, to the authors' knowledge, there was a dearth of studies conducted in this study area. PURPOSE: The purpose of this study was to assess the survival and predictors of mortality among adult patients starting highly active antiretroviral therapy at Debre Berhan Referral Hospital, North Showa, Amhara, Ethiopia. PATIENTS AND METHODS: An institution-based retrospective study was conducted among the medical records of 447 study subjects' selected using simple random sampling from January 1t, 2013 to December 30, 2018. The data was collected using a structured data abstraction checklist and analyzed using Kaplan-Meier statistics and Cox regression models. RESULTS: Among 447 adult patients, 54 patients (12.1%) had died, giving a crude death rate of 4.18 per 100 person years (95% CI=3.20-5.45). The overall estimated survival rate after initiation of antiretroviral therapy was 81.7% (95% CI=75.36-86.54%) at 72 months of follow-up. The independent predictors of mortality were clinical stage IV (HR=15.6, 95% CI=6.609-36.948), baseline opportunistic infections (HR=1.86, 95% CI=1.048-3.330), baseline Hgb<10 mg/dL (HR=4.655, 95% CI=2.253-9.619), baseline CD4<200 cells/µL (HR=4.71, 95% CI=2.275-9.751), the presence of comorbidity (HR=2.56 95% CI=1.391-4.740), being widowed (HR=3.475, 95% CI=1.412-8.550), and bedridden functional status (HR=3.069, 95% CI=1.111-8.480). CONCLUSION: Patients with opportunistic infections, advanced clinical stage disease, bedridden functional status, baseline Hgb<10 mg/dL, baseline CD4<200 cells/µL, and comorbidity should be given special care.

Adherence to insulin self administration and associated factors among diabetes mellitus patients at Tikur Anbessa specialized hospital.

BACKGROUND: The goals of diabetes treatment are to keep blood glucose levels as near normal as possible while avoiding complications. Despite the benefits of insulin therapy, many people with diabetes don't adhere to treatment. Some avoid insulin therapy or refuse to start it. Several studies investigating adherence to chronic disease treatment have evidenced that patients often discontinue their medications or even do not take them at all because they consider them ineffective or experience untoward side effects. To assess adherence to insulin self administration and associated factors among adult patients with diabetes mellitus at endocrinology unit of Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia. METHODS: A cross-sectional study was conducted from December to June 2015, on a total of 378 diabetic patients on insulin self administration using convenience sampling method. The data was collected using structured questionnaires after ethical approval and informed signed consent have been taken. The data entry and analysis was conducted using Epi info version 3.5.4 and SPSS version 21. RESULTS: One hundred twenty five (33.1%) of the respondents were found to be non-adherent to insulin self injection. Multivariate analysis identified who stopped taking insulin when they feel better, who have Heart disease and those not taking insulin when they were out of home for long time as independent factors for non adherence of insulin self administration. CONCLUSION: The factors associated with non adherence to insulin self administrations were; forgetting time of injection, deliberately, feeling better and feeling worse.

Trauma severities scores and their prediction of outcome among trauma patients in two hospitals of Addis Ababa, Ethiopia.

BACKGROUND: Trauma is the leading cause of morbidity and mortality all over the world. Developing countries including Ethiopia have been greatly affected with trauma. OBJECTIVE: To measure the seventies of trauma and their prediction of outcome for trauma patients. METHOD: Retrospective patient care record review was made from March to June 2010 on 328 trauma patients in emergency medical services of Tikur Anbessa and Yekatit 12 hospitals. Data were collected by trained nurses using check list. Trauma and Injury Severity Scoring (TRISS) method was used to measure trauma severities and prediction of their outcome. RESULT: Among 328 trauma patients. 72.9% were males. The traumas account for 161 (419.1%), were road traffic injury, followed by 59 (18. 0%) strike by blunt object. With regarding to pattern of injury: from 298 (90.9%) blunt trauma; 141 (12.9%) were head injury, followed by 138 (42.1%) pelvic injury while from 30 (9.1%) penetrating trauma: 11 (3.4%) were pelvic injury, followed by 6 (1.8%) head injury. The median of TRISS measure was 0.97 with the range of 0.014 to 0.99. Sixty (18.3%) of them died during treatment. For the outcome scoring the area under the curve at Receiver Optimization Curve (ROC) analysis was 0.97 for TRISS (P < 0.0001). The W-statistic was -4 at Z-score -3.81 while M-statistics was 0.893. CONCLUSION: The finding reveals high trauma mortality than predicted in severely injured patient. The major itrauma outcome of this study is worse than the norm in developed countries. Therefore, establishing a database to quantify severe trauma and predict its outcome for standard severe injury care seems important.

Adherence to antiretroviral therapy and its associated factors among people living with HIV/AIDS in Addis Ababa, Ethiopia.

BACKGROUND: HIV/AIDS became a chronic illness since the introduction of Anti-Retroviral-Therapy which needs ongoing assessment for adherence to prevent treatment failure. OBJECTIVE: The objective of this study was to assess antiretroviral therapy adherence and its associated factors. METHODS: A cross-sectional quantitative study was conducted on 420 People Living With HIV/AIDS (PLWHA) who were attending Anti-Retroviral-Therapy clinic at Tikur Anbessa, Zewditu and St Paul's Hospitals from March to April 2009. Systematic random sampling technique was used to select the participants from their document. Then Data were collected, checked, categorized, coded and analyzed using SPSS 15.0 statistical package. RESULT: From the total 420 respondents, 244 (58.1%) were women. Among the respondents, 308 (73.3%) had adhered to Anti-Retroviral-Therapy (ART). Respondents who had good relationship with health care provider had 3.15 times more likely to adhere to ART compared to those who had poor relationship. Those who stated stigma and discrimination as a major problem were 81% less likely to adhere to ART compared to those who stated stigma and discrimination not to be a problem at all. CONCLUSION: The findings of the study indicate that ART adherence rate to be low. The study also showed that Stigma and discrimination, and poor relationship with health care provider to be associated with low adherence. Based on the finding, keep away from stigmatization and discrimination, and enhancing good relationship need to be given attention for improving ART adherence.