ABSTRACT
OBJECTIVE: To know the cost generated by nosocomial infections, to establish the proportion of the total hospital budget used in extra-days of stay, drugs, laboratory and others items used for the treatment. METHODS: We studied 131 nosocomial infections in 82 patients attended in hospital's departments from June to August 1995. We evaluated days of stay, type of infection, episodes per patient, drugs, laboratory, and others items used in the treatment of nosocomial infections. We took percentage of cost of every point and the mean of the total cost generated by year cause nosocomial infections and a cost per infection in every department. RESULTS: The total overtime of stay was 970 days, mean per infection was 7.4. Totals days of antimicrobials was 974, mean was 11.9 days per infection. The hospital processed 410 laboratory studies, 191 cabinet studies. The total cost generated by overtime stay was $3,415,860.00, and considering also drugs, laboratory and cabinet studies $3,516,421.00. CONCLUSIONS: The cost of the nosocomial infections depends on the overtime stay, drugs, laboratory and cabinet studies needed for their treatment. Neonatology generated presented more than one infection generating higher cost. Total cost in 3 months was $3'516,421.00, nosocomial infections would take $14'065,684.00 in a year, involving 12.1% of the hospital total budget. Preventive measures must be taken trying to diminish these costs.
Subject(s)
Cross Infection/economics , Adolescent , Anti-Infective Agents/economics , Anti-Infective Agents/therapeutic use , Child , Child, Preschool , Cross Infection/diagnosis , Cross Infection/drug therapy , Cross Infection/epidemiology , Female , Hospital Costs/statistics & numerical data , Humans , Incidence , Infant , Infant, Newborn , Length of Stay/economics , Length of Stay/statistics & numerical data , Male , Mexico/epidemiologyABSTRACT
BACKGROUND: The aim of this study was to identify risk factors associated to mortality in newborn stage III necrotizing enterocolitis (NEC III). SETTING: Neonatal Intensive Care Unit (NICU) at the Hospital de Pediatría CMN Siglo XXI IMSS; Mexico City. METHODS: Twenty one clinical records were analyzed. A case-control study was realized from patients admitted in the NICU from January to November 1997. RESULTS: Two cases were excluded. The 19 that remained had 52% mortality. They were ten cases and nine controls. They were no significant differences between both groups in gestational age, birth weight, breast or formula feeding, neither X-rays nor whíte blood cells and platelet counts showed differences, except in band-count increase. Anterior abdominal wall celullitis and gut perforation, both had significative differences (p = 0.01); also shock and acute renal failure had an odds ratio of 11.2 and 72, respectively. CONCLUSIONS: The NEC mortality in this study is similar to previous communications; nevertheless, the gestational age of these patients is greater than the literature reports. The most significant risk factors found in this paper in relationship to mortality were shock and acute renal failure; both had a high odds ratio.
Subject(s)
Enterocolitis, Necrotizing/mortality , Acute Kidney Injury/etiology , Case-Control Studies , Enterocolitis, Necrotizing/complications , Enterocolitis, Necrotizing/pathology , Humans , Infant, Newborn , Risk FactorsABSTRACT
OBJECTIVE: To determine serum levels of lipid, cholesterol, triglycerides and lipoproteins in newborns and their mothers and to know the association between them. MATERIAL AND METHODS: Blood samples were taken from 200 newborns and from their mothers, and analyzed for lipid, cholesterol, triglyceride and lipoprotein content in an autoanalyzer. Data were analyzed with the Epi Info 6 program. Central tendency measurements, variance analysis and Pearson correlation coefficient were obtained. RESULTS: Average lipid levels in newborn blood samples was 625.2 +/- 130, 158.8 +/- 44 mg/dl of cholesterol, 136.9 +/- 97 mg/dl of triglycerides, 70.5 +/- 23.9 mg/dl LDL, 52.7 +/- 14 mg/dl HDL and 26.5 +/- 15.5 mg/dl VLDL. CONCLUSIONS: Newborn cholesterol levels were similar to values reported by Alpers and higher than levels published by the American Committee of Pediatric Biochemistry in USA. An association between levels in mothers and their children was found.
