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1.
J Adolesc ; 96(5): 925-939, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38477391

ABSTRACT

INTRODUCTION: While the study of conspiracy theory beliefs is a relatively new research area, there has been a rise in academic interest in recent years. The literature provides evidence of relationships between conspiracy theory beliefs and a range of factors, but the vast majority of studies are limited to adult samples, and it is unclear how such beliefs present in adolescence. METHODS: The systematic review was conducted according to the PRISMA-S format. Relevant databases were searched up to February 23, 2023, for quantitative studies related to adolescent conspiracy theory beliefs. RESULTS: The six included articles show that conspiracy theory beliefs are present from the start of adolescence, and stable from age 14 upwards, with correlations reported for mistrust and paranoid thinking. Negative relationships were reported for cognitive factors such as ontological confusion, cognitive ability, and actively open-minded thinking. Health-related beliefs correlated with adverse childhood experiences, peer problems, conduct, and sociodemographic factors. Right-wing authoritarianism and anxiety positively correlated with intergroup conspiracy theory beliefs. CONCLUSION: While some factors from adult studies are replicated in the review, there are differences between age groups. The age at which conspiracy theory beliefs begin to form indicate developmental aspects of adolescence, and possibly childhood, that require further examination. Cognitive factors show promise for interventions and should be explored further. However, the lack of studies using adolescent populations is an issue that must be resolved for a greater understanding of conspiracy theory beliefs and a move toward effective interventions.


Subject(s)
Adolescent Behavior , Humans , Adolescent , Adolescent Behavior/psychology , Trust/psychology
2.
J Exp Psychol Learn Mem Cogn ; 49(11): 1699-1714, 2023 Nov.
Article in English | MEDLINE | ID: mdl-37470985

ABSTRACT

While visual working memory has a short lifetime, residual representations can persist and disrupt currently maintained information. This phenomenon is known as proactive interference (PI), and the present study investigated whether the representations underpinning item-specific PI lose details over time. This would be expected if the memories underlying PI are susceptible to temporal processes such as decay, which is strongly disputed. In four experiments, a modified version of the recent probes task was used, requiring participants to determine whether a probe matched one of two recently presented targets. The probe sometimes matched an untested target from a previous trial, or varied in its resemblance to it, and the amount of time separating trials varied. Results revealed that PI was specific and highly disruptive at very short intervals, but its effect diminished over time. At longer intervals, a milder form of PI was present and produced by probes that were only similar to a recently encountered target. In summary, residual visual representations may remain accurate for a few seconds after encoding, before losing precise details and continuing to endure in an inexact state. (PsycInfo Database Record (c) 2023 APA, all rights reserved).


Subject(s)
Memory, Short-Term , Humans , Reaction Time , Time Factors
3.
Arch Phys Med Rehabil ; 104(9): 1447-1455, 2023 09.
Article in English | MEDLINE | ID: mdl-36935032

ABSTRACT

OBJECTIVE: To investigate the feasibility, discriminative and convergent validity, and inter-rater reliability of a lower limb tactile function and 2 body awareness assessments in children with upper motor neuron (UMN) lesions. DESIGN: Cross-sectional psychometric study. SETTING: Pediatric rehabilitation center. PARTICIPANTS: Forty individuals with UMN lesions (mean age 11.7 years, SD 3.4 years; 27 girls) and 40 neurotypically developing children of the same age participated (N=80). INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: We assessed the tactile threshold (TT) with monofilaments and body awareness with tactile localization tasks (TLTs) for structural (TLTaction) and spatial (TLTperception) body representation at the foot sole. We compared the test outcomes between children with UMN lesions and neurotypically developing children with the Wilcoxon signed-rank test. Furthermore, we quantified the relations between the 3 tests with Spearman correlations (rs) and the interrater reliability with quadratic weighted kappa (κQW). RESULTS: About 80% of the children with UMN lesions perceived the tests easy to perform. The children with UMN lesions had significantly reduced somatosensory function compared with the neurotypically developing children. For the more affected leg, we found good relations between the TT and the TLTaction (rs=0.71; P<.001) and between the 2 TLTs (rs=0.66; P<.001), and a fair relation between the TT and the TLTperception (rs=0.31; P=.06). The inter-rater reliability analyses for the sum scores showed almost perfect agreement for the TT (κQW more affected leg 0.86; less affected leg 0.81), substantial agreement for TLTaction (κQW more affected leg 0.76; less affected leg 0.63), and almost perfect agreement for TLTperception (κQW more affected leg 0.88; less affected leg 0.74). CONCLUSION: The 3 tests are feasible to assess lower limb somatosensory function in children with UMN lesions. Discriminative and convergent validity and reliability of the 3 tests were confirmed. Further studies should investigate responsiveness and association with motor function of these outcome measures.


Subject(s)
Lower Extremity , Motor Neurons , Female , Humans , Child , Cross-Sectional Studies , Reproducibility of Results , Feasibility Studies , Upper Extremity
4.
Disabil Rehabil ; 45(16): 2620-2629, 2023 08.
Article in English | MEDLINE | ID: mdl-35906774

ABSTRACT

PURPOSE: Somatosensory function of the lower limbs is rarely assessed in children with upper motor neuron lesions despite its potential relevance for motor function. We explored consensus regarding somatosensory categories (exteroception, proprioception, interoception, and body awareness), modalities, and outcome measures relevant to lower limb motor function. METHODS: Fifteen international experts with experience of somatosensory function assessment participated in this Delphi study. Surveys of four rounds, conducted online, included questions on the relevance of somatosensory categories and modalities for motor function and on the use of potential outcome measures in clinical practice. RESULTS: The experts reached consensus on the relevance of six modalities of the categories exteroception, proprioception, and body awareness. Based on their feedback, we formulated three core criteria for somatosensory outcome measures, namely suitability for clinical practice, child-friendliness, and relevance for motor function. None of the nine available outcome measures fulfilled each criterion. The experts also highlighted the importance of using and interpreting the tests in relation to the child's activity and participation. CONCLUSION: There was expert consensus on three categories and six modalities of somatosensory function relevant for lower limb motor function. However, existing outcome measures will need to be adapted for use in paediatric clinical practice. IMPLICATION FOR REHABILITATIONConsensus was established for the categories and modalities of somatosensory function relevant for lower limb motor function of children with UMN lesion.Outcome measures should cover tactile function, joint movement and joint position and dynamic position sense, and spatial and structural body representation.None of the nine existing outcome measures fulfilled the core criteria: feasibility for clinical practice, child-friendliness, and relevance to motor function.


Subject(s)
Stroke , Humans , Child , Delphi Technique , Outcome Assessment, Health Care , Lower Extremity , Motor Neurons , Upper Extremity
5.
Front Psychol ; 13: 896866, 2022.
Article in English | MEDLINE | ID: mdl-35664155

ABSTRACT

The current contents of visual working memory can be disrupted by previously formed memories. This phenomenon is known as proactive interference, and it can be used to index the availability of old memories. However, there is uncertainty about the robustness and lifetime of proactive interference, which raises important questions about the role of temporal factors in forgetting. The present study assessed different factors that were expected to influence the persistence of proactive interference over an inter-trial interval in the visual recent probes task. In three experiments, participants encoded arrays of targets and then determined whether a single probe matched one of those targets. On some trials, the probe matched an item from the previous trial (a "recent negative"), whereas on other trials the probe matched a more distant item (a "non-recent negative"). Prior studies have found that recent negative probes can increase errors and slow response times in comparison to non-recent negative probes, and this offered a behavioral measure of proactive interference. In Experiment 1, factors of array size (the number of targets to be encoded) and inter-trial interval (300 ms vs. 8 s) were manipulated in the recent probes task. There was a reduction in proactive interference when a longer delay separated trials on one measure, but only when participants encoded two targets. When working memory capacity was strained by increasing the array size to four targets, proactive interference became stronger after the long delay. In Experiment 2, the inter-trial interval length was again manipulated, along with stimulus novelty (the number of stimuli used in the experiment). Proactive interference was modestly stronger when a smaller number of stimuli were used throughout the experiment, but proactive interference was minimally affected by the inter-trial interval. These findings are problematic for temporal models of forgetting, but Experiment 3 showed that proactive interference also resisted disruption produced by a secondary task presented within the inter-trial interval. Proactive interference was constantly present and generally resilient to the different manipulations. The combined data suggest a relatively durable, passive representation that can disrupt current working memory under a variety of different circumstances.

6.
Memory ; 30(5): 591-609, 2022 05.
Article in English | MEDLINE | ID: mdl-35139751

ABSTRACT

Proactive interference - the disruptive effect of old memories on new learning - is a long-established forgetting mechanism, yet there are doubts about its impact on visual working memory and uncertainty about the kinds of information that cause proactive interference. The present study aimed to assess these issues in three experiments using a modified recent probes task. Participants encoded four target images on each trial and determined whether a probe matched one of those targets. In Experiment 1, probes matching targets from trial N-1 or N-3 damaged responding in relation to a novel probe. Proactive interference was also produced by probes differing in state to a previously experienced target. This was further assessed in Experiments 2 and 3. Here, probes differing in colour to a previous target, or matching the general target category only, produced little proactive interference. Conversely, probes directly matching a prior target, or differing in state information, hindered task performance. This study found robust proactive interference in visual working memory that could endure over multiple trials, but it was also produced by stimuli closely resembling an old target. This challenges the notion that proactive interference is produced by an exact representation of a previously encoded image.


Subject(s)
Memory, Short-Term , Proactive Inhibition , Humans , Task Performance and Analysis , Time Factors
7.
Dev Neurorehabil ; 25(5): 314-327, 2022 Jul.
Article in English | MEDLINE | ID: mdl-34872425

ABSTRACT

PURPOSE: A systematic review of the psychometric properties and feasibility of outcome measures assessing lower limb somatosensory function and body awareness in children with upper motor neuron lesion. METHODS: We followed the COnsensus-based Standards for the selection of health Measurement INstruments guidelines. Two raters independently judged the quality and risk of bias of each study. Data synthesis was performed, and aspects of feasibility were extracted. RESULTS: Twelve studies investigated eleven somatosensory function measures quantifying four modalities and eight body awareness measures quantifying two modalities. The best evidence synthesis was very low to low for somatosensory function modalities and low for body awareness modalities. Few feasibility aspects were reported (e.g., the percentage or minimum age of participants able to perform the tests). CONCLUSION: Current evidence on the psychometric characteristics of somatosensory function and body awareness outcome measures are relatively sparse. Further research on psychometric properties and practical application is needed.


Subject(s)
Lower Extremity/physiopathology , Motor Neurons/pathology , Psychometrics , Upper Extremity/innervation , Child , Feasibility Studies , Humans , Outcome Assessment, Health Care , Reproducibility of Results
8.
Int J Sports Physiol Perform ; 17(1): 37-43, 2022 01 01.
Article in English | MEDLINE | ID: mdl-34404025

ABSTRACT

PURPOSE: The purpose of this study was to assess neuromuscular performance capabilities over an in-season mesocycle in early-career professional soccer players and examine the relationship with training workload. METHODS: Neuromuscular performance capabilities (isometric knee extensor: peak force, rate of force development, and peak twitch force) of 12 professional soccer players were assessed weekly over a 6-week period. Training and match workload were also recorded over the same period for each player (high-intensity running distance). Changes in neuromuscular performance and workload variables were analyzed. RESULTS: There was evidence of fluctuations in neuromuscular performance capability over the mesocycle that reached statistical (P < .05) and practical (13.3% [peak-to-peak]) significance alongside interweek heterogeneity in training and match workload (∼17.5% [coefficient of variation], P < .05). Congruence among fluctuating patterns of intramesocycle training load and concomitant neuromuscular performance responses was noted over time for acute training load and acute:chronic workload ratio with peak force and rate of force development. CONCLUSION: Neuromuscular performance capabilities fluctuate over an in-season mesocycle and are influenced by high-intensity running workload, emphasizing the need for acute monitoring in elite soccer players.


Subject(s)
Athletic Performance , Running , Soccer , Humans , Seasons , Workload
9.
Mult Scler ; 27(11): 1657-1678, 2021 10.
Article in English | MEDLINE | ID: mdl-33876986

ABSTRACT

BACKGROUND: Fatigue is a common, debilitating symptom of multiple sclerosis (MS) without a current standardised treatment. OBJECTIVE: The aim of this systematic review with network meta-analyses was to estimate the relative effectiveness of both fatigue-targeted and non-targeted exercise, behavioural and combined (behavioural and exercise) interventions. METHODS: Nine electronic databases up to August 2018 were searched, and 113 trials (n = 6909) were included: 34 were fatigue-targeted and 79 non-fatigue-targeted trials. Intervention characteristics were extracted using the Template for Intervention Description and Replication guidelines. Certainty of evidence was assessed using GRADE. RESULTS: Pairwise meta-analyses showed that exercise interventions demonstrated moderate to large effects across subtypes regardless of treatment target, with the largest effect for balance exercise (SMD = 0.84). Cognitive behavioural therapies (CBTs) showed moderate to large effects (SMD = 0.60), with fatigue-targeted treatments showing larger effects than those targeting distress. Network meta-analysis showed that balance exercise performed significantly better compared to other exercise and behavioural intervention subtypes, except CBT. CBT was estimated to be superior to energy conservation and other behavioural interventions. Combined exercise also had a moderate to large effect. CONCLUSION: Treatment recommendations for balance and combined exercise are tentative as the certainty of the evidence was moderate. The certainty of the evidence for CBT was high.


Subject(s)
Multiple Sclerosis , Exercise , Exercise Therapy , Fatigue/etiology , Fatigue/therapy , Humans , Multiple Sclerosis/complications , Multiple Sclerosis/therapy , Network Meta-Analysis
10.
Behav Res Ther ; 137: 103464, 2021 02.
Article in English | MEDLINE | ID: mdl-31780252

ABSTRACT

Fatigue is a common and highly debilitating symptom of multiple sclerosis (MS). This meta-analytic systematic review with detailed narrative synthesis examined randomised-controlled (RCTs) and controlled trials of behavioural and exercise interventions targeting fatigue in adults with MS to assess which treatments offer the most promise in reducing fatigue severity/impact. Medline, EMBASE and PsycInfo electronic databases, amongst others, were searched through to August 2018. Thirty-four trials (12 exercise, 16 behavioural and 6 combined; n = 2,434 participants) met inclusion criteria. Data from 31 studies (n = 1,991 participants) contributed to the meta-analysis. Risk of bias (using the Cochrane tool) and study quality (GRADE) were assessed. The pooled (SMD) end-of-treatment effects on self-reported fatigue were: exercise interventions (n = 13) -.84 (95% CI -1.20 to -.47); behavioural interventions (n = 16) -.37 (95% CI -.53 to -.22); combined interventions (n = 5) -.16 (95% CI: -.36 to .04). Heterogeneity was high overall. Study quality was very low for exercise interventions and moderate for behavioural and combined interventions. Considering health care professional time, subgroup results suggest web-based cognitive behavioural therapy for fatigue, balance and/or multicomponent exercise interventions may be the cost-efficient therapies. These need testing in large RCTs with long-term follow-up to help define an implementable fatigue management pathway in MS.


Subject(s)
Cognitive Behavioral Therapy , Multiple Sclerosis , Adult , Exercise , Exercise Therapy , Fatigue/therapy , Humans , Multiple Sclerosis/complications , Multiple Sclerosis/therapy
11.
Sci Rep ; 10(1): 8302, 2020 05 19.
Article in English | MEDLINE | ID: mdl-32427935

ABSTRACT

Intradialytic exercise (ID) programs are effective and safe for hemodialysis (HD) patients to avoid functional deterioration. However, exercise is not routinely undertaken in most HD units, and we do not know if home-based (HB) programs are as effective as ID programs. The purpose of this study was to compare the effects of 16 weeks of ID exercise versus a HB exercise program for HD patients. A total of 46 patients were randomly assigned to the ID group (n = 24) or HB group (n = 22). They completed a 16-week combined exercise program 3 times/week. We measured physical activity level, physical functioning, depression level, and health-related quality of life at baseline and after 16 weeks. A significant time effect was found in both groups for the physical activity level (p = 0.012). There was also a significant group-time interaction effect for the one-leg standing test (OLST) (p = 0.049) and a significant time effect for the Short Physical Performance Battery (p = 0.013), timed up-and-go test (p = 0.005), sit-to-stand-10 (p = 0.027), right and left hand handgrip (p = 0.044, p < 0.001), one-heel left leg raise (p = 0.019), and 6-minute walking (p = 0.006), depression (p = 0.017). HRQoL remained unchanged. There was no difference between the two interventions on the tested outcomes (besides OLST). Both interventions were associated with positive changes of the physical activity levels and physical function.


Subject(s)
Exercise Therapy/methods , Exercise/physiology , Quality of Life/psychology , Renal Dialysis/methods , Renal Insufficiency, Chronic/therapy , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Pilot Projects , Renal Insufficiency, Chronic/psychology , Renal Insufficiency, Chronic/rehabilitation , Treatment Adherence and Compliance , Treatment Outcome
12.
Mem Cognit ; 48(2): 212-225, 2020 02.
Article in English | MEDLINE | ID: mdl-31873852

ABSTRACT

Despite attempts at active maintenance in the focus of attention, the fragile nature of the visual nonverbal memory trace may be revealed when the retention interval between target memoranda and probed recall on a trial is extended. In contrast, a passively maintained or unattended visual memory trace may be revealed as persisting proactive interference extending across quite extended intervals between trials in a recent probes task. The present study, comprising five experiments, used this task to explore the persistence of such a passive visual memory trace over time. Participants viewed some target visual items (for example, abstract colored patterns) followed by a variable retention interval and a probe item. The task was to report whether the probe matched one of the targets or not. A decaying active memory trace was indicated by poorer performance as the memory retention interval was extended on a trial. However, when the probe was a member of the target set from the preceding trial, task performance was poorer than a comparison novel probe, demonstrating proactive interference. Manipulations of the intertrial interval revealed that the temporal persistence of the passive memory trace of an old target was impressive, and proactive interference was largely resilient to a simple 'cued forgetting' manipulation. These data support the proposed two-process memory conception (active-passive memory) contrasting fragile active memory traces decaying over a few seconds with robust passive traces extending to tens of seconds.


Subject(s)
Attention/physiology , Recognition, Psychology/physiology , Retention, Psychology/physiology , Visual Perception/physiology , Adolescent , Adult , Female , Humans , Male , Time Factors , Young Adult
13.
Q J Exp Psychol (Hove) ; 72(6): 1561-1577, 2019 Jun.
Article in English | MEDLINE | ID: mdl-30142989

ABSTRACT

Memories-especially those containing fine details-are usually lost over time, but this study assessed whether detailed visual memories can survive a 1-week delay if retrieval practice is provided. In three experiments, participants viewed 300 objects and then completed recognition tests assessing memory for precise object exemplars and their state. The recognition tests occurred immediately after encoding and 1 week later, and required participants to distinguish between a previously seen target object and an incorrect foil. While there was forgetting when participants were tested on different sets of stimuli across the delay, retrieval practice led to an advantage in recognition performance. This effect was not simply due to mere exposure, as retrieval practice boosted recognition beyond a restudy condition, which had a second encoding opportunity but no retrieval practice. Yet more detailed analyses revealed that the effect of retrieval practice was highly dependent upon the type of information being tested (exemplar or state) and the specific foil that was presented. In addition, state information was harder to retain over the delay than exemplar information, suggesting that memory for different properties is forgotten at different rates.


Subject(s)
Memory, Long-Term/physiology , Mental Recall/physiology , Recognition, Psychology/physiology , Visual Perception/physiology , Adult , Humans , Time Factors , Young Adult
14.
PLoS One ; 13(10): e0203367, 2018.
Article in English | MEDLINE | ID: mdl-30312325

ABSTRACT

OBJECTIVE: Fatigue is prominent across many long term physical health conditions. This scoping review aimed to map the fatigue intervention literature, to ascertain if certain interventions may be effective across conditions, and if novel interventions tested in specific long term conditions may be promising for other conditions. METHODS: Scoping review methodological frameworks were used. Electronic bibliographic databases were searched (inception to November 2016) for systematic reviews of fatigue interventions in long term conditions. Inclusion criteria were: long term physical health condition; review focus on fatigue management; objective and systematic review process; primary review outcome is fatigue. Articles focussing on surgical interventions or treatments thought to trigger fatigue were excluded. A narrative synthesis was performed. RESULTS: Of 115 full texts screened, 52 reviews were included. Interventions were categorised as pharmacological and non-pharmacological (exercise, psychological/behavioural and complementary medicine). Pharmacological interventions did not consistently demonstrate benefit, except for anti-TNFs and methylphenidate which may be effective at reducing fatigue. Non-pharmacological interventions such as graded exercise and fatigue-specific psychological interventions may be effective, but heterogeneous intervention components limit conclusions. 'Complementary medicine' interventions (e.g. Chinese herbal medicines) showed promise, but the possibility of publication bias must be considered. CONCLUSIONS: Further research is necessary to inform clinical practice. The reported effectiveness of some interventions across inflammatory health conditions, such as anti-TNFs, aerobic exercise, and psychologically based approaches such as CBT, highlights a potential transdiagnostic avenue for fatigue management. More novel strategies that may be worth exploring include expressive writing and mindfulness, although the mechanisms for these in relation to fatigue are unclear. More work is needed to identify transdiagnostic mechanisms of fatigue and to design interventions based on these.


Subject(s)
Cognitive Behavioral Therapy , Depression/therapy , Exercise/physiology , Fatigue/therapy , Depression/epidemiology , Depression/physiopathology , Drugs, Chinese Herbal/therapeutic use , Fatigue/epidemiology , Fatigue/physiopathology , Health Status , Humans , Quality of Life
15.
PLoS One ; 13(8): e0201035, 2018.
Article in English | MEDLINE | ID: mdl-30133445

ABSTRACT

Functional tests are commonly used for chronic kidney disease (CKD) patients undergoing hemodialysis (HD). However, the relative and absolute reliability of such physical performance-outcome assessments must first be determined in specific patient cohorts. The aims of this study were to assess the relative and the absolute reliability of the Short Physical Performance Battery (SPPB), One-Legged Stance Test (OLST), and Timed Up and Go (TUG) test, as well as the minimal detectable change (MDC) scores for these tests in CKD patients receiving HD. Seventy-one end-stage CKD patients receiving HD therapy, aged between 21 and 90 years, participated in the study. The patients completed two testing sessions one to two weeks apart and performed by the same examiner, comprising the following tests: the SPPB (n = 65), OLST (n = 62), and TUG test (n = 66). High intraclass correlation coefficients (≥0.90) were found for all the tests, suggesting that their relative reliability is excellent. The MDC scores for the 90% confidence intervals were as follows: 1.7 points for the SPPB, 11.3 seconds for the OLST, and 2.9 seconds for the TUG test. The reliability of the SPPB, OLST, and TUG test for this sample were all considered to be acceptable. The MDC data generated by these tests can be used to monitor meaningful changes in the functional capacity of the daily living-related activity of CKD patients on HD.


Subject(s)
Exercise Therapy/methods , Kidney Failure, Chronic/physiopathology , Kidney Function Tests/methods , Adult , Aged , Aged, 80 and over , Disability Evaluation , Exercise , Female , Gait/physiology , Humans , Kidney Failure, Chronic/classification , Kidney Failure, Chronic/therapy , Kidney Function Tests/statistics & numerical data , Male , Mass Screening/methods , Middle Aged , Physical Functional Performance , Postural Balance/physiology , Renal Dialysis/methods , Reproducibility of Results , Time and Motion Studies
16.
Exp Psychol ; 65(3): 139-148, 2018 May.
Article in English | MEDLINE | ID: mdl-29905112

ABSTRACT

Retroactive interference occurs when new information disrupts the retention of an existing representation, but its effects on visual short-term memory remain poorly understood. The present study examined three factors predicted to influence domain-specific retroactive interference, including the type of distractor, its temporal position, and the length of the retention interval. Participants compared target and test objects over a brief interval that either was unfilled or contained a similar or dissimilar distractor occurring 200 ms or 1.5 s after the target offset. Retention was influenced by the temporal position of the distractor and its relationship with the to-be-remembered target. Specifically, retroactive interference was only observed following the presentation of a dissimilar distractor that occurred 1.5 s after the target. These results suggest that novel distractors may be particularly interfering.


Subject(s)
Audiovisual Aids/trends , Memory, Short-Term/physiology , Adult , Attention , Female , Humans , Learning , Male , Time Factors , Young Adult
17.
Neurodegener Dis Manag ; 7(3): 219-230, 2017 Jun.
Article in English | MEDLINE | ID: mdl-28631984

ABSTRACT

Although exercise training has been advocated as a nonpharmacological treatment for multiple sclerosis (MS) related fatigue, no consensus exists regarding its effectiveness. To address this, we collated meta-analytic reviews that explored the effectiveness of exercise training for the treatment of MS-related fatigue. We searched five online databases for relevant reviews, published since 2005, and identified 172 records. Five reviews were retained for systematic extraction of information and evidence quality analysis. Although our review synthesis indicated that exercise training interventions have a moderate effect on fatigue reduction in people with MS, no clear insight was obtained regarding the relative effectiveness of specific types or modes of exercise intervention. Moreover, Grading of Recommendation Assessment, Development and Evaluation revealed that the overall quality of evidence emanating from these five reviews was 'very low'.


Subject(s)
Exercise Therapy , Fatigue/rehabilitation , Meta-Analysis as Topic , Multiple Sclerosis/complications , Fatigue/etiology , Humans , Treatment Outcome
18.
Adv Cogn Psychol ; 13(4): 314-322, 2017.
Article in English | MEDLINE | ID: mdl-29362647

ABSTRACT

Retroactive interference (RI) is a primary source of forgetting and occurs when new information disrupts or damages an existing memory. Prior research has shown that children are susceptible to RI when the to-be-remembered and interfering information are similar, but it is unclear whether they are also vulnerable to nonspecific RI . This form of interference occurs when a memory is disrupted by an unrelated and dissimilar distractor task, and the present study explored six- and seven-year-olds susceptibility to such nonspecific RI. In two experiments, participants learnt a list of words and completed a free recall test 5 min later. During the interval, participants either remained quiet (the control condition) or completed spot-the-difference puzzles (the interference condition). In Experiment 1, the children were highly susceptible to nonspecific interference, whereas a sample of adults were not affected by the interfering task. However, when a new sample of children were given more time to encode and retrieve the words in Experiment 2, they were able to resist interference. Nonspecific RI can damage children's memory, but they do have the ability to prevent this form of interference in certain circumstances.

19.
J Cardiovasc Nurs ; 31(4): 323-30, 2016.
Article in English | MEDLINE | ID: mdl-27299758

ABSTRACT

The purpose of this study was to investigate the effects of 2 types of transcutaneous electrical nerve stimulation (TENS) on walking distance and measures of pain in patients with peripheral arterial disease (PAD) and intermittent claudication (IC). In a phase 2a study, 40 participants with PAD and IC completed a graded treadmill test on 2 separate testing occasions. Active TENS was applied to the lower limb on the first occasion; and placebo TENS, on the second. The participants were divided into 2 experimental groups. One group received high-frequency TENS; and the other, low-frequency TENS. Measures taken were initial claudication distance, functional claudication distance, and absolute claudication distance. The McGill Pain Questionnaire (MPQ) vocabulary was completed at the end of the intervention, and the MPQ-Pain Rating Index score was calculated. Four participants were excluded from the final analysis because of noncompletion of the experimental procedure. Median walking distance increased with high-frequency TENS for all measures (P < .05, Wilcoxon signed rank test, all measures). Only absolute claudication distance increased significantly with low-frequency TENS compared with placebo (median, 179-228; Ws = 39; z = 2.025; P = .043; r = 0.48). No difference was observed between reported median MPQ-Pain Rating Index scores: 21.5 with placebo TENS and 21.5 with active TENS (P = .41). Transcutaneous electrical nerve stimulation applied to the lower limb of the patients with PAD and IC was associated with increased walking distance on a treadmill but not with any reduction in pain. Transcutaneous electrical nerve stimulation may be a useful adjunctive intervention to help increase walking performance in patients with IC.


Subject(s)
Intermittent Claudication/therapy , Transcutaneous Electric Nerve Stimulation , Walking , Humans , Pain Measurement , Peripheral Arterial Disease
20.
Memory ; 24(6): 757-65, 2016 07.
Article in English | MEDLINE | ID: mdl-26274349

ABSTRACT

This study aimed to determine whether the recall of gestures in working memory could be enhanced by verbal or gestural strategies. We also attempted to examine whether these strategies could help resist verbal or gestural interference. Fifty-four participants were divided into three groups according to the content of the training session. This included a control group, a verbal strategy group (where gestures were associated with labels) and a gestural strategy group (where participants repeated gestures and were told to imagine reproducing the movements). During the experiment, the participants had to reproduce a series of gestures under three conditions: "no interference", gestural interference (gestural suppression) and verbal interference (articulatory suppression). The results showed that task performance was enhanced in the verbal strategy group, but there was no significant difference between the gestural strategy and control groups. Moreover, compared to the "no interference" condition, performance decreased in the presence of gestural interference, except within the verbal strategy group. Finally, verbal interference hindered performance in all groups. The discussion focuses on the use of labels to recall gestures and differentiates the induced strategies from self-initiated strategies.


Subject(s)
Gestures , Memory, Short-Term/physiology , Adolescent , Adult , Female , Humans , Male , Young Adult
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