1.
J Org Chem
; 89(7): 5126-5133, 2024 Apr 05.
Article
in English
| MEDLINE
| ID: mdl-38466932
ABSTRACT
In this study, we introduce a convenient Heck vinylation protocol that eliminates the requirement for ethylene gas as a coupling partner. In contrast to traditional methodologies, quaternary ammonium salts can serve as solid olefin precursors under ambient atmosphere conditions. The practicality of this method, distinguished by its convenience and safety in a one-pot reaction, renders it appealing for applications in research and discovery context.