ABSTRACT
Eye drops and ointments containing corticosteroids moderately influence plasma cortisol levels. Subconjunctival or retrobulbar injections of dexamethasone phosphate (4 mg/day) have a pronounced effect on endogenous cortisol synthesis. This effect, however, is reversible. If additional oral corticosteroid medication is given over a prolonged period of time the function of the adrenal glands may be seriously damaged for more than a year.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , Dexamethasone/therapeutic use , Hydrocortisone/blood , Uveitis/drug therapy , Administration, Topical , Drug Therapy, Combination , Humans , PrednisoloneABSTRACT
the plasmacortisol-levels of 27 patients suffering from glaucoma were compared with those of 156 healthy persons. There was no difference between the two groups compared. In addition, a diurnal inversion of the plasmacortisol-level in patients suffering from glaucoma as reported in the literature was not found.
