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Artif Intell Med ; 46(1): 19-36, 2009 May.
Article in English | MEDLINE | ID: mdl-18824335

ABSTRACT

OBJECTIVE: Medical critiquing systems compare clinical actions performed by a physician with a predefined set of actions. In order to provide useful feedback, an important task is to find differences between the actual actions and a set of 'ideal' actions as described by a clinical guideline. In case differences exist, the critiquing system provides insight into the extent to which they are compatible. METHODS AND MATERIAL: We propose a computational method for such critiquing, where the ideal actions are given by a formal model of a clinical guideline, and where the actual actions are derived from real world patient data. We employ model checking to investigate whether a part of the actual treatment is consistent with the guideline. RESULTS: We show how critiquing can be cast in terms of temporal logic, and what can be achieved by using model checking. Furthermore, a method is introduced for off-line computing relevant information which can be exploited during critiquing. The method has been applied to a clinical guideline of breast cancer in conjunction with breast cancer patient data.


Subject(s)
Artificial Intelligence , Breast Neoplasms/therapy , Carcinoma, Ductal, Breast/therapy , Computer Simulation , Decision Support Systems, Clinical , Models, Theoretical , Breast Neoplasms/diagnosis , Carcinoma, Ductal, Breast/diagnosis , Female , Guideline Adherence , Humans , Logic , Medical Records Systems, Computerized , Patient Selection , Practice Guidelines as Topic , Systems Integration , Time Factors
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