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J Am Acad Dermatol ; 52(2 Suppl 1): 45-7, 2005 Feb.
Article in English | MEDLINE | ID: mdl-15692513

ABSTRACT

Specific skin lesions are rare in Waldenstrom's macroglobulinemia (WM). We report a case of a 58-year-old man who presented macules, papules, and an erythema of the trunk with the "deck-chair" sign revealing the relapse of WM. Histologic and immunohistochemical examinations confirmed that cutaneous lesions were related to specific infiltration with neoplastic cells. Remission of both skin lesions and immunological abnormalities was obtained with oral cyclophosphamide.


Subject(s)
Antineoplastic Agents, Alkylating/therapeutic use , Cyclophosphamide/therapeutic use , Skin Diseases/drug therapy , Skin Diseases/pathology , Waldenstrom Macroglobulinemia/drug therapy , Waldenstrom Macroglobulinemia/pathology , Humans , Male , Middle Aged , Skin Diseases/immunology , Waldenstrom Macroglobulinemia/immunology
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