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1.
Int J Paediatr Dent ; 15(3): 220-3, 2005 May.
Article in English | MEDLINE | ID: mdl-15854120

ABSTRACT

The present paper describes the dental presentation of a female patient with Kartagener's syndrome. There are no reports in the literature identifying dental anomalies in patients with this condition. The subject presented with the congenital absence of an upper lateral incisor, enamel hypoplasia and aberrant tooth morphology.


Subject(s)
Kartagener Syndrome/complications , Tooth Abnormalities/etiology , Adolescent , Anodontia/etiology , Dental Enamel Hypoplasia/etiology , Female , Humans
2.
Water Sci Technol ; 47(7-8): 305-10, 2003.
Article in English | MEDLINE | ID: mdl-12793694

ABSTRACT

In the UK, the recycling of sewage sludge to land is expected to double by 2006 but the security of this route is threatened by environmental concerns and health scares. Strategic investment is needed to ensure sustainable and secure sludge recycling outlets. At present, the security of this landbank for sludge recycling is determined by legislation relating to nutrient rather than potentially toxic elements (PTEs) applications to land--especially the environmental risk linked to soil phosphorus (P) saturation. We believe that not all land has an equal risk of contributing nutrients derived from applications to land to receiving waters. We are currently investigating whether it is possible to minimise nutrient loss by applying sludge to land outside Critical Source Areas (CSAs) regardless of soil P Index status. Research is underway to develop a predictive and spatially-sensitive, semi-distributed model of critical thresholds for sludge application that goes beyond traditional "end-of-pipe" or "edge-of-field" modelling, to include hydrological flow paths and delivery mechanisms to receiving waters from non-point sources at the catchment scale.


Subject(s)
Models, Theoretical , Sewage/chemistry , Waste Disposal, Fluid/methods , Water Pollution/prevention & control , Conservation of Natural Resources , Phosphorus , Risk Assessment , United Kingdom
3.
Int J Paediatr Dent ; 13(2): 127-9, 2003 Mar.
Article in English | MEDLINE | ID: mdl-12605632

ABSTRACT

This paper describes the case of a day old baby who was admitted to hospital because of the presence of a large intraoral swelling that was preventing her from breast feeding. Clinical examination showed a firm, pedunculated, lobulated nodule protruding from the mouth and attached to the maxillary alveolus to the left of the midline. The mucosa was normal in appearance. The growth was excised under local anaesthesia and showed a histological appearance consistent with a congenital epulis of the newborn. Healing was complete and no recurrence was seen at review after two weeks. Conservative treatment of congenital epulis is often sufficient but in this case, the nodule prevented feeding. Excision was incomplete but, as in other cases treated in the same way, there has been no obvious tendency to recur.


Subject(s)
Gingival Neoplasms/congenital , Granular Cell Tumor/congenital , Female , Gingival Neoplasms/surgery , Granular Cell Tumor/surgery , Humans , Infant, Newborn , Maxilla
4.
Br J Cancer ; 85(3): 422-7, 2001 Aug 03.
Article in English | MEDLINE | ID: mdl-11487275

ABSTRACT

2-18% of ductal carcinoma-No Special Type (NST) are reported to express basal cell keratin 14 and such tumours may have a different metastatic pattern and prognosis. We performed immunohistochemistry for cytokeratins 19 (luminal) and 14 (basal) on 92 ductal carcinoma-NST. Those tumours showing CK14 expression were further characterized by immunohistochemistry for myoepithelial cell phenotype and analysed by comparative genomic hybridization. The 7 cases of ductal carcinoma-NST exhibiting a basal cell phenotype were all grade III tumours and showed a molecular cytogenetic profile similar to more conventional myoepithelial cell carcinomas. Therefore it appears that grade III invasive ductal carcinomas contain a subset of tumours with specific morphological and cytogenetic characteristics, and probably prognosis for the patient.


Subject(s)
Breast Neoplasms/pathology , Carcinoma, Basal Cell/pathology , Carcinoma, Ductal, Breast/pathology , Myoepithelioma/pathology , Adult , Aged , Aged, 80 and over , Biomarkers, Tumor/metabolism , Breast Neoplasms/metabolism , Carcinoma, Basal Cell/metabolism , Carcinoma, Ductal, Breast/metabolism , Cell Differentiation , Humans , Immunoenzyme Techniques , Keratins/metabolism , Male , Middle Aged , Myoepithelioma/metabolism , Neoplasm Proteins/metabolism , Neoplasm Staging , Nucleic Acid Hybridization , Prognosis
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