[Cytologic picture of medullary carcinoma of the thyroid gland]. / K cytologickému obrazu medulárního karcinomu stítné zlázy.

The authors present cytological and clinical features of six cases of medullary carcinoma of the thyroid. They are quoting a review of the literature about the cytological picture of medullary carcinoma of the thyroid and they draw attention to the advances of immunocytology.

[Sjögren's syndrome]. / Sjögrenov syndróm.

The authors present an account on Sjögren's syndrome--clinical manifestations, diagnosis, pathogenetic aspects and treatment. The diagnosis was based on three findings: keratoconjunctivitis sicca, stomatodynia--xerostomia and other immunological, diseases. The authors used different immunological examinations, bioptic examination of the oral mucosa and parotid glands. As to gastroenterological examinations, the gastric secretion is examined according to Lambling's method, the gastroduodenum is subjected to radiographic examination, endoscopy is performed as well as a bioptic examination of the gastroduedenal mucosa.

[Antibodies against gastric parietal cells and thyroglobulin in various diseases in humans]. / Protilátky proti antigénu parietálnych buniek zalúdka a tyreoglobulínu pri rôznych ochoreniach cloveka.

The authors examined antibodies against antigen of gastric parietal cells using the method of reaction of complement-binding and the immunofluorescence test in 662 patients. Concurrently they examined in 443 patients of this group also antibodies against thyroglobulin. The group comprised 312 men and 350 women. For statistical evaluation the chi 2 test was used. Antibodies against the antigen of parietal cells were positive at the level of significance p less than 0.05 in the group with other diseases, at the level of significance of p less than 0.01 in dyspeptic syndrome, and at the level of significance p less than 0.001 in hypothyroidism and in chronic hepatopathies. The immunofluorescence test was statistically significant at the level of p less than 0.01 only in duodenal ulceration, at the level of p less than 0.001 in dyspeptic syndrome, hypothyroidism, hyperthyroidism, chronic hepatopathies, chronic pancreatitis, cholecystopathies, nephropathies and in the group of other diseases. Thyroid antibodies were positive with titres of p less than 1: 50 in 5.63, with titres of p less than 1: 5000 in 3.03%. The mentioned disease have not only pathomorphological and aetiological similarities but there is also serological overlapping.

[Significance of angiographic studies in the diagnosis of non-typical epigastric disorders]. / Význam angiografického vysetrenia v diagnostike netypických epigastrických tazkostí.

The authors analyze the possibilities and importance of angiographic examinations in the clinical differential diagnosis of patients with atypical epigastric complaints. They demonstrate that in congenital anomalies of the arteries tripus Halleri the examinations do not make it possible to assess hypoperfusion of the epigastric organs. Based on data in the literature they point out that there is often disagreement between clinical symptoms and pressure gradients of intravasally angiographically stenoses of the trunk of the coeliac vein found on operation. From hitherto assembled results it may be, however, expected that two-dimensional Doppler ultrasonic evaluation of the blood flow through the blood vessels will contribute towards the objectivization of the assessment of the blood supply of the epigastric organs. The non-invasive examination can be used also during activity of organs or after administration of drugs.

The excretion of free cortisol, cortisone, cortisol sulfate and cortisone sulfate in peripheral vascular disease, diabetes mellitus and hyperthyroidism.

In four groups of persons, 1/healthy individuals, 2/ patients with diabetes mellitus, 3/ patients with peripheral vascular disease, and 4/ patients with hyperthyroidism, the urinary excretion of free cortisol, cortisone, cortisol sulfate and cortisone sulfate was estimated. In groups 2 and 3 the excretion of all four substances was elevated. In hyperthyroidism a preponderance of free cortisone over cortisol was registered. The ratios of the followed substances suggest in patients with peripheral vascular disease a detoriation in the normal excretion of the followed corticoids, based on a preponderance of 11-OH-corticosteroids over their 11-oxo-derivatives. This observation could be implicated in the mild hyperglycemia or decreased glucose tolerance, that is often found in atherosclerotic disease.