ABSTRACT
The experimentally measured input-output characteristics of optically pumped semiconductor microcavities exhibits unexpected oscillations modifying the fundamentally linear slope in the excitation power regime below lasing. A systematic microscopic analysis reproduces these oscillations, identifying them as a genuine quantum-memory effect, i.e., a photon-density correlation accumulated during the excitation. With the use of projected quantum measurements, it is shown that the input-output oscillations can be controlled and enhanced by an order of magnitude when the quantum fluctuations of the pump are adjusted.
ABSTRACT
A minimally invasive laser-induced injury model is described to study thrombus development in mice in vivo. The protocol involves focusing the beam of an argon-ion laser through a compound microscope on the vasculature of a mouse ear that is sufficiently thin such that blood flow can be visualized by intravital microscopy. Two distinct injury models have been established. The first involves direct laser illumination with a short, high-intensity pulse. In this case, thrombus formation is inhibited by the GPIIb/IIIa antagonist, G4120. However, the anticoagulants, hirulog, PPACK, and NapC2 have minimal effect. This indicates that thrombus development induced by this model mainly involves platelet interactions. The second model involves low-intensity laser illumination of mice injected with Rose Bengal dye to induce photochemical injury in the region of laser illumination. Thrombi generated by this latter procedure have a slower development and are inhibited by both anticoagulant and anti-platelet compounds.
Subject(s)
Blood Coagulation/physiology , Blood Platelets/physiology , Blood Vessels/pathology , Disease Models, Animal , Lasers/adverse effects , Thrombosis/pathology , Amino Acid Chloromethyl Ketones/pharmacology , Animals , Antithrombins/pharmacology , Blood Coagulation/drug effects , Blood Platelets/drug effects , Blood Vessels/drug effects , Blood Vessels/ultrastructure , Fibrinolytic Agents/pharmacology , Fluorescent Dyes/pharmacology , Mice , Mice, Inbred C57BL , Microscopy, Electron , Peptides, Cyclic/pharmacology , Platelet Aggregation Inhibitors/pharmacology , Rose Bengal/pharmacology , Sulfoxides/pharmacology , Thrombosis/etiology , Thrombosis/prevention & control , Time FactorsABSTRACT
The localization of excitons on quantum-dot-like compositional fluctuations has been observed in temperature-dependent near-field magnetophotoluminescence spectra of InGaAsN. Localization is driven by the giant bowing parameter of these alloys and manifests itself by the appearance of ultranarrow lines (half-width <1 meV) at temperatures below 70 K. We show how near-field optical scanning microscopy can be used for the estimation of the size, density, and nitrogen excess of individual compositional fluctuations (clusters), thus revealing random versus phase-separation effects in the distribution of nitrogen.
ABSTRACT
An optically controlled reflection modulator has been demonstrated that consists of a combination of a GaAs-AlGaAs n-i-p-i doping structure with a multiple-quantum-well structure on top of a distributed Bragg reflector, all grown by molecular-beam epitaxy. A modulation of approximately 60% is obtained on our test structure, corresponding to a differential change of absorption coefficient in the quantum wells of approximately 7500/cm. Changes in reflectance can be observed with a control beam power as low as 1.5 microW. This device structure has the potential of being developed as an optically addressed spatial light modulator for optical information processing.
ABSTRACT
Promising approaches for achieving optically addressed spatial light modulators (O-SLMs) are investigated based on combining nipi and multiple quantum well structures. Theoretical aspects of photooptic effects achievable in such structures are treated. Test structures are grown by molecular beam epitaxy using two material systems, (In,Ga)As/GaAs and (Al,Ga)As/GaAs. Experiments show large optically controlled modulation of the absorption coefficient in the quantum well layers ( approximately 10(4) cm(-1)), a log power dependence on the control signal, millisecond and shorter time response, and generally predictable behavior. The results are encouraging for several different O-SLM device structures proposed.
ABSTRACT
The electron lithographic fabrication of high quality diffraction gratings with periods in the 0.25-microm < a(o) < 1.5-microm range is reported. The negative electron resist employed is a copolymer of glycidyl methacrylate and ethyl acrylate with a sensitivity about 15 times better than that of poly(methyl methacrylate), a positive resist. A new scan generator with linearity accurate to 1 part in 10(4) and locked onto the 60-Hz power supplies is described. Gratings with up to 3000 lines were fabricated with long range order deltaa(o)/a(o)
