ABSTRACT
A case of diffuse retroperitoneal lymphangiomatosis manifested by oedema of the left lower limb is reported. Non-invasive exploratory methods revealed a retroperitoneal pseudo-tumoral image. At laparotomy, a retro- and subperitoneal infiltration was discovered, and histology showed benign smooth muscle proliferation developed from the muscular layer of lymph vessels. There is no known successful surgical procedure for this type of lesion, and none of the treatments tested (oophorectomy or hormonal therapy) has proved to be effective.
Subject(s)
Lymphangiomyoma/pathology , Lymphoproliferative Disorders/pathology , Retroperitoneal Neoplasms/pathology , Adult , Edema/etiology , Female , Humans , Leg , Lymphangiomyoma/complications , Lymphangiomyoma/therapy , Ovariectomy , Retroperitoneal Neoplasms/complications , Retroperitoneal Neoplasms/therapySubject(s)
Anemia, Hemolytic, Autoimmune/drug therapy , Autoimmune Diseases/drug therapy , Immunosuppressive Agents/therapeutic use , Lupus Erythematosus, Systemic/drug therapy , Purpura, Thrombocytopenic/drug therapy , Azathioprine/therapeutic use , Cyclophosphamide/therapeutic use , Humans , Mercaptopurine/therapeutic use , Methotrexate/therapeutic use , Nitrogen Mustard Compounds/therapeutic use , Thioguanine/therapeutic useABSTRACT
Antiserums produced against certain isolated human myeloma IgGglobulins and absorbed in order to show only individual antigenic specificity crossreact with certain Waldenstrom IgM-globulins. Some of the common antigenic determinants revealed by these cross-reactions depend on the tertiary and quaternary structure of the IgG and IgM molecules and are independent of their K and L light-chain antigenic types.
