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Clin Exp Dermatol ; 34(6): 694-7, 2009 Aug.
Article in English | MEDLINE | ID: mdl-19323660

ABSTRACT

BACKGROUND: Androgenic alopecia is known to be androgen-dependent. Insulin is found in hair follicles and may play a role in the regulation of androgen metabolism and the hair-growth cycle. OBJECTIVES: To compare the insulin resistance between people with androgenic alopecia and a control group. METHODS: A case-control study was conducted with 97 cases in the patient and 87 in the control group. Serum fasting insulin level, fasting blood glucose, serum total cholesterol, triglyceride and high-density lipoprotein (HDL) were all measured in both groups. RESULTS: There was no difference in serum fasting insulin level, fasting blood glucose, serum total cholesterol, triglyceride, HDL and insulin resistance between the two groups (P > 0.05). CONCLUSION: Despite previous reports suggesting a link, our study found no significant relationship between insulin resistance and androgenic alopecia. Further studies are warranted.


Subject(s)
Alopecia/metabolism , Hair Follicle/metabolism , Insulin Resistance , Adult , Alopecia/blood , Blood Glucose/metabolism , Case-Control Studies , Cholesterol/blood , Fasting/blood , Humans , Insulin/blood , Male , Triglycerides/blood
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